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147 matches found for bacterial_conjugations

Safe Manufacture of Antibody Drug Conjugates

Although antibody-drug conjugates show promise in the development of effective cancer therapies, there are still a variety of challenges involved in enabling the safe manufacture of these hazardous drugs. Antibody-drug conjugates (ADCs) – anti-cancer drugs which combine the specificity of a monoclon...

Enzyme Explorer Product Application Index for Superoxide Dismutase

Superoxide Dismutase (SOD) catalyzes the reduction of superoxide anions to hydrogen peroxide. It plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion, which inactivates NO to form peroxynitrite. Therefore...

Development of Small Molecule Donors for Solution-Processed Organic Solar Cells

Abby-Jo Payne and Gregory C. Welch Dalhousie University, Department of Chemistry 6274 Coburg Road, Halifax, Nova Scotia, Canada B3H 4R2 Email: gregory.welch@dal.ca Solution-processed organic photovoltaic devices (OPVs) have emerged as a promising clean energy generating technology due to their ease ...

温度・pH応答性PNIPAMポリマー

Gangadhar Panambur, Ilya Koltover and Scott Batcheller Aldrich Materials Science, Milwaukee, WI. 刺激応答性ポリマー 刺激応答性ポリマーは、「スマート」ポリマーもしくは「環境応答性」ポリマーとしても知られ、周囲の環境変化によってそのミクロ構造が急激に変化します。外部刺激(熱、pH、イオン強度、磁場、電場、光、超音波、化学種など)が環境の変化を引き起こし、生じた巨視的変化は可逆的であるため、そのきっかけとなる要因がなくなれば、システムは初期状態に戻ることが可能です。刺激応答性ポリマーはその物理的形状に...

Polymersomes for Drug Delivery

Department of Chemical Engineering, Melbourne School of Engineering The University of Melbourne, Parkville 3010 Victoria, Australia *Email: luke.connal@unimelb.edu.au The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine t...

NTz Building Blocks for Organic Semiconductors

Fax: +81-48-462-1473, E-mail: takimiya@riken.jp The field of organic electronics has emerged as the next-generation technology potentially enabling ultra-thin, large-area, and/or flexible devices, consisting of organic field-effect transistors (OFETs), organic light-emitting diodes (OLEDs), and orga...

NIPAM based Polymers

Gangadhar Panambur, Ilya Koltover and Scott Batcheller MilliporeSigma, 6000 N. Teutonia Milwaukee, WI 53209 Stimuli-responsive Polymers Stimuli-responsive polymers, also known as “smart” polymers or “environmentally sensitive” polymers, undergo rapid changes in their microstructure from a hydrophili...

ZooMAb® Antibodies Frequently Asked Questions

Related Links • View all ZooMAb® Antibody Products • ZooMAb® Antibodies • ZooMAb® Antibodies Technical Article • Antibody Explorer • Highly Cited Antibodies • Antibody Guarantee 1. Why are these called ZooMAb® antibodies? 2. How do I know what species my ZooMAb® antibody is? 3. How many species do y...

Competent Cell Selection & E. coli Markers Guide

Transformation • Introduction to Bacterial Transformation • Introduction to Yeast Transformation • Introduction to Blue-white Screening • Transformation Protocols for Bacteria • Transformation Protocols for Yeast Related Resources • Molecular Biology Handbook • E. coli genotypes • Cloning & Expressi...

Plant Immunochemistry Product Lines

Plant Immunochemistry offers an extensive line of products for bioassay and reagents for antibody detection. Plant Immunochemistry covers many plant areas including plant antibodies. Conveniently packaged, rigorously assayed and supported by the leading supplier for Plant Immunochemistry research, o...

OEM Services

Your trusted clinical diagnostics contract manufacturing partner Key Technologies • Molecular Amplification • Oligos, probes, amidites • DNA/RNA enzymes • Molecular-grade buffers, formulations • Nucleic acid purification • Conjugation • Large molecules to beads/resins • Linkage chemistry • Detection...

