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1254508 USP

Estriol

United States Pharmacopeia (USP) Reference Standard

Synonym: 1,3,5(10)-Estratriene-3,16α,17β-triol, 16α-Hydroxyestradiol, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene

  • CAS Number 50-27-1

  • Empirical Formula (Hill Notation) C18H24O3

  • Molecular Weight 288.38

  •  Beilstein/REAXYS Number 2508172

  •  MDL number MFCD00003691

  •  PubChem Substance ID 329749756

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards E - F More...
grade   pharmaceutical primary standard
mfr. no.   USP
mp   280-282 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
SMILES string   C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O
InChI   1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1
InChI key   PROQIPRRNZUXQM-ZXXIGWHRSA-N

Description

General description

Estriol is found to be a major estrogen in pregnant women. It originates in the placenta from the estrogen precursors, made by the fetal adrenal gland and liver. Estriol levels are directly related to the delivery of the fetus and serve as an index of the fetal well-being.

Application

Estriol may be used as a pharmaceutical primary standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

TLC Analysis of Hormones on HPTLC Silica Gel 60 RP-18 wF 254s with Concentrating Xone

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Hormones on HPTLC Silica Gel 60 RP-18 wF 254s with Concentrating Xone
Keywords: Chromatography, Thin layer chromatography

TLC Analysis of Hormones on HPTLC Silica Gel 60 RP-18 wF254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Hormones on HPTLC Silica Gel 60 RP-18 wF254s
Keywords: Thin layer chromatography

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