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Search term:"95-95-4"

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3 matches found for 95-95-4

2,4,5-Trichlorophenol

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  • |  Match Criteria: CAS Number, Related Cas Number

2,4,5-Trichlorophenol 95%
    • Linear Formula: Cl3C6H2OH

    • Molecular Weight: 197.45

    • CAS Number: 95-95-4

4-aminobutyrate aminotransferase
Synonyms GABA-AT, GABAT, NPD009
Species Human (18) , Species Mouse (268860) , Species Rat (81632) , Species Zebrafish (378968) , Species cow (280969) , Species Horse (100051470) , Species domestic cat (101089064) , Species dog (479856) , Species chicken (416642) , Species naked mole-rat (101712584) , Species domestic guinea pig (100725419) , Species Goat (100861058) , Species sheep (101105462)
Summary: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]