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182 matches found for cell_proliferation

Psyllium (Plantago ovata) | Plant Profiler

Synonyms / Common Names / Related Terms Arabinose, Bran Buds® cereal, bulk laxative, Effersyllium®, fiber, Fiberall®, Fiber-loop cereal, flea seed, fleawort, Fybogel®, Heartwise® cereal, hemicellulose, Hydrocil®, Indian plantago seed, isabgol, I-so-gel®, ispaggol, ispaghula, ispaghula husk, ispaghul...

Autophagy and Mitophagy in Tumor Cell Survival and Death

Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle them. In mammalian cells, autophagy occurs constitutively at basal rates and its primary function is to...

Propolis (Propolis) | Plant Profiler

Synonyms / Common Names / Related Terms Apis mellifera L., bee glue, bee propolis, bee putty, Bienenharz (German), Brazilian green propolis, Brazilian propolis, Bulgarian propolis, caffeic acid phenethyl ester, CAPE, cera alba, chizukit, cinnamic acid, flavonoids, galangin, Greek propolis, hive dros...

Growth Factors and Cytokines Review

Jennifer Fries Technical Marketing Specialist, Cell Culture The importance of cytokines and growth factors in cell culture has been demonstrated time and time again since the inception of cell culture. Beginning with the first successful efforts of growing cells in culture, there have been so called...

EGF/EGFR signaling pathway

Background Epidermal Growth Factor Receptors (EGFR) and ligands Receptor activation EGFR Signaling Ras/Raf signaling cascade Phosphatidylinositol 3-kinase/Akt signaling cascade Signal transducers and activators of transcription (STAT) pathway Phospholipase Cγ signaling Nck/PAK signaling cascade Cbl ...

MAPKs

The mitogen-activated protein kinase (MAPK) family consists of both stress activated (SAPK) and mitogen-activated (MAPK) protein kinases. They form a network of signal transduction cascades that mediate cellular responses to a diverse range of stimuli, including growth factors, chemical or osmotic s...

The Tumor Microenvironment

Several recent reviews underscore the contribution of the microenvironment to tumor development.12,15-18 While the normal cellular microenvironment can inhibit malignant cell growth, the modifications that occur in the tumor microenvironment synergistically support cell proliferation. Tumors shape t...

Nanofiber Scaffold Technology

Cell culture has been traditionally conducted on flat plastic substrates to study cell and tissue biology. These two-dimensional (2D) substrates are inadequate in fully capturing the complexities and intricacies presented to the cells in vivo. The ability to transition from these flat surfaces to te...

Tumor-Spheroid-Formation-Assay

Cancer research is one of today’s major research fields producing thousands of publications every year. Traditional therapeutic approaches aim to eliminate as much of the tumor mass as possible by means of surgery, irradiation, chemotherapy and biologics. However, evidence suggests that these techni...

upregulator of cell proliferation
Synonyms URG4
Species Human (55665) , Species Mouse (72046) , Species Rat (305493) , Species domestic cat (101097628) , Species Horse (100064842) , Species dog (610578) , Species cow (504226) , Species sheep (101122140) , Species domestic guinea pig (100717908) , Species naked mole-rat (101696326)
Summary: URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]

LONG®R3IGF-I: An Insulin Alternative Exclusively for Cell Culture Applications

• • Download PDF • LONG®R3IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. LONG®R3IGF-I is more biologically potent in vitro than either insulin or native IGF-I and has been shown to sig...

Building Blocks for Introducing Post-translational Modified Amino Acids

The Novabiochem® product line has always been at the forefront of the development for methods for the synthesis of peptides containing PTMs, being the first company to provide effective building blocks for synthesis of phosphorylated peptides, and sulfotyrosine and methylated arginine containing pep...

Met

The Met family of receptor tyrosine kinases (RTKs) contains two members in mammals, referred to as Met and Ron. Met is the receptor for hepatocyte growth factor/scatter factor (HGF/SF), while Ron is the receptor for macrophage stimulating protein (MSP). In the adult, Met is predominantly expressed i...

Cranberry (Vaccinium macrocarpon) | Plant Profiler

Synonyms / Common Names / Related Terms Alpha-linolenic acid, American cranberry, anthocyanins, Arandano Americano, Arandano trepador, ascorbic acid, Azo-cranberry®, bear berry, benzoic acid, black cranberry, bog cranberry, catechins, cinnamic acids, citric acid, coumaroyl iridoid glycosides, ellagi...

Growth Factors in Stem Cell Biology

Related Links • Growth factors • 3D-cell culture • Organoids • Pluripotent Stem Cell Culture • Stem cell basics Related Products • Cell Culture Media and Reagents • Growth Factors • Stem Cell Antibodies • CRISPR Genome Editing • 3D Cell Culture • ECACC cell lines • 3DKUBE • 3D Hydrogels Growth facto...

A Novel 3D Perfusion Bioreactor

Qing Liu, Ph.D., is an expert in biomaterials, tissue engineering, and in vitro tissue model for drug screening. Carlos E. Caicedo-Carvajal, Ph.D., has worked in several areas of Biomedical Engineering, including 3D tissue organization and engineering of 3D in vitro models for tissue regeneration an...