Smart Oligonucleotide Delivery by Multifunctional Block Copolymers

Related Content • Microfluidic-Assisted Manufacturing of Materials for Nanomedicine • Three-Dimensional Bioprinting for Tissue and Disease Modeling • Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting • Applications of Glucose Polymers in the Synthesis of Diagnostic and Drug Delivery Nano...

Turmeric, Curcumin (Curcuma longa) | Plant Profiler

Synonyms / Common Names / Related Terms Amomoum curcuma, anlatone (constituent), ar-tumerone, CUR, Curcuma, Curcuma aromatica, Curcuma aromatica Salisbury, Curcuma domestica, Curcuma domestica Valet, Curcuma longa, Curcuma longa Linn., Curcuma longa rhizoma, curcuma oil, curcumin, diferuloylmethane,...

References for Labeling Antibodies

Labeling Antibodies with Alkaline Phosphatase Labeling Antibodies with Fluorochromes FITC TRITC Biotin Labeling Antibodies with Horseradish Peroxidase Glutaraldehyde Periodate Labeling Antibodies with Alkaline Phosphatase Voller, A., et al., Bull. World Health Organ., 53, 55 (1976). Harlow, E., and ...

At-line monitoring of cell cultures: Rapid cytometric evaluation of cellular physiology

N.T. Mukwena1, F. Veraitch1, S. Santhalingham1, M. Al-Rubeai1 and P. Goix2 1Department of Chemical Engineering, University of Birmingham, Birmingham B15 2TT, UK 2Guava Technologies, Inc., 25801 Industrial Blvd., Hayward, CA 94545, USA, www.guavatechnologies.com Mammalian cell culture processes face ...

高薬理活性API(医薬原体)・細胞毒性物質

高薬理活性医薬原体(HPAPI)受託製造のリーディングカンパニー 高薬理活性医薬原体(HPAPI)は、従来のAPIより少量で高い活性がありますが、その活性のため、取扱いは容易ではありません。SAFCはバイオコンジュゲートや発酵生産技術などの高い技術力で、急成長するHPAPI製造分野のリーディングカンパニーとして製薬メーカーをサポートしています。 高薬理活性API・細胞毒性物質製造サービス • 15年にわたる、HPAPIの開発・製造からカテゴリー4対応までの幅広いサポート実績 • 特殊な封じ込め技術を採用した専用のSafebridge®認証施設 • 広範な製造能力 • 高度な訓練を受けたスタッフ...

Enzyme Explorer Drug Metabolism Tech Review

Multi-Drug Resistance in Cancer - Role of ABC Transporter Proteins Balázs Sarkadi1, Gergely Szakás1,2 and András Váradi3 1. National Medical Center, Institute of Hematology and Immunology, Budapest, Hungary 2. National Cancer Institute, NIH, Bethesda, MD, USA 3. Institute of Enzymology, Hungarian Ac...

Stem Cell Models for Drug Discovery and Metabolomics Research

Product Manager robert.gates@sial.com Over the past three decades non-cellular and cellular systems have supplanted whole animal studies for the preliminary screening of drug candidates and well as for initial drug metabolism and toxicology studies. In 1991 inadequate metabolic and pharmacokinetic p...

Nathan Luedtke Group – Products available at Aldrich from the Luedtke Laboratory

Professor Product Portal Index Professor Nathan Luedtke Metabolic incorporation of a bioorthogonal functional group (e.g. alkyne, azide, alkene, etc.) into cellular DNA can be achieved by simply adding a synthetic nucleoside to the nutritional media of cells or whole animals. Intracellular enzymes i...

Polytriarylamine Semiconductors

• Flexink Limited - www.flexink.co.uk Southampton, UK E-mail: sales@flexink.co.uk Organic electronics is an emerging scientific field of potentially huge technological and commercial relevance1, and is an increasingly ubiquitous research activity globally. One important area is the development of or...

Light-Emitting Polymers

Related eTool • OLED eFabricator • • Download PDF • Department of Materials Science and Engineering, California NanoSystems Institute, and Henry Samuli School of Engineering and Applied Science, UCLA Conjugated polymers with long range p-electron delocalization behave as processable organic “metals”...

