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V900323 Sigma-Aldrich

Hydroxyurea

Vetec, reagent grade, ≥98%

Synonym: Hydroxycarbamide

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Properties

grade   reagent grade
product line   Vetec
assay   ≥98%
SMILES string   NC(=O)NO
InChI   1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChI key   VSNHCAURESNICA-UHFFFAOYSA-N
Gene Information   human ... RRM1(6240), RRM2(6241), RRM2B(50484)

Description

Packaging

100, 250 g in poly bottle

Biochem/physiol Actions

Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.

Legal Information

Vetec is a trademark of Sigma-Aldrich International GmbH

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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