Vascular Pericytes

Figure 1. Vascular pericyte overview. Pericytes surround blood vessel capillaries and endothelial cells, neurons and astrocytes within the blood-brain-barrier (BBB) neurovascular unit. Pericytes, also known as mural cells, are multipotent perivascular cells that play an important role in the develop...

Horseradish (Armoracia rusticana) | Plant Profiler

Synonyms / Common Names / Related Links Allyl isothiocyanate, allylisothiocyanate, Armoracia lapathifolia Gilib., Armoracia rusticana, Armoracia rusticana Gaertner, Armoracia sativa Heller, Amoraciae Rusticanae Radix, Bohemian horseradish, Brassicaceae (family), Cochlearia armoracia, Cochlearia rust...

Nephrotoxicity Assays

Nephrotoxicity or kidney toxicity occurs when a substance has an adverse or poisonous effect on the kidneys. Kidney toxicity is a continuing concern during drug development. In particular, renal proximal tubular epithelial cells (RPTECs) are frequently affected due to their roles in filtrate resorpt...

HyStem™ Glossary of Terms

A | B | C | D | E | F | G | H | I | L | M | N | O | P | R | S | T | U A Acinus (plural: acini) - The word comes from the latin word “grape”. It refers to the sac-like termination of a secretary exocrine gland. In vitro, mammary epithelial cells cultured in a laminin-rich matrix form acinus-like sphe...

Receptors and Inhibitors: Scratching the Surface of Bioactive Small Molecules for EGFR Research

Biowire Spring 2011 — Cell Lines — Models of Disease Epidermal growth factor receptor (EGFR) is a principle member of the receptor tyrosine kinases (RTKs) family of cell-surface growthfactor receptors. Its members include EGFR (ErbB1 or HER1; Product Nos. E3641 and E2645), HER2/neu (ErbB2), HER3 (Er...

Baikal skullcap (Scutellaria baicalensis) | Plant Profiler

Synonyms / Common Names / Related Terms Apigenin, apigenin-7-O-beta-glucoside, apigenin-7-O-neohesperidoside, baicalin, ban-ji-ryun (Korean), banjiryun (Korean), ban-zhi-lian (Chinese), barbatin A, barbatin B, barbatin C, benzyaldehyde, berberine, BZL101, carthamidin, ethyl-7-O-apigenin-glucuronate,...

Bilberry (Vaccinium myrtillus) | Plant Profiler

Synonyms / Common Names / Related Terms Airelle, anthocyanins, Bickbeere (German), bilberry leaf, black whortle, Blaubeere (Dutch), blaubessen, bleaberry, blueberry, blueberry leaf, bogberry, bog bilberry, burren myrtle, cranberry, dwarf bilberry, dyeberry, Ericaceae (family), European blueberry, He...

3D-Mammosphere-Culture-Media

Mammospheres, or mammary epithelial stem cell aggregates, derived from primary breast tumors or cell lines are thought to develop from rare cancer stem cell (CSC) subpopulations within the tumor. The progression and recurrence of breast cancer, the leading cause of cancer death in women, has been li...

Hematopoietic Cytokines

• • Download PDF • Related Links • Growth factors • Pluripotent Stem Cell Culture • Growth factors and cytokines • Interleukins • Antibodies to cytokines and growth factors • Hematopoietic Stem Cell Culture Related products • Cell Culture Media and Reagents • Growth Factors • Hematopoietic cytokines...

Micro- and Nanofabricated Biomaterials for the Study of Cells and Microtissues

Phin Peng Lee, Karen E. Samy, Miquella G. Chavez, Alec Cerchiari, Tejal A. Desai* Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94158 USA *Email: tejal.desai@ucsf.edu Biomaterials science involves the design and fabrication of smart ...

Choosing Lipophilic Dye Kit for Cell Tracking

• • Download PDF • Supplemental Information Katharine A. Muirhead, Joseph D. Tario, Jr., Paul K. Wallace Table S1. Non-Perturbing Membrane-Dye Labeling Conditions for Selected Cell Types1 Cell Type Final Cell Concentration Final Dye Concentration hPBMC* (large cell number) 1 x 107 cells/mL 3 x 107 c...

Cultrex® 3-D Spheroid Colorimetric Proliferation/Viability Assay Protocol

Reagent kit for investigating spheroid cell proliferation and/or viability Catalog Number 3511-096-K Current in vitro tumor models lack either a physiological context and/or reproducible format for evaluating tumor cells in vitro. At present, the most popular method for compound screening and pathwa...

Glycan Labeling

Glycobiology Analysis Manual Table of Contents GlycoProfile™ Products for Metabolic Glycan Labeling FLAG® Antibodies for Detection of FLAG-labeled Glycans GlycoProfile™ Labeling Kits Fluorophores Chromophores Additional Reagents for Reductive Amination Structural modifications of proteins are essent...

Baseclick EdU Cell Proliferation Detection Kits: Improve Data Quality and Save Time

Experimental studies measuring cell proliferation have had implications in cancer biology, immunology, cell biology, and developmental biology. Various methods for monitoring cell proliferation have been developed. Counting cells using a hemocytometer is one of the simplest methods used to monitor c...

Potassium Channels

Potassium channels are essential in both excitable and non-excitable cells for the control of membrane potential, regulation of cell volume, and the secretion of salt, neurotransmitters and hormones. They are integral membrane proteins that allow the selective, diffusional passage of potassium ions ...