Properties and Applications of Functionalized Graphene Oxide

1Claremont University, Keck Graduate Institute, School of Applied Life Sciences Claremont, CA 91711, USA 2Keck Science Department, Claremont McKenna College, Claremont, CA, 91711, USA 3Keck Science Department, Pitzer College, Claremont, CA, 91711, USA *E-mail: Kiana_Aran@kgi.edu Article Sections • I...

Poly(2-Oxazoline)S: The Versatile Polymer Platform for Biomedicine

Victor R. de la Rosa,1 An Van Den Bulcke,2 and Richard Hoogenboom1* 1Supramolecular Chemistry Group, Department of Organic and Macromolecular Chemistry Ghent University, Krijgslaan 281-S4, 9000 Ghent, Belgium 2ChemTech, Department of Organic and Macromolecular Chemistry, Ghent University Krijgslaan ...

ドラッグデリバリーにおける高分子科学の手法

【高分子材料を用いたドラッグデリバリーシステム(DDS)研究に最適】 ドラッグデリバリーにおいて、溶解性の向上・放出制御・標的志向化に重要な役割を担う高分子科学のアプリケーションと実験手順を紹介します(英語版)。 • DDS研究者によるプロトコール紹介 • 低分子、核酸、タンパク質の送達 • キーテクノロジー ○ 薬剤コンジュゲートと PEGylation ○ 生分解性ナノ粒子とミセル ○ RAFT重合を利用したADCのための高分子キャリア ○ デンドロン ○ 応答性ドラッグデリバリーシステム ○ 核酸デリバリーのためのポリマー材料 PDFダウンロード (5.4MB) 目次 Polymer M...

Protocol for Conjugating NHS-Ester Modifications to Amino-Labeled Oligonucleotides

This protocol is for conjugating NHS-ester modifications, such as TxRd (Sulforhodamine 101-X) (protocol is effective for most NHS-ester modifications), to an oligonucleotide with an amino label, such as 5'-Amino-Modifier C6 (Figure 1). Since TxRd (Sulforhodamine 101-X) and several other modification...

Understanding and Successfully Applying Materials for Dye-Sensitized Solar Cells

Hans Desilvestro, Yanek Hebting, Mikael Khan, Damion Milliken Dyesol, Queanbeyan NSW 2620, Australia Email: yhebting@dyesol.com While dye sensitization as the basis for color photography has been accepted for a very long time,1 attempts to use this principle for the conversion of solar light to elec...

New Products for Detection Applications

Isoelectric focusing (IEF) is a powerful analytical tool for the separation of proteins. In order to ensure the high performance of analysis, isoelectric point (pI) standards are needed. In addition to classical protein based standards, low molecular weight compounds have been developed and succesfu...

Smart Oligonucleotide Delivery by Multifunctional Block Copolymers

Related Content • Microfluidic-Assisted Manufacturing of Materials for Nanomedicine • Three-Dimensional Bioprinting for Tissue and Disease Modeling • Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting • Applications of Glucose Polymers in the Synthesis of Diagnostic and Drug Delivery Nano...

金ナノ粒子へのタンパク質コンジュゲーション

Article outline • はじめに • 方法例Ⅰ:受動的吸着法による未修飾金ナノ粒子への抗体のコンジュゲーション • 方法例Ⅱ:カルボキシル化金ナノ粒子への抗体のコンジュゲーション • 方法例Ⅲ:NHS活性化金ナノ粒子への抗体のコンジュゲーション • 方法例Ⅳ:マレイミド活性化金ナノ粒子への抗体のコンジュゲーション Benny Pacheco Cytodiagnostics, 919 Fraser Drive, Unit 11, Burlington, ON L7L 4X8, Canada Nanomaterial Bioconjugation Techniques(ナノ粒子表面修飾...

Customer-Driven Innovation: Collaborate with us to drive your assay development

We understand that it can be challenging to bring an assay to market and that your resources can be stretched thin while optimizing reagents, samples and systems. Our Customer-Driven Innovation (CDI) program aims to help you by putting our R&D resources into your hands. From creating a better raw ma...