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Search Results: 9
glyoxalase I
Synonyms: GLOD1 GLYI
Species: Human GLO1 (2739), Mouse Glo1 (109801), Rat Glo1 (294320), Zebrafish glo1 (368213), domestic cat GLO1 (101085123), cow GLO1 (540335), dog GLO1 (474894), chicken GLO1 (421428), sheep GLO1 (101102520), domestic guinea pig Glo1 (100726491), naked mole-rat Glo1 (101699804)
Gene ID:
Human(2739) glyoxalase I
Mouse(109801) glyoxalase 1
Rat(294320) glyoxalase 1
Zebrafish(368213) glyoxalase 1
domestic cat(101085123) glyoxalase I
cow(540335) glyoxalase I
dog(474894) glyoxalase I
chicken(421428) glyoxalase I
sheep(101102520) glyoxalase I
domestic guinea pig(100726491) glyoxalase I
naked mole-rat(101699804) glyoxalase I
Summary: The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]

aldo-keto reductase family 1, member D1
Synonyms: 3o5bred CBAS2 SRD5B1
Species: Human AKR1D1 (6718), Mouse Akr1d1 (208665), Rat Akr1d1 (192242), chicken AKR1D1 (418107), dog AKR1D1 (482711), dog AKR1D1 (491379), domestic cat AKR1D1 (101100551), cow AKR1D1 (513855), domestic guinea pig Akr1d1 (100713034), naked mole-rat Akr1d1 (101716388), sheep AKR1D1 (101103641), Domestic Rabbit AKR1D1 (100008612)
Gene ID:
Human(6718) aldo-keto reductase family 1, member D1
Mouse(208665) aldo-keto reductase family 1, member D1
Rat(192242) aldo-keto reductase family 1, member D1
chicken(418107) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
dog(482711) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
dog(491379) 3-oxo-5-beta-steroid 4-dehydrogenase-like
domestic cat(101100551) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
cow(513855) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
domestic guinea pig(100713034) aldo-keto reductase family 1, member D1
naked mole-rat(101716388) aldo-keto reductase family 1, member D1
sheep(101103641) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
Domestic Rabbit(100008612) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
Summary: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]

ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Synonyms: UCH-L3
Species: Human UCHL3 (7347), Mouse Uchl3 (50933), Rat Uchl3 (498560), cow UCHL3 (520170), sheep UCHL3 (101123568), domestic guinea pig Uchl3 (100728179), naked mole-rat Uchl3 (101718538), Zebrafish uchl3 (554104), chicken UCHL3 (395626), dog UCHL3 (476947), domestic cat UCHL3 (101083135)
Gene ID:
Human(7347) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Mouse(50933) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Rat(498560) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
cow(520170) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
sheep(101123568) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
domestic guinea pig(100728179) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
naked mole-rat(101718538) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Zebrafish(554104) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chicken(395626) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
dog(476947) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
domestic cat(101083135) ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Summary: The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

interleukin 4 induced 1
Synonyms: FIG1 LAAO LAO
Species: Human IL4I1 (259307), Mouse Il4i1 (14204), Rat Il4i1 (308575), sheep IL4I1 (101114462), domestic guinea pig Il4i1 (100722053), naked mole-rat Il4i1 (101710424), chicken IL4I1 (417039), cow IL4I1 (100138517), domestic cat IL4I1 (101100683), dog IL4I1 (484371)
Gene ID:
Human(259307) interleukin 4 induced 1
Mouse(14204) interleukin 4 induced 1
Rat(308575) interleukin 4 induced 1
sheep(101114462) interleukin 4 induced 1
domestic guinea pig(100722053) interleukin 4 induced 1
naked mole-rat(101710424) interleukin 4 induced 1
chicken(417039) interleukin 4 induced 1
cow(100138517) interleukin 4 induced 1
domestic cat(101100683) interleukin 4 induced 1
dog(484371) interleukin 4 induced 1
Summary: This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

