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1 match found for Akt1/2 kinase inhibitor

Akt1/2 kinase inhibitor

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Akt1/2 kinase inhibitor ≥98% (HPLC)
  • Synonym: 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one trifluoroacetate salt hydrate, Akt Inhibitor VIII trifluoroacetate salt hydrate, Akti-1/2 trifluoroacetate salt hydrate

    • Empirical Formula (Hill Notation): C34H29N7O · xC2HF3O2 · yH2O

    • Molecular Weight: 551.64 (anhydrous free base basis)

calcium/calmodulin-dependent protein kinase II inhibitor 2
Species Human (94032) , Species Mouse (73047) , Species Rat (59314) , Species Zebrafish (436915) , Species dog (607194) , Species cow (614606) , Species naked mole-rat (101714073)
Summary: This gene encodes a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors. [provided by RefSeq, Jul 2008]