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    Search term:"Yudin"

    11 matches found for Yudin

    Yudin and Coworkers Develop a New Line of MIDA Boronate Esters: Amphoteric Alpha-Boryl Aldehydes

    MIDA boronates, first developed by Burke and coworkers,1 have been shown to be effective in iterative cross-coupling sequences to provide access to myriad biaryl small molecules and complex natural products.1-2 A serendipitous discovery was made in the Andrei Yudin group.3 In the course of investiga...

    Andrei Yudin Group - Professor Product Portal

    Professor Product Portal Index Professor Andrei Yudin The Yudin laboratory is known for the development of amphoteric molecules and their application in synthesis. The corresponding reagents possess nucleophilic and electrophilic functional groups that do not prematurely react with each other. Over ...

    Discover Unprotected Amino Aldehydes from Professor Yudin

    Professor Andrei Yudin and co-workers have recently described the preparation of bench-stable, unprotected α-amino aldehydes.1These kinetically amphoteric molecules exist as dimers, and due to the strain of the aziridine ring, resist inter- and intramolecular iminium ion formation. Furthermore, the ...

    Heterocycle and Cyclic Peptide Formation with Pinc

    Related Articles • Chemical Synthesis Technology Spotlights Categories • Cyclizations • Drug Discovery • Isocyanides • Organic Synthesis • Yudin Isocyanides are widely used reagents in organic synthesis, with applications ranging from materials science to drug discovery. In the course of a chemical ...

    Unprotected Amino Aldehydes

    Aldrich ChemFiles 2010, 10.1, 16. Dr. Mark Redlich Dr. Mark Redlich Product Manager Email: mark.redlich@sial.com Professor Andrei Yudin and his students have recently described the preparation of bench-stable, unprotected a-amino aldehydes.1 These kinetically amphoteric molecules exist as dimers (eq...

    Aldrich Chemistry Webinar: Aziridine Aldehydes Reagents

    Aziridine Aldehydes as Reagents for Rapid and Chemoselective Synthesis of Complex Molecules Professor A. K. Yudin Chemistry Department University of Toronto Canada Watch Webinar Now! Overview: By taking advantage of orthogonally reactive functional groups, amphoteric molecules deliver more efficient...

    Alpha-Boryl Aldehydes - MIDA Boronates

    Alpha-boryl aldehydes have classically held potential to be highly useful intermediates, due to their amphoteric nature, in providing a platform for chemoselective sequences. However, these species have been difficult to isolate due to their low stability, and have typically been utilized only as t...

    Product Highlights for Organic and Inorganic Synthesis

    NEW! Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions NEW! Preparing Terminal Alkynes: Vinyl N,N-Diisopropylcarbamate for Stereospecific Alkynylation of Chiral Boronic Esters NEW! Dehydrogenation through Cooperative Base Metal Catalysis NEW! Trifunctional Probe Building Blocks NEW...

    Professor Product Portal

    The Professor Product Portal highlights the partnership between Sigma-Aldrich and academic investigators to commercialize research discoveries. It is our commitment to provide solutions for our customers by ensuring the rapid availability of cutting-edge catalysts, building blocks, and reagents from...

    Sigma-Aldrich Chemistry Webinars

    Sigma-Aldrich Chemistry Webinars are Web-based seminars describing the latest, innovative chemical synthesis technologies and products from Sigma-Aldrich Chemistry. These seminars are convenient to navigate, interactive, and accessed directly via your desktop browser. 2017 Current Topics in Bioconju...

    Suzuki Coupling

    • • Download PDF • C–C bond formation via the Suzuki–Miyaura reaction is one of the most powerful and thoroughly explored facets of Pdcatalyzed cross-coupling. The boron-based nucleophiles utilized in this reaction offer distinct advantages over other organometallic coupling reagents. Both boronic a...