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133 matches found for bacterial_conjugations

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Jiayu Leong,1 Liam Grover,2 Hyunjoon Kong1* 1Department of Chemical and Biomolecular Engineering University of Illinois, Urbana-Champaign, IL 61801 USA 2University of Birmingham, UK *Email: hjkong06@illinois.edu Collagen molecules play a critical role in tissue architecture and strength, and in cell...

High Potent APIs

REQUEST INFORMATION High potent active pharmaceutical ingredients (HPAPI) are effective at much smaller dosage levels than traditional APIs, but their potent characteristics present specific handling challenges. As a leader in this area, we offer: • 25 years of experience in HPAPI development and ma...

Autophagy and Mitophagy in Tumor Cell Survival and Death

Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle them. In mammalian cells, autophagy occurs constitutively at basal rates and its primary function is to...

FITC-labelled polysaccharides

FITC-Dextran FITC-DEAE-dextran (FDD) FITC-carboxymethyl-dextran (FCM-Dextran) FITC-polysucrose (FITC-Ficoll®) FITC-DEAE-polysucrose FITC-CM-polysucrose (FITC-CM-Ficoll®) FITC-inulin Fluorescein hyaluronic acid (FHA-Se) TRITC-labelled polysaccharides TRITC-polysucrose (TRITC-Ficoll®) Tetramethyl-rhod...

Procedure for Conjugation of Alkaline Phosphatase to Antibodies and Other Proteins

Procedure for Conjugation of Alkaline Phosphatase to Antibodies and Other Proteins At least five different methods for conjugation of alkaline phosphatases to proteins have been described.1 The most popular method is the one-step glutaraldehyde coupling method.2 Procedure: 1. Combine 10 mg of antibo...

Extended Lifetime Ethanol Metabolites and Method Development for Ethyl Sulfate and Ethyl Glucuronide Separation

In this study methods are presented for ethanol metabolites ethyl glucuronide (EtG) and ethyl sulfate (EtS) Alcohol abuse remains an epidemic causing widespread health, legal, and economic impacts. Extreme abuse has escalated in volume and cases of alcohol abuse are consistently increasing in younge...

Secondary Antibodies, Conjugates and Kits

Related Links • Antibody Explorer • How to Choose a Secondary Antibody Secondary antibodies are polyclonal or monoclonal antibodies that bind to primary antibodies or antibody fragments, such as the Fc or Fab regions. They are typically labeled with probes that make them useful for detection, purifi...

Silica-coated Gold Nanoparticles: Surface Chemistry, Properties, Benefits and Applications

In the past few decades, research and commercial use of gold nanoparticles has rapidly expanded into fields extending from biomedical engineering1 to photovoltaics.2 Most applications take advantage of the excellent optical properties of gold nanoparticles, which can be fine-tuned by varying their s...

Molybdenum Disulfide: Understanding Hydrogen Evolution Catalysis

Linyou Cao Department of Materials Science and Engineering Department of Physics North Carolina State University, Raleigh, NC, USA Email: lcao2@ncsu.edu The production of hydrogen by catalytic water splitting is important for a wide range of industries including renewable energy petroleum refining a...

Development of Small Molecule Donors for Solution-Processed Organic Solar Cells

Abby-Jo Payne and Gregory C. Welch Dalhousie University, Department of Chemistry 6274 Coburg Road, Halifax, Nova Scotia, Canada B3H 4R2 Email: gregory.welch@dal.ca Solution-processed organic photovoltaic devices (OPVs) have emerged as a promising clean energy generating technology due to their ease ...

Safe Manufacture of Antibody Drug Conjugates

Although antibody-drug conjugates show promise in the development of effective cancer therapies, there are still a variety of challenges involved in enabling the safe manufacture of these hazardous drugs. Antibody-drug conjugates (ADCs) – anti-cancer drugs which combine the specificity of a monoclon...

Enzyme Explorer Lectin Index

We have the largest selection of lectins and lectin conjugates available, with over 100 products from over 35 sources. Backed by quality and service you’ve come to expect, we offer lectins for all your life science applications, including: • Histochemical Studies • Lymphocyte Subpopulations Studies ...

Partial PROTACs for Targeted Protein Degradation

An emerging strategy in drug discovery to access difficult-to-treat diseases is targeted protein degradation. While traditional small-molecule or antibody drugs may only allow access to ~20% of the proteome, degradation techniques may open the door to the other 80%.1 The molecules used in these appr...