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Search Results: 176
glycine dehydrogenase (decarboxylating)
Synonyms: GCE GCSP HYGN1
Species: Human GLDC (2731), Mouse Gldc (104174), Rat Gldc (309312), Zebrafish gldc (321621), domestic cat GLDC (101100163), cow GLDC (507688), Horse GLDC (100060355), dog GLDC (481534), chicken GLDC (374222), sheep GLDC (101117476), Domestic Rabbit GLDC (100343694), domestic guinea pig Gldc (100714862), naked mole-rat Gldc (101725465)
Gene ID:
Human(2731) glycine dehydrogenase (decarboxylating)
Mouse(104174) glycine decarboxylase
Rat(309312) glycine dehydrogenase (decarboxylating)
Zebrafish(321621) glycine dehydrogenase (decarboxylating)
domestic cat(101100163) glycine dehydrogenase (decarboxylating)
cow(507688) glycine dehydrogenase (decarboxylating)
Horse(100060355) glycine dehydrogenase (decarboxylating)
dog(481534) glycine dehydrogenase (decarboxylating)
chicken(374222) glycine dehydrogenase (decarboxylating)
sheep(101117476) glycine dehydrogenase (decarboxylating)
Domestic Rabbit(100343694) glycine dehydrogenase (decarboxylating)
domestic guinea pig(100714862) glycine dehydrogenase (decarboxylating)
naked mole-rat(101725465) glycine dehydrogenase (decarboxylating)
Summary: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010]

glycine-N-acyltransferase
Synonyms: ACGNAT CAT GAT
Species: Human GLYAT (10249), Mouse Glyat (107146), Rat Glyat (293779), cow GLYAT (281787), Horse GLYAT (100066603), Horse GLYAT (100068374), domestic cat GLYAT (101097840), dog GLYAT (483463), sheep GLYAT (101108685), naked mole-rat Glyat (101713466)
Gene ID:
Human(10249) glycine-N-acyltransferase
Mouse(107146) glycine-N-acyltransferase
Rat(293779) glycine-N-acyltransferase
cow(281787) glycine-N-acyltransferase
Horse(100066603) glycine-N-acyltransferase
Horse(100068374) glycine-N-acyltransferase
domestic cat(101097840) glycine-N-acyltransferase
dog(483463) glycine-N-acyltransferase
sheep(101108685) glycine-N-acyltransferase
naked mole-rat(101713466) glycine-N-acyltransferase
Summary: The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

glycine receptor, beta
Synonyms: HKPX2
Species: Human GLRB (2743), Mouse Glrb (14658), Rat Glrb (25456), chicken GLRB (422411), cow GLRB (281198), Horse GLRB (100061981), domestic cat GLRB (101088482), dog GLRB (475477), domestic guinea pig Glrb (100727431), naked mole-rat Glrb (101709956), sheep GLRB (101109484)
Gene ID:
Human(2743) glycine receptor, beta
Mouse(14658) glycine receptor, beta subunit
Rat(25456) glycine receptor, beta
chicken(422411) glycine receptor, beta
cow(281198) glycine receptor, beta
Horse(100061981) glycine receptor, beta
domestic cat(101088482) glycine receptor, beta
dog(475477) glycine receptor, beta
domestic guinea pig(100727431) glycine receptor, beta
naked mole-rat(101709956) glycine receptor, beta
sheep(101109484) glycine receptor, beta
Summary: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

glycine C-acetyltransferase
Synonyms: KBL
Species: Human GCAT (23464), Mouse Gcat (26912), Rat Gcat (366959), sheep GCAT (101102469), Domestic Rabbit GCAT (100353494), domestic guinea pig Gcat (100723646), naked mole-rat Gcat (101716933), Zebrafish gcat (402822), cow GCAT (319141), Horse GCAT (100069889), domestic cat GCAT (101098880), chicken GCAT (427905), dog GCAT (481262)
Gene ID:
Human(23464) glycine C-acetyltransferase
Mouse(26912) glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
Rat(366959) glycine C-acetyltransferase
sheep(101102469) glycine C-acetyltransferase
Domestic Rabbit(100353494) glycine C-acetyltransferase
domestic guinea pig(100723646) glycine C-acetyltransferase
naked mole-rat(101716933) glycine C-acetyltransferase
Zebrafish(402822) glycine C-acetyltransferase
cow(319141) glycine C-acetyltransferase
Horse(100069889) glycine C-acetyltransferase
domestic cat(101098880) glycine C-acetyltransferase
chicken(427905) glycine C-acetyltransferase
dog(481262) glycine C-acetyltransferase
Summary: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. [provided by RefSeq, Jan 2010]

glycine B complementing
Species: Human GLYB (2757)
Gene ID:
Human(2757) glycine B complementing

glycine receptor, alpha 4
Species: Human GLRA4 (441509), Mouse Glra4 (14657), Rat Glra4 (367912), sheep GLRA4 (101120810), domestic guinea pig Glra4 (100723095), naked mole-rat Glra4 (101700092), chicken GLRA4 (769706), dog GLRA4 (492035), domestic cat GLRA4 (101098122), cow GLRA4 (531678)
Gene ID:
Human(441509) glycine receptor, alpha 4
Mouse(14657) glycine receptor, alpha 4 subunit
Rat(367912) glycine receptor, alpha 4
sheep(101120810) glycine receptor, alpha 4
domestic guinea pig(100723095) glycine receptor, alpha 4
naked mole-rat(101700092) glycine receptor, alpha 4
chicken(769706) glycine receptor, alpha 4
dog(492035) glycine receptor, alpha 4
domestic cat(101098122) glycine receptor, alpha 4
cow(531678) glycine receptor, alpha 4
Summary: This gene encodes a protein which has a neurotransmitter-gated ion-channel ligand binding domain. The encoded protein is very similar to a mouse protein which is a subunit of the retinal glycine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

