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Search term:"3.4.11.2"

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3 matches found for 3.4.11.2

Leucine Aminopeptidase, microsomal from porcine kidney

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membrane-associated ring finger (C3HC4) 11
Synonyms MARCH-XI
Species Human (441061) , Species Mouse (211147) , Species Rat (499558) , Species Zebrafish (798174) , Species cow (781742) , Species domestic cat (101089674) , Species dog (479384) , Species chicken (420914) , Species sheep (101102675) , Species naked mole-rat (101705369) , Species domestic guinea pig (100720329)
Summary: MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]