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133 matches found for bacterial_conjugations

Protein and Peptide Polymer Conjugates

1Department of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K. 2Warwick Medical School, The University of Warwick, Coventry CV4 7AL, U.K. 3Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, VIC 3052, Australia *Email: s.perrier@warwick.ac.uk The modification of biomacro...

NIPAM based Polymers

Gangadhar Panambur, Ilya Koltover and Scott Batcheller MilliporeSigma, 6000 N. Teutonia Milwaukee, WI 53209 Stimuli-responsive Polymers Stimuli-responsive polymers, also known as “smart” polymers or “environmentally sensitive” polymers, undergo rapid changes in their microstructure from a hydrophili...

Next-Gen ADCs: Collaborating to Improve Supply Chains for Development and Technology Transfer with Novel Technology Platforms

Related Links • Safe Manufacture of Antibody Drug Conjugates • Antibody-Drug Conjugates (ADCs) • Baxter BioPharma Solutions • • Download PDF • Dr. Cynthia Wooge Global Segment Marketing Manager, SAFC Dr. Jyothi Swamy QC Supervisor, SAFC A look into today’s ADC landscape and how collaboration aims to...

Customer-Driven Innovation: Collaborate with us to drive your assay development

We understand that it can be challenging to bring an assay to market and that your resources can be stretched thin while optimizing reagents, samples and systems. Our Customer-Driven Innovation (CDI) program aims to help you by putting our R&D resources into your hands. From creating a better raw ma...

Functionalization of Fluorescent Nanodiamonds for Bioimaging

Related Products • Fluorescent Nanodiamonds • PEGs & PEOs • Nanomaterials Related Content • Nanomaterial Bioconjugation Techniques • Monodispersed Nanodiamonds & their Applications • Nanomaterials What are Fluorescent Nanodiamonds? Fluorescent nanodiamonds (FNDs) exhibit distinct properties such as ...

"Click" Chemistry in (Bio)Materials Science

• • Download PDF • 1Organic Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, The Netherlands 2Encapson B.V, The Netherlands j.vanhest@science.ru.nl Combining biomolecules and synthetic polymers into a new class of versatile biohybrid materials with many (future) fields ...

Atto Dyes for Superior Fluorescent Imaging

• Alternatives to common Fluorophores • Reactive Atto Dyes • Atto Dye Conjugates Activated fluorescent dyes are routinely used to tag proteins, nucleic acids, and other biomolecules for use in life science applications including fluorescence microscopy, flow cytometry, fluorescence in situ hybridiza...

Functional RAFT Polymers for Biomedical Applications

M. Shahinur Rahman, Sebastian Grajales MilliporeSigma, Milwaukee, WI Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles. The RAFT technique allows unprecedented latitude in the synthesis of wate...

MALDI-TOF Characterization of Functionalized Polymers

With an increased demand for high performance and specialized polymeric materials, tools for selective end group functionalization and modification have been a focus of synthetic development. Due to their tunable physical and chemical properties, polymers are an essential component for a variety of ...

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

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Increasing the Senstivity of Lateral Flow Diagnostic Assays with Ultra-Bright Gold Nanoshell Reporters

nanoComposix, San Diego, CA 92111, USA E-mail: steve.oldenburg@nanocomposix.com Article Sections • Introduction • Lateral Flow Assay Formats • Nanoparticles as Reporters in Lateral Flow • Covalent Linkage Chemistry for High Stability Reporters • Interpreting Results from Lateral Flow Tests • Conclus...

Enzyme Explorer Drug Metabolism Tech Review

Multi-Drug Resistance in Cancer - Role of ABC Transporter Proteins Balázs Sarkadi1, Gergely Szakás1,2 and András Váradi3 1. National Medical Center, Institute of Hematology and Immunology, Budapest, Hungary 2. National Cancer Institute, NIH, Bethesda, MD, USA 3. Institute of Enzymology, Hungarian Ac...

NLO Materials

Introduction Crystal Grade Materials Plastic Optical Fibers References Organic NLO Materials The field of organic nonlinear optics has come a long way since the its triggering development in 1970. In that year, Davydov et al. reported a strong second harmonic generation (SHG) in organic molecules ha...

Duolink® PLA Troubleshooting Guide

Tips & Tricks • Upfront Considerations • Common Experimental Parameters • Sample Storage and Analysis Troubleshooting • Too High of a Background Signal • Low or Lack of Signal • Poor Imaging & Analysis Frequently Asked Questions • General Questions • Protocol and Analysis • Specific Requirements • D...

Organic Field Effect Transistors Based on DNTT and Related Organic Semiconductors

Professor Kazuo Takimiya Emergent Molecular Function Research Group, RIKEN Center for Emergent Matter Science (CEMS), Wako, Saitama 351-0198, Japan FAX: +81-48-462-1473 Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University, Higashi-Hiroshima 739-8527, Japan Introducti...