ecto-NOX disulfide-thiol exchanger 2
Synonyms: APK1 COVA1 tNOX
Species: Human ENOX2 (10495), Mouse Enox2 (209224), Rat Enox2 (302817), Zebrafish enox2 (566327), chicken ENOX2 (422142), domestic cat ENOX2 (101083495), Horse ENOX2 (100058391), dog ENOX2 (481050), cow ENOX2 (100336550), domestic guinea pig Enox2 (100728927), naked mole-rat Enox2 (101704048)
Gene ID:
Human(10495) ecto-NOX disulfide-thiol exchanger 2
Mouse(209224) ecto-NOX disulfide-thiol exchanger 2
Rat(302817) ecto-NOX disulfide-thiol exchanger 2
Zebrafish(566327) ecto-NOX disulfide-thiol exchanger 2
chicken(422142) ecto-NOX disulfide-thiol exchanger 2
domestic cat(101083495) ecto-NOX disulfide-thiol exchanger 2
Horse(100058391) ecto-NOX disulfide-thiol exchanger 2
dog(481050) ecto-NOX disulfide-thiol exchanger 2
cow(100336550) ecto-NOX disulfide-thiol exchanger 2
domestic guinea pig(100728927) ecto-NOX disulfide-thiol exchanger 2
naked mole-rat(101704048) ecto-NOX disulfide-thiol exchanger 2
Summary: The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

vaccinia related kinase 3
Species: Human VRK3 (51231), Mouse Vrk3 (101568), Rat Vrk3 (361565), Zebrafish vrk3 (541443), chicken VRK3 (770440), domestic cat VRK3 (101092656), dog VRK3 (484367), cow VRK3 (520302), sheep VRK3 (101109637), naked mole-rat Vrk3 (101705633), domestic guinea pig Vrk3 (100721045)
Gene ID:
Human(51231) vaccinia related kinase 3
Mouse(101568) vaccinia related kinase 3
Rat(361565) vaccinia related kinase 3
Zebrafish(541443) vaccinia related kinase 3
chicken(770440) vaccinia related kinase 3
domestic cat(101092656) vaccinia related kinase 3
dog(484367) vaccinia related kinase 3
cow(520302) vaccinia related kinase 3
sheep(101109637) vaccinia related kinase 3
naked mole-rat(101705633) vaccinia related kinase 3
domestic guinea pig(100721045) vaccinia related kinase 3
Summary: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
Synonyms: MSTP042 NBP1 SFD SFDalpha SFDbeta VMA13
Species: Human ATP6V1H (51606), Mouse Atp6v1h (108664), Rat Atp6v1h (297797), naked mole-rat Atp6v1h (101710987), domestic guinea pig Atp6v1h (100716527), sheep ATP6V1H (101113504), Zebrafish atp6v1h (286779), chicken ATP6V1H (426199), cow ATP6V1H (282657), dog ATP6V1H (486953), domestic cat ATP6V1H (101095225)
Gene ID:
Human(51606) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
Mouse(108664) ATPase, H+ transporting, lysosomal V1 subunit H
Rat(297797) ATPase, H+ transporting, lysosomal V1 subunit H
naked mole-rat(101710987) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
domestic guinea pig(100716527) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
sheep(101113504) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
Zebrafish(286779) ATPase, H+ transporting, lysosomal, V1 subunit H
chicken(426199) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
cow(282657) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
dog(486953) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
domestic cat(101095225) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

lactase-like
Synonyms: KLG KLPH
Species: Human LCTL (197021), Mouse Lctl (235435), Rat Lctl (315750), domestic guinea pig Lctl (100719387), naked mole-rat Lctl (101714667), sheep LCTL (101102566), domestic cat LCTL (101101641), cow LCTL (518599), Horse LCTL (100053000), dog LCTL (487611)
Gene ID:
Human(197021) lactase-like
Mouse(235435) lactase-like
Rat(315750) lactase-like
domestic guinea pig(100719387) lactase-like
naked mole-rat(101714667) lactase-like
sheep(101102566) lactase-like
domestic cat(101101641) lactase-like
cow(518599) lactase-like
Horse(100053000) lactase-like
dog(487611) lactase-like
Summary: This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

phospholipase A2, group IIA (platelets, synovial fluid)
Synonyms: MOM1 PLA2 PLA2B PLA2L PLA2S PLAS1 sPLA2
Species: Human PLA2G2A (5320), Mouse Pla2g2a (18780), Rat Pla2g2a (29692), chicken PLA2G2A (426748), domestic guinea pig Pla2g2a (100135599), cow PLA2G2A (507201), cow PLA2G2A (521383)
Gene ID:
Human(5320) phospholipase A2, group IIA (platelets, synovial fluid)
Mouse(18780) phospholipase A2, group IIA (platelets, synovial fluid)
Rat(29692) phospholipase A2, group IIA (platelets, synovial fluid)
chicken(426748) phospholipase A2, group IIA (platelets, synovial fluid)
domestic guinea pig(100135599) phospholipase A2, group IIA (platelets, synovial fluid)
cow(507201) phospholipase A2, group IIA (platelets, synovial fluid)
cow(521383) phospholipase A2, group IIA (platelets, synovial fluid)
Summary: The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]