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Search Results: 1
paraoxonase 1
Synonyms: ESA MVCD5 PON
Species: Human PON1 (5444), Mouse Pon1 (18979), Rat Pon1 (84024), Zebrafish pon1 (447803), dog PON1 (475234), domestic cat PON1 (101091522), cow PON1 (523798), sheep PON1 (101116983), domestic guinea pig Pon1 (100721268), naked mole-rat Pon1 (101696947), Domestic Rabbit PON1 (100009133)
Gene ID:
Human(5444) paraoxonase 1
Mouse(18979) paraoxonase 1
Rat(84024) paraoxonase 1
Zebrafish(447803) paraoxonase 1
dog(475234) paraoxonase 1
domestic cat(101091522) paraoxonase 1
cow(523798) paraoxonase 1
sheep(101116983) paraoxonase 1
domestic guinea pig(100721268) paraoxonase 1
naked mole-rat(101696947) paraoxonase 1
Domestic Rabbit(100009133) paraoxonase 1
Summary: The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq, Oct 2008]