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1357056 USP

Leflunomide Related Compound B

United States Pharmacopeia (USP) Reference Standard

Synonym: 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards L - M More...
grade   pharmaceutical primary standard
InChI Key   UTNUDOFZCWSZMS-YFHOEESVSA-N
form   neat
Featured Industry   Pharmaceutical (small molecule)
format   neat

Description

General description

Leflunomide Related Compound B (2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide is a malononitrilamide which is a water soluble metabolite of Leflunomide. It is considered as a noncompetitive inhibitor of dihydro-orotate dehydrogensae. This metabolite has been reported to initially target activated lymphocytes.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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