EMAIL THIS PAGE TO A FRIEND


Product Category
Organism
Mouse
Human
Rat
cow
dog
domestic guinea pig
chicken
domestic cat
naked mole-rat
sheep
Zebrafish
Horse
Domestic Rabbit
fruit fly
Thale Cress
Search Results: 27
Species: Mouse Clas4 (100036371)
Gene ID:
Mouse(100036371) carcinogen-induced lung adenoma susceptibility 4

Species: Mouse Clas2 (100035688)
Gene ID:
Mouse(100035688) carcinogen-induced lung adenoma susceptibility 2

Species: Mouse Clas3 (100035386)
Gene ID:
Mouse(100035386) carcinogen-induced lung adenoma susceptibility 3

arylacetamide deacetylase
Synonyms: CES5A1 DAC
Species: Human AADAC (13), Mouse Aadac (67758), Rat Aadac (57300), dog AADAC (477115), Horse AADAC (100056411), cow AADAC (519557), domestic cat AADAC (101096344), domestic guinea pig Aadac (100723674), naked mole-rat Aadac (101706394)
Gene ID:
Human(13) arylacetamide deacetylase
Mouse(67758) arylacetamide deacetylase (esterase)
Rat(57300) arylacetamide deacetylase
dog(477115) arylacetamide deacetylase
Horse(100056411) arylacetamide deacetylase
cow(519557) arylacetamide deacetylase (esterase)
domestic cat(101096344) arylacetamide deacetylase
domestic guinea pig(100723674) arylacetamide deacetylase
naked mole-rat(101706394) arylacetamide deacetylase
Summary: Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]

glutathione S-transferase mu 2 (muscle)
Synonyms: GST4 GSTM GSTM2-2 GTHMUS
Species: Human GSTM2 (2946), Mouse Gstm2 (14863), Rat Gstm2 (24424), sheep GSTM2 (100294593), Domestic Rabbit GSTM2 (100009073), domestic guinea pig Gstm2 (100379537), domestic guinea pig Gstm2 (100732167), chicken GSTM2 (395976), cow GSTM2 (615537)
Gene ID:
Human(2946) glutathione S-transferase mu 2 (muscle)
Mouse(14863) glutathione S-transferase, mu 2
Rat(24424) glutathione S-transferase mu 2
sheep(100294593) glutathione S-transferase mu 2 (muscle)
Domestic Rabbit(100009073) glutathione S-transferase mu 2 (muscle)
domestic guinea pig(100379537) glutathione S-transferase, mu 2
domestic guinea pig(100732167) glutathione S-transferase mu 2 (muscle)
chicken(395976) glutathione S-transferase mu 2 (muscle)
cow(615537) glutathione S-transferase M2
Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]

glutathione S-transferase mu 1
Synonyms: GST1 GSTM1-1 GSTM1a-1a GSTM1b-1b GTH4 GTM1 H-B MU MU-1
Species: Human GSTM1 (2944), Mouse Gstm1 (14862), Rat Gstm1 (24423), cow GSTM1 (327709), cow GSTM1 (783879), domestic guinea pig Gstm1 (100731426)
Gene ID:
Human(2944) glutathione S-transferase mu 1
Mouse(14862) glutathione S-transferase, mu 1
Rat(24423) glutathione S-transferase mu 1
cow(327709) glutathione S-transferase M1
cow(783879) glutathione S-transferase mu 1
domestic guinea pig(100731426) glutathione S-transferase mu 1
Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]

glutathione S-transferase alpha 5
Species: Human GSTA5 (221357), Rat Gsta5 (494499), Rat Gsta5 (494500), cow GSTA5 (521685)
Gene ID:
Human(221357) glutathione S-transferase alpha 5
Rat(494499) glutathione S-transferase alpha 5
Rat(494500) glutathione S-transferase Yc2 subunit
cow(521685) glutathione S-transferase alpha 5
Summary: The glutathione S-transferases (GST; EC 2.5.1.18) catalyze the conjugation of reduced glutathiones and a variety of electrophiles, including many known carcinogens and mutagens. The cytosolic GSTs belong to a large superfamily, with members located on different chromosomes. For additional information on GSTs, see GSTA1 (MIM 138359).[supplied by OMIM, Sep 2008]

glutathione S-transferase omega 1
Synonyms: GSTO 1-1 GSTTLp28 P28 SPG-R
Species: Human GSTO1 (9446), Mouse Gsto1 (14873), Rat Gsto1 (114846), Zebrafish gsto1 (436894), cow GSTO1 (505642), domestic cat GSTO1 (101097351), fruit fly GstO1 (38975), dog GSTO1 (477813), chicken GSTO1 (423881), domestic guinea pig Gsto1 (100720637), naked mole-rat Gsto1 (101712139)
Gene ID:
Human(9446) glutathione S-transferase omega 1
Mouse(14873) glutathione S-transferase omega 1
Rat(114846) glutathione S-transferase omega 1
Zebrafish(436894) glutathione S-transferase omega 1
cow(505642) glutathione S-transferase omega 1
domestic cat(101097351) glutathione S-transferase omega 1
fruit fly(38975) Glutathione S transferase O1
dog(477813) glutathione S-transferase omega 1
chicken(423881) glutathione S-transferase omega 1
domestic guinea pig(100720637) glutathione S-transferase omega 1
naked mole-rat(101712139) glutathione S-transferase omega 1
Summary: The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

glutathione S-transferase omega 2
Synonyms: GSTO 2-2 bA127L20.1
Species: Human GSTO2 (119391), Mouse Gsto2 (68214), Rat Gsto2 (309465), domestic guinea pig Gsto2 (100720364), naked mole-rat Gsto2 (101712717), sheep GSTO2 (101115496), Zebrafish gsto2 (492500), cow GSTO2 (613905), domestic cat GSTO2 (101090141), dog GSTO2 (477814), fruit fly GstO2 (38974)
Gene ID:
Human(119391) glutathione S-transferase omega 2
Mouse(68214) glutathione S-transferase omega 2
Rat(309465) glutathione S-transferase omega 2
domestic guinea pig(100720364) glutathione S-transferase omega 2
naked mole-rat(101712717) glutathione S-transferase omega 2
sheep(101115496) glutathione S-transferase omega 2
Zebrafish(492500) glutathione S-transferase omega 2
cow(613905) glutathione S-transferase omega 2
domestic cat(101090141) glutathione S-transferase omega 2
dog(477814) glutathione S-transferase omega 2
fruit fly(38974) Glutathione S transferase O2
Summary: The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

glutathione S-transferase alpha 2
Synonyms: GST2 GSTA2-2 GTA2 GTH2
Species: Human GSTA2 (2939), Mouse Gsta2 (14858), Rat Gsta2 (24422), domestic cat GSTA2 (101096317), cow GSTA2 (281805)
Gene ID:
Human(2939) glutathione S-transferase alpha 2
Mouse(14858) glutathione S-transferase, alpha 2 (Yc2)
Rat(24422) glutathione S-transferase alpha 2
domestic cat(101096317) glutathione S-transferase alpha 2
cow(281805) glutathione S-transferase alpha 2
Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]