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1370305 USP

Lorazepam

United States Pharmacopeia (USP) Reference Standard

Synonym: (±)-Lorazepam, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one

  • CAS Number 846-49-1

  • Empirical Formula (Hill Notation) C15H10Cl2N2O2

  • Molecular Weight 321.16

  •  MDL number MFCD00063406

  •  PubChem Substance ID 329750258

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards L - M More...
grade   pharmaceutical primary standard
mfr. no.   USP
drug control   USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
Featured Industry   Pharmaceutical (small molecule)
SMILES string   OC1N=C(c2ccccc2Cl)c3cc(Cl)ccc3NC1=O
InChI   1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
InChI key   DIWRORZWFLOCLC-UHFFFAOYSA-N
Gene Information   human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

Description

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Lorazepam Enantiomers on Astec® (R,R) P-CAP™

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Lorazepam Enantiomers on Astec® (R,R) P-CAP™
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Lorazepam Enantiomers on Astec® CHIROBIOTIC® T

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Lorazepam Enantiomers on Astec® CHIROBIOTIC® T
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Lorazepam Enantiomers on Astec® CHIROBIOTIC® TAG

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Lorazepam Enantiomers on Astec® CHIROBIOTIC® TAG
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

UHPLC/MS Analysis of Benzodiazepines and Glucuronide Metabolites on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Benzodiazepines and Glucuronide Metabolites on Titan™ C18
Keywords: High performance liquid chromatography, Mass spectrometry, Metabolites, Separation, Solvents

UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion

From our library of Articles, Sigma-Aldrich presents UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Sample preparations, Solid phase extractions

Peer-Reviewed Papers
15

References

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