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133 matches found for bacterial_conjugations

Triazolylphenylglyoxal Reagents: Arginine-Directed Bioconjugation

Chemical ligation strategies are widely utilized for the modification of biological macromolecules in biotechnology and medicine and for the development of functional materials. In particular, reagents that can modify the surface of proteins, typically through reactive side chains, have found broad ...

Development of Small Molecule Donors for Solution-Processed Organic Solar Cells

Abby-Jo Payne and Gregory C. Welch Dalhousie University, Department of Chemistry 6274 Coburg Road, Halifax, Nova Scotia, Canada B3H 4R2 Email: gregory.welch@dal.ca Solution-processed organic photovoltaic devices (OPVs) have emerged as a promising clean energy generating technology due to their ease ...

Complete Solutions for IVD ELISA Manufacturers – From Raw Materials to Risk Mitigation

Your Partner from Concept to Clinic Simplify ELISA assay development and manufacture with a partner who understands the IVD market Accelerate your time to market with our fit-for-use products which offer the quality, consistency and documentation necessary for every step of your IVD development and ...

Partial PROTACs for Targeted Protein Degradation

An emerging strategy in drug discovery to access difficult-to-treat diseases is targeted protein degradation. While traditional small-molecule or antibody drugs may only allow access to ~20% of the proteome, degradation techniques may open the door to the other 80%.1 The molecules used in these appr...

Enzyme Explorer Lectin Index

We have the largest selection of lectins and lectin conjugates available, with over 100 products from over 35 sources. Backed by quality and service you’ve come to expect, we offer lectins for all your life science applications, including: • Histochemical Studies • Lymphocyte Subpopulations Studies ...

Authenticated Colorectal Cancer Cell Lines for Cancer Research

Related Links • Cell Culture • ECACC Cell Lines • Protocols for ECACC Cell Lines • Browse Colorectal Cancer Cell Lines Related Articles • Exploring Colon Cancer with Prestige Antibodies® • MSI Testing and IHC • Colorectal Cancer and Immunohistochemistry • Breast Cancer Cell Lines • Liver Cancer Cell...

Molybdenum Disulfide: Understanding Hydrogen Evolution Catalysis

Linyou Cao Department of Materials Science and Engineering Department of Physics North Carolina State University, Raleigh, NC, USA Email: lcao2@ncsu.edu The production of hydrogen by catalytic water splitting is important for a wide range of industries including renewable energy petroleum refining a...

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Jiayu Leong,1 Liam Grover,2 Hyunjoon Kong1* 1Department of Chemical and Biomolecular Engineering University of Illinois, Urbana-Champaign, IL 61801 USA 2University of Birmingham, UK *Email: hjkong06@illinois.edu Collagen molecules play a critical role in tissue architecture and strength, and in cell...

Glycosyltransferases: Tools for Synthesis and Modification of Glycans

• • Download PDF • The presence of multiple functional groups and stereocenters in complex carbohydrates makes them challenging targets for the organic chemist. Chemical synthesis research has not yielded robust, automated protocols comparable to those developed for the preparation of peptides and o...

Asymmetric Polymerization in a Chiral Liquid Crystal Reaction Field

• • Download PDF • Department of Polymer Chemistry, Kyoto University Katsura, Kyoto 615-8510, Japan Email: akagi@fps.polym.kyoto-u.ac.jp It is well known that polyacetylene is a one-dimensional conjugated macromolecule and a good representative for conducting polymers.1Pristine polyacetylene is a ty...

NIPAM based Polymers

Gangadhar Panambur, Ilya Koltover and Scott Batcheller MilliporeSigma, 6000 N. Teutonia Milwaukee, WI 53209 Stimuli-responsive Polymers Stimuli-responsive polymers, also known as “smart” polymers or “environmentally sensitive” polymers, undergo rapid changes in their microstructure from a hydrophili...

Customer-Driven Innovation: Collaborate with us to drive your assay development

We understand that it can be challenging to bring an assay to market and that your resources can be stretched thin while optimizing reagents, samples and systems. Our Customer-Driven Innovation (CDI) program aims to help you by putting our R&D resources into your hands. From creating a better raw ma...

Antibody-Drug Conjugation [VIDEO]

Antibody-Drug Conjugation Video SAFC offers a comprehensive range of ADC services needed for development, manufacturing, and testing of bulk drug substance and drug product. Our latest offering to simplify your path to the patient is the opening of our state-of-the-art Commercial ADC manufacturing s...

Free Radical Initiators

Photoinitiators | Thermal Initiators | Stabilizers Initiator/Stabilizer FAQ Dr. S.S. Newaz Polyorganix Inc., Houston, TX Q. How does one choose the appropriate initiator? In a free radical addition polymerization, the choice of polymerization initiator depends mainly on two factors: a) its solubilit...

Delivery of Nucleic Acids Using Polymers

Olivia Merkel Wayne State University, Detroit, Michigan Email: olivia.merkel@wayne.edu The medical application of molecular nanotechnology, referred to as “nanomedicine,” is believed to lead to progress in human therapeutics in terms of improving health at the molecular scale.1 This has great potent...

