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1387002 USP

Mepivacaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym: 1-Methyl-2′,6′-pipecoloxylidine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride

  • CAS Number 1722-62-9

  • Empirical Formula (Hill Notation) C15H22N2O · HCl

  • Molecular Weight 282.81

  •  MDL number MFCD00144738

  •  PubChem Substance ID 329750362

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards L - M More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   USP
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl
InChI   1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
InChI key   RETIMRUQNCDCQB-UHFFFAOYSA-N
Gene Information   human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Mepivacaine Enantiomers on Astec® CHIROBIOTIC® V2

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Mepivacaine Enantiomers on Astec® CHIROBIOTIC® V2
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

LC/MS Analysis of Anesthetics on Ascentis® Express F5

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Anesthetics on Ascentis® Express F5
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

Peer-Reviewed Papers
15

References

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PHR1955 Mepivacaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

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