glycine N-methyltransferase
Species: Human GNMT (27232), Mouse Gnmt (14711), Rat Gnmt (25134), sheep GNMT (101111134), Domestic Rabbit GNMT (100009512), domestic guinea pig Gnmt (100717389), naked mole-rat Gnmt (101697457), Zebrafish gnmt (403338), chicken GNMT (769542), domestic cat GNMT (101083006), cow GNMT (538212), dog GNMT (474905)
Gene ID:
Human(27232) glycine N-methyltransferase
Mouse(14711) glycine N-methyltransferase
Rat(25134) glycine N-methyltransferase
sheep(101111134) glycine N-methyltransferase
Domestic Rabbit(100009512) glycine N-methyltransferase
domestic guinea pig(100717389) glycine N-methyltransferase
naked mole-rat(101697457) glycine N-methyltransferase
Zebrafish(403338) glycine N-methyltransferase
chicken(769542) glycine N-methyltransferase
domestic cat(101083006) glycine N-methyltransferase
cow(538212) glycine N-methyltransferase
dog(474905) glycine N-methyltransferase
Summary: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). [provided by RefSeq, Oct 2008]

glycine receptor, alpha 3
Species: Human GLRA3 (8001), Mouse Glra3 (110304), Rat Glra3 (114516), Zebrafish glra3 (192124), cow GLRA3 (614979), cow GLRA3 (541160), Horse GLRA3 (100060995), domestic cat GLRA3 (101087398), dog GLRA3 (486074), chicken GLRA3 (422568), domestic guinea pig Glra3 (100726006), naked mole-rat Glra3 (101715370), sheep GLRA3 (101119614), Domestic Rabbit GLRA3 (100358671)
Gene ID:
Human(8001) glycine receptor, alpha 3
Mouse(110304) glycine receptor, alpha 3 subunit
Rat(114516) glycine receptor, alpha 3
Zebrafish(192124) glycine receptor, alpha 3
cow(614979) glycine receptor, alpha 3
cow(541160) glycine receptor, alpha 3
Horse(100060995) glycine receptor, alpha 3
domestic cat(101087398) glycine receptor, alpha 3
dog(486074) glycine receptor, alpha 3
chicken(422568) glycine receptor, alpha 3
domestic guinea pig(100726006) glycine receptor, alpha 3
naked mole-rat(101715370) glycine receptor, alpha 3
sheep(101119614) glycine receptor, alpha 3
Domestic Rabbit(100358671) glycine receptor, alpha 3
Summary: The GLRA3 gene encodes the alpha-3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composed of ligand-binding alpha and structural beta polypeptides (Kingsmore et al., 1994 [PubMed 7894176]

glycine receptor, alpha 2
Synonyms: GLR
Species: Human GLRA2 (2742), Mouse Glra2 (237213), Rat Glra2 (24397), sheep GLRA2 (101121658), Domestic Rabbit GLRA2 (100348933), domestic guinea pig Glra2 (100715097), naked mole-rat Glra2 (101721983), Zebrafish glra2 (793646), chicken GLRA2 (772019), dog GLRA2 (491746), Horse GLRA2 (100050723), cow GLRA2 (537660), domestic cat GLRA2 (101090333)
Gene ID:
Human(2742) glycine receptor, alpha 2
Mouse(237213) glycine receptor, alpha 2 subunit
Rat(24397) glycine receptor, alpha 2
sheep(101121658) glycine receptor, alpha 2
Domestic Rabbit(100348933) glycine receptor, alpha 2
domestic guinea pig(100715097) glycine receptor, alpha 2
naked mole-rat(101721983) glycine receptor, alpha 2
Zebrafish(793646) glycine receptor alpha 2
chicken(772019) glycine receptor, alpha 2
dog(491746) glycine receptor, alpha 2
Horse(100050723) glycine receptor, alpha 2
cow(537660) glycine receptor, alpha 2
domestic cat(101090333) glycine receptor, alpha 2
Summary: The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

glycine receptor, alpha 1
Synonyms: HKPX1 STHE
Species: Human GLRA1 (2741), Mouse Glra1 (14654), Rat Glra1 (25674), Zebrafish glra1 (30676), cow GLRA1 (281783), Horse GLRA1 (100060055), domestic cat GLRA1 (101099022), chicken GLRA1 (427637), dog GLRA1 (489172), domestic guinea pig Glra1 (100271906), naked mole-rat Glra1 (101726680), sheep GLRA1 (101107093), Domestic Rabbit GLRA1 (100344552)
Gene ID:
Human(2741) glycine receptor, alpha 1
Mouse(14654) glycine receptor, alpha 1 subunit
Rat(25674) glycine receptor, alpha 1
Zebrafish(30676) glycine receptor, alpha 1
cow(281783) glycine receptor, alpha 1
Horse(100060055) glycine receptor, alpha 1
domestic cat(101099022) glycine receptor, alpha 1
chicken(427637) glycine receptor, alpha 1
dog(489172) glycine receptor, alpha 1
domestic guinea pig(100271906) glycine receptor, alpha 1 subunit
naked mole-rat(101726680) glycine receptor, alpha 1
sheep(101107093) glycine receptor, alpha 1
Domestic Rabbit(100344552) glycine receptor, alpha 1
Summary: The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]