ADCs & Bioconjugation

REQUEST INFORMATION With more than 35 years of experience, we are a leading expert in the conjugation of highly active molecules to monoclonal antibodies for the development and manufacture of antibody-drug conjugates (ADCs). Targeted Delivery Through Conjugation Antibody-drug conjugation technology...

Aggregation-induced Emission Luminogens for Non-doped Organic Light-emitting Diodes

Han Nie,1 Zujin Zhao1a and Ben Zhong Tang1,2,3b 1State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, China 2Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China 3Hong Kon...

Atto Dyes for Superior Fluorescent Imaging

• Alternatives to common Fluorophores • Reactive Atto Dyes • Atto Dye Conjugates Activated fluorescent dyes are routinely used to tag proteins, nucleic acids, and other biomolecules for use in life science applications including fluorescence microscopy, flow cytometry, fluorescence in situ hybridiza...

Polytriarylamine Semiconductors

• Flexink Limited - www.flexink.co.uk Southampton, UK E-mail: sales@flexink.co.uk Organic electronics is an emerging scientific field of potentially huge technological and commercial relevance1, and is an increasingly ubiquitous research activity globally. One important area is the development of or...

Optoelectronic Devices Based on Diketopyrrolopyrrole (DPP)-containing Conjugated Small Molecules

Jianhua Liu and Thuc-Quyen Nguyen* Center for Polymers and Organic Solids Department of Chemistry & Biochemistry University of California, Santa Barbara, California 93106, United States *Email: quyen@chem.ucsb.edu Optoelectronic devices such as light-emitting diodes (LEDs), solar cells, and light-em...

ADC Mimic Enables LC-MS Method Development

A non-toxic Cys-conjugated ADC-mimic characterized by top-down, middle-out, and bottom-up LC-MS methods. ADCs conjugated at Cys residues of inter-chain disulfide bonds give mAbs bearing 0-4 pairs of drug-linkers. Characterizing this distribution is paramount to understanding ADC efficacy and process...

Initiator/Stabilizer FAQs

• • Download PDF • Dr. S. S. Newaz Polyorganix Inc. Houston, TX Q. How does one choose an appropriate initiator? In a free-radical addition polymerization, the choice of polymerization initiator depends mainly on two factors: a) its solubility and b) its decomposition temperature. If the polymerizat...

Bile Acids Kit for LC-MS

A Rapid and Reliable Kit for Bile Acids Research Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes. BA analysis is an important area of study in various settings including clinical ...

Next-Gen ADCs: Collaborating to Improve Supply Chains for Development and Technology Transfer with Novel Technology Platforms

Related Links • Safe Manufacture of Antibody Drug Conjugates • Antibody-Drug Conjugates (ADCs) • Baxter BioPharma Solutions • • Download PDF • Dr. Cynthia Wooge Global Segment Marketing Manager, SAFC Dr. Jyothi Swamy QC Supervisor, SAFC A look into today’s ADC landscape and how collaboration aims to...

Inverse Electron Demand Diels–Alder Reactions of 1,2,4,5-Tetrazines and 1,2,3-Triazines

The inverse electron demand Diels-Alder reactions of electron-deficient heterocycles are significant cycloaddition reactions for the total synthesis of natural products containing highly substituted and functionalized heteroaromatic ring systems. In collaboration with Professor Dale Boger, we are pl...

Duolink® PLA Probemaker Guide for Multicolor Detection

This guide describes the use of the Duolink® PLA Multicolor Probemaker kits for the conjugation of a unique pair of PLA oligonucleotides (Red Oligos A and B, Green Oligos C and D, Orange Oligos F and G, or FarRed Oligos H and I) to a pair of primary antibodies for use in Multicolor Duolink® PLA expe...

Chemistry at Surfaces with Self-Assembled Monolayers and SAMDI-ToF Mass Spectrometry

Prof. Milan Mrksich Department of Chemistry The University of Chicago Chicago, IL mmrksich@uchicago.edu Modern synthetic chemistry permits the construction of elaborate molecular structures and has been vital to the development of pharmaceuticals, catalysts, and functional polymers. Chemists no long...

Applications of Quantum Dots in Bioimaging and Bioassays

1 Program in Immunology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109, USA 2 Department of Bioengineering, University of Washington, 3720 15th Ave NE, WA 98195, USA * E-mail: xgao@uw.edu Article Sections • Introduction • QD Developments • QD Bioapplications • Perspe...

Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents

David Brown,1 Keith Brunt,2 Nils Rehmann3 1CTO Mycodev Group, Fredericton, NB E3B 6B3 Canada 2Dalhousie School of Medicine New Brunswick, Saint John, NB E2K 5E2, Canada 3NiRem Consulting, 8 Fish Hatchery Lane, French Village, NB E3E 2H5, Canada Email: Dave@mycodevgroup.com,1 Nils@nirem.ca3 Chitosan ...

Gumweed (Grindelia squarrosa) | Plant Profiler

Synonyms / Common Names / Related Terms Asteraceae (family), August flower, California gumplant, grindelia, Grindelia camporum, Grindelia robusta, Grindeliae herba, Grindelie, gum plant, gumplant, gum weed, hardy grindelia, rosin weed, scaly grindelia, tar weed, tarweed. Mechanism of Action Pharmaco...