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Search Results: 23
hepcidin antimicrobial peptide
Synonyms: HEPC HFE2B LEAP1 PLTR
Species: Human HAMP (57817), Mouse Hamp (84506), Rat Hamp (84604), domestic cat HAMP (101084332), Horse HAMP (100050728), cow HAMP (512301), dog HAMP (492281), sheep HAMP (100500730), domestic guinea pig Hamp (100733490), naked mole-rat Hamp (101700964)
Gene ID:
Human(57817) hepcidin antimicrobial peptide
Mouse(84506) hepcidin antimicrobial peptide
Rat(84604) hepcidin antimicrobial peptide
domestic cat(101084332) hepcidin antimicrobial peptide
Horse(100050728) hepcidin antimicrobial peptide
cow(512301) hepcidin antimicrobial peptide
dog(492281) hepcidin antimicrobial peptide
sheep(100500730) hepcidin antimicrobial peptide
domestic guinea pig(100733490) hepcidin antimicrobial peptide
naked mole-rat(101700964) hepcidin antimicrobial peptide
Summary: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008]

cathelicidin antimicrobial peptide
Synonyms: CAP-18 CAP18 CRAMP FALL-39 FALL39 LL37
Species: Human CAMP (820), Mouse Camp (12796), Rat Camp (316010), chicken CAMP (420407), dog CAMP (442947), domestic cat CAMP (100533978), cow CAMP (317650), domestic guinea pig Camp (100216361)
Gene ID:
Human(820) cathelicidin antimicrobial peptide
Mouse(12796) cathelicidin antimicrobial peptide
Rat(316010) cathelicidin antimicrobial peptide
chicken(420407) cathelicidin antimicrobial peptide
dog(442947) cathelicidin antimicrobial peptide
domestic cat(100533978) cathelicidin antimicrobial peptide
cow(317650) cathelicidin antimicrobial peptide
domestic guinea pig(100216361) cathelicidin antimicrobial peptide
Summary: This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The encoded protein has several functions in addition to antimicrobial activity, including cell chemotaxis, immune mediator induction and inflammatory response regulation. [provided by RefSeq, Aug 2011]

liver expressed antimicrobial peptide 2
Synonyms: LEAP-2
Species: Human LEAP2 (116842), Mouse Leap2 (259301), Rat Leap2 (497901), chicken LEAP2 (414338), cow LEAP2 (282270), domestic cat LEAP2 (101097296), dog LEAP2 (609750), sheep LEAP2 (101121678), Domestic Rabbit LEAP2 (100328728), domestic guinea pig Leap2 (100135569), naked mole-rat Leap2 (101712195)
Gene ID:
Human(116842) liver expressed antimicrobial peptide 2
Mouse(259301) liver-expressed antimicrobial peptide 2
Rat(497901) liver-expressed antimicrobial peptide 2
chicken(414338) liver expressed antimicrobial peptide 2
cow(282270) liver expressed antimicrobial peptide 2
domestic cat(101097296) liver expressed antimicrobial peptide 2
dog(609750) liver expressed antimicrobial peptide 2
sheep(101121678) liver expressed antimicrobial peptide 2
Domestic Rabbit(100328728) liver expressed antimicrobial peptide 2
domestic guinea pig(100135569) liver expressed antimicrobial peptide 2
naked mole-rat(101712195) liver expressed antimicrobial peptide 2
Summary: LEAP2 is a cysteine-rich cationic antimicrobial peptide (Krause et al., 2003 [PubMed 12493837]

Species: Mouse Hamp2 (66438), Zebrafish hamp2 (594858)
Gene ID:
Mouse(66438) hepcidin antimicrobial peptide 2
Zebrafish(594858) hepcidin antimicrobial peptide 2

Species: Human LAP (7939), fruit fly lap (40863), cow LAP (403090)
Gene ID:
Human(7939) Laryngeal adductor paralysis
fruit fly(40863) like-AP180
cow(403090) lingual antimicrobial peptide

ribonuclease, RNase A family, 7
Species: Human RNASE7 (84659), cow RNASE7 (538679), cow RNASE7 (783267), domestic guinea pig Rnase7 (100714967), domestic cat RNASE7 (101092691)
Gene ID:
Human(84659) ribonuclease, RNase A family, 7
cow(538679) ribonuclease, RNase A family, 7
cow(783267) ribonuclease, RNase A family, 7
domestic guinea pig(100714967) ribonuclease, RNase A family, 7
domestic cat(101092691) ribonuclease, RNase A family, 7
Summary: RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity (Harder and Schroder, 2002 [PubMed 12244054]

granulysin
Synonyms: 519 D2S69E LAG-2 LAG2 NKG5 TLA519
Species: Human GNLY (10578), cow GNLY (404173), sheep GNLY (100125622)
Gene ID:
Human(10578) granulysin
cow(404173) granulysin
sheep(100125622) granulysin
Summary: The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

peptidase inhibitor 3, skin-derived
Synonyms: ESI SKALP WAP3 WFDC14 cementoin
Species: Human PI3 (5266), cow PI3 (407165), cow PI3 (783871), domestic cat PI3 (101090932), dog PI3 (477241)
Gene ID:
Human(5266) peptidase inhibitor 3, skin-derived
cow(407165) peptidase inhibitor 3, skin-derived (SKALP)
cow(783871) peptidase inhibitor 3, skin-derived (SKALP)
domestic cat(101090932) peptidase inhibitor 3, skin-derived
dog(477241) peptidase inhibitor 3, skin-derived
Summary: This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2008]

defensin, beta 103B
Synonyms: BD-3 DEFB103 DEFB3 HBD3 HBP3
Species: Human DEFB103B (55894)
Gene ID:
Human(55894) defensin, beta 103B
Summary: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. [provided by RefSeq, Jul 2008]

defensin, beta 118
Synonyms: C20orf63 DEFB-18 ESC42 ESP13.6
Species: Human DEFB118 (117285), cow DEFB118 (100336211), domestic guinea pig Defb118 (101787756), naked mole-rat Defb118 (101718270)
Gene ID:
Human(117285) defensin, beta 118
cow(100336211) defensin, beta 118
domestic guinea pig(101787756) defensin, beta 118
naked mole-rat(101718270) defensin, beta 118
Summary: This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Dec 2010]