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V900339 Sigma-Aldrich

Cytosine β-D-arabinofuranoside

Vetec reagent grade, 90%

Synonym: (β-D-Arabinofuranosyl)cytosine, Ara-C, Arabinocytidine, Arabinosylcytosine, Cytarabine, Cytosine arabinoside

  • CAS Number 147-94-4

  • Empirical Formula (Hill Notation) C9H13N3O5

  • Molecular Weight 243.22

  •  Beilstein/REAXYS Number 89175

  •  EC Number 205-705-9

  •  MDL number MFCD00066487

  •  PubChem Substance ID 329829757

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Properties

grade   Vetec reagent grade
assay   90%
SMILES string   NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
InChI   1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
InChI key   UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Gene Information   human ... POLA1(5422), POLA2(23649), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558)

Description

Packaging

1 g in poly bottle

Biochem/physiol Actions

Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.

Legal Information

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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