Authenticated Colorectal Cancer Cell Lines for Cancer Research

Related Links • Cell Culture • ECACC Cell Lines • Protocols for ECACC Cell Lines • Browse Colorectal Cancer Cell Lines Related Articles • Exploring Colon Cancer with Prestige Antibodies® • MSI Testing and IHC • Colorectal Cancer and Immunohistochemistry • Breast Cancer Cell Lines • Liver Cancer Cell...

Organic Bioelectronic Materials and Devices for Bridging Biology and Traditional Electronics

1 Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA 2 Simpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL 60611, USA 3 Department of Chemistry, Imperial College London, London SW7 2AZ, UK 4 Department of Physics and Center for Pl...

Applications of Conducting Polymer Devices in Life Sciences

Leslie H. Jimison1, Dion Khodagholy1, Thomas Doublet1,2, Christophe Bernard2, George G. Malliaras1, and Róisín M. Owens1 1Department of Bioelectronics, Ecole Nationale Supérieure des Mines CMP-EMSE, MOC, 880 route de Mimet, 13541 Gardanne, France (www.bel.emse.fr) 2Institut de Neurosciences des Syst...

Degradex® Microspheres and Nanoparticles for Drug Delivery Research and Formulation Development

Related Articles • Dendrons and Hyperbranched Polymers: Multifunctional Tools for Materials Chemistry Microspheres and nanoparticles of biodegradable polymers such as PLGA, polylactic acid, and polycaprolactone have been widely used in drug delivery. Active pharmaceutical ingredients (APIs), whether...

ZooMAb® Antibodies Frequently Asked Questions

Related Links • View all ZooMAb® Antibody Products • ZooMAb® Antibodies • ZooMAb® Antibodies Technical Article • Antibody Explorer • Highly Cited Antibodies • Antibody Guarantee 1. Why are these called ZooMAb® antibodies? 2. How do I know what species my ZooMAb® antibody is? 3. How many species do y...

OEM and Contract Manufacturing Services

Key Technologies • Molecular Amplification • Oligos, probes, amidites • DNA/RNA enzymes • Molecular-grade buffers, formulations • Nucleic acid purification • Conjugation • Large molecules to beads/resins • Linkage chemistry • Detection reagents • Detection Chemistry • Chemiluminescence • Colormetric...

ADCs & Bioconjugation

REQUEST INFORMATION With more than 35 years of experience, we are a leading expert in the conjugation of highly active molecules to monoclonal antibodies for the development and manufacture of antibody-drug conjugates (ADCs). Targeted Delivery Through Conjugation Antibody-drug conjugation technology...

Solubility Enhancement of Poorly Water Soluble Molecules using Dendrimers

CTO; Dendritic Nanotechnologies, Inc. Environmental concerns are driving the replacement of volatile organic solvents by water and aqueous mixtures. This change often creates challenges because many organic molecules show low water solubility. In addition, in some applications it is necessary to mix...

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of ethylene oxide to produce a broad range of molecular weights and molecular weight distributions (polydi...

Create Your Own PLA® Probes

Duolink® kits use in situ PLA®, a proximity ligation assay technology, to accurately and objectively quantify individual proteins, and their interactions and modifications in unmodified cells and tissue. Direct detection and localization of protein interactions are achieved with unparalleled specifi...

Biologic APIs and Conjugation Experts – SAFC - St. Louis

Contact SAFC • Contract Manufacturing Inquiries SAFC’s St. Louis, Missouri (USA) campus is a key center of manufacturing excellence in cGMP biologics, with over 25 years experience in plant- and animal-based therapeutic protein extraction and purification, bio-conjugation, excipients and adjuvants m...

Drug Delivery FAQs

Related Links • Polymeric Drug Delivery Techniques • Webinar: High-capacity drug-delivery systems for cancer therapy based on poly(2-oxazoline)s Related Products • Hydrophilic Polymers • Biodegradable Polymers • What are the differences between encapsulation efficiency, loading capacity, and yield? ...

Chemistry at Surfaces with Self-Assembled Monolayers and SAMDI-ToF Mass Spectrometry

Prof. Milan Mrksich Department of Chemistry The University of Chicago Chicago, IL mmrksich@uchicago.edu Modern synthetic chemistry permits the construction of elaborate molecular structures and has been vital to the development of pharmaceuticals, catalysts, and functional polymers. Chemists no long...

How to Optimize Duolink® PLA for Flow Cytometry Detection

Adaptation of Duolink® in situ proximity ligation assay (PLA) into flow cytometry workflows allows quantitative detection of protein-protein interactions, protein post-translational modifications, and protein expression with greater statistical power. However, to successfully execute Duolink® PLA fo...

Functionalized Polyethylene Glycol (PEG) Reagents

Related Links • PEG Selection Guide The chemical modification of biologically active compounds, such as peptides, proteins, antibody fragments, aptamers, enzymes, and small molecules with polyethylene glycol (referred to as “PEGylation”), is an effective method to tailor molecular properties to part...