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EPH receptor A2
Species Human (1969) , Species Mouse (13836) , Species Rat (366492) , Species domestic guinea pig (100712747) , Species naked mole-rat (101714513) , Species sheep (101110575) , Species Domestic Rabbit (100343518) , Species Zebrafish (30689) , Species chicken (771550) , Species cow (512798) , Species Horse (100053644) , Species domestic cat (101085481) , Species dog (487421)
Summary: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]