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1366002 USP

Lidocaine

United States Pharmacopeia (USP) Reference Standard

Synonym: 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine

  • CAS Number 137-58-6

  • Empirical Formula (Hill Notation) C14H22N2O

  • Molecular Weight 234.34

  •  MDL number MFCD00026733

  •  PubChem Substance ID 329750054

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites,
grade   pharmaceutical primary standard
form   neat
mfr. no.   USP
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   CCN(CC)CC(=O)Nc1c(C)cccc1C
InChI   1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
InChI key   NNJVILVZKWQKPM-UHFFFAOYSA-N
Gene Information   human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

GC Analysis of Basic Drugs on Equity®-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Basic Drugs on Equity®-5
Keywords: Chromatography, Gas chromatography, Purification

GC Analysis of Basic Drugs on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents GC Analysis of Basic Drugs on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

HPLC Analysis of Anesthetics, Local on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anesthetics, Local on Ascentis® Phenyl
Keywords: Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC after Sample Prep using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC after Sample Prep using HybridSPE®-Phospholipid
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Sample preparations, Separation, Solid phase extractions, Solvents

LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC: Improvement in Analyte Response after Solid Phase Extraction (SPE) using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC: Improvement in Analyte Response after Solid Phase Extraction (SPE) using HybridSPE®-Phospholipid
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Precipitation, Sample preparations, Separation, Solid phase extractions, Solvents

LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC

From our library of Articles, Sigma-Aldrich presents LC/MS (TOF) Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Separation, Solvents

LC/MS Analysis of Anesthetics on Ascentis® Express F5

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Anesthetics on Ascentis® Express F5
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

LC/MS Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC following Sample Prep using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Antiarrhythmic Drugs and Metabolites in Plasma on Ascentis® Express HILIC following Sample Prep using HybridSPE®-Phospholipid
Keywords: Chromatography, Clinical, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Sample preparations, Solid phase extractions, Solvents

LC/MS Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Antiarrhythmic Drugs and Metabolites on Ascentis® Express HILIC
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Reversed-phase chromatography, Separation, Solid phase extractions

Peer-Reviewed Papers
15

References

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PHR1034 Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material
PHR1257 Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

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