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343 matches found for diagnostic

Protease Inhibitor Cocktails References

Our portfolio of protease inhibitor cocktails are frequently cited in peer-reviewed scientific literature, suggesting their superior quality and excellent track record. This page lists a sampling of those research papers. Other citations are available under the specific product pages for each of our...

Lung Cancer & IHC Webinar

Webinar Title: Lung Cancer & IHC Duration: 60 minutes Each year, over 222,000 people are diagnosed with lung cancer, and over 150,000 succumb to the illness, making it the deadliest cancer in the United States. With advancements in treatment options, the importance of accurate diagnosis and detectio...

Oligonucleotide Label Licenses

Sold under license from Roche Diagnostics GmbH. For research use only. No license under these patents to use the PCR Process is conveyed expressly or by implication to the purchaser by the purchase of this product. Further information on purchasing licenses to practice the PCR process may be obtaine...

LC-MS Analysis of Vitamin D Metabolites

Vitamin D deficiency has become a topic of interest in recent publications.1-3 Vitamin D, along with calcium, promotes proper bone growth in children and aids in the prevention of osteoporosis in older adults. Vitamin D is present in two forms, Vitamin D3 and Vitamin D2. D3 is produced after ultravi...

DNAstable® Plus Handbook

Protocols for Sample Protection, Sample Recovery and Downstream Applications • Introduction • Principles and Procedures • Storage • Applications • Important Notes • Protocol: Sample preparation • Protocol: Sample drying and storage • Protocol: Drydown Sample recovery • Protocol: Downstream applicati...

CampBridge ELISA Kit Protocol

Product Number. ABK0003 Complete kit for the systematic 3-D conformational comparability analysis of Campath biosimilar molecule to Alemtuzumab (Campath trade name). Read the entire protocol before performing the assay. This kit is intended for research use only and not for use in diagnostic procedu...

Selective Media for Bifidobacteria

Product Manager Microbiology ivo.siegrist@sial.com Sigma-Aldrich® supplies media for the selective isolation, identifi cation and enumeration of bifidobacteria like Bifidobacterium longum, infantis and brevi which are used for quality control in the manufacture of dairy products. Bifi dobacteria are...

Lymphomas and Leukemias Webinar

Leukemia and lymphoma are hematologic neoplasms that affect members of all age groups. Each year, over 140,000 people in the US are diagnosed with a hematologic malignancy of some kind. With constant advancement of treatment options, the importance of accurate diagnosis and detection of lymphomas an...

Kyoto (iPS-AJ) Label License

1. SA Licensed Pluripotent Products (i) End User shall not use SA Pluripotent Products and its derivatives for uses other than for End User’s internal use in the Field and in the Territory. (ii) Notwithstanding above, if End User wishes to use SA Pluripotent Products and its derivatives in the Field...

immunoglobulin-like domain containing receptor 1
Synonyms DFNB42, ILDR1alpha, ILDR1alpha', ILDR1beta
Species Human (286676) , Species Mouse (106347) , Species Rat (303914) , Species chicken (418358) , Species domestic cat (101090132) , Species cow (538495) , Species dog (608570) , Species sheep (101112275) , Species domestic guinea pig (100724567) , Species naked mole-rat (101723491)
Summary: This gene encodes a protein that contains an immunoglobulin-like domain. The encoded protein may function as a multimeric receptor at the cell surface. The expression of this gene may be a diagnostic marker for cancer progression. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Transplex® RNA Amplification Kit: Whole Transcriptome Amplification of Highly-Degraded RNA from FFPE Tissues.

Ken Heuermann and Brian Ward Research and Development, Biotechnology Division, Sigma-Aldrich The TransPlex Complete Whole Transcriptome Amplification (WTA2 ) Kit effectively amplifies intact and highly degraded RNA. To benchmark maintenance of representative RNA levels during amplification, differen...

DIG Technical Tips

High specificity and sensitivity are the reason, researchers worldwide choose the DIG System to detect nucleic acids using filter and in situ hybridization. Compared to radioactivity less target material is needed for robust results because sensitivity is high. The DIG labeling moiety is the steroid...

DenoBridge ELISA Kit Protocol

Product Number. ABK0013 Complete kit for the systematic 3-D conformational comparability analysis of Prolia biosimilar molecule to Prolia (Denosumab trade name). Read the entire protocol before performing the assay. This kit is intended for research use only and not for use in diagnostic procedures....

Pluripotent and Multipotent Stem Cells

Related Products • Stem Cell Culture • Stem Cell Protocols • Pluripotent Stem Cell Culture • Neural Stem Cell Culture • Mesenchymal Stem Cell Culture • Hematopoietic Stem Cell Culture • Cell Culture Media and Reagents • Growth Factors • ECM Protein • Stem Cell Antibodies • CRISPR Genome Editing • 3D...

Buffer Solutions

Product development in IVD relies on the quality and performance of raw materials that constitute the basic components of any reagent/kit. Buffers constitute a major critical reagent and help stabilize the reaction for analyte detection. Buffer solutions from Sigma-Aldrich are characterized by the a...

GenomePlex® WGA Reamplification Kit

The GenomePlex® WGA Reamplification Kit (WGA3) allows subsequent reamplifications of the initial WGA product. The successive reamplification provides DNA with little genetic bias when compared to the original genome. The Reamplification kit contains the WGA DNA Polymerase and the 10X Master Amplific...

Salmonella Contamination and Testing

Related Information • Food and Beverage Home • Food Microbiological Control • ISO 6579 – Salmonella Detection • ISO 11133 – Food Microbiological Testing • GranuCult™ Culture Media Request more information Request more information Foodborne illness affects public health and development worldwide. Sal...

Proligo® Phosphoramidites and Reagents

The Proligo® reagents portfolio offers a full range of phosphoramidites, solid supports and liquid reagents for oligonucleotide synthesis that include the following features: • High quality standard and specialized products for the complete workflow • Flexible and customizable production and packagi...

Biomatrica Selection Guide

Biomatrica products enable researchers in academia, pharmaceutical drug development, and molecular diagnostics to stabilize ship and store biological samples for long periods of time with complete and rapid sample recovery, all at very affordable costs. Its SampleMatrix® proprietary core technology ...

Analyzing real-time PCR data by the comparative CT method

Nature Protocols Volume 3 Issue 6, 05 June 2008, Pages 1101 - 1108 doi: 10.1038/nprot.2008.73 Nature Publishing Group Thomas D Schmittgen a , Kenneth J Livak b a Division of Pharmaceutics, College of Pharmacy, Ohio State University, Parks Hall b Applied Biosystems Abstract Two different methods of p...

Yersinia Diagnostic

Ivo Siegrist, Product Manager Microbiology ivo.siegrist@sial.com Yersinia are rod-shaped, Gram-negative facultative anaerobic bacteria. They exhibit fermentative metabolism and are oxidasenegative, mannitol-positive. A psychrophilic organism, Yersinia survives and proliferates at low temperatures of...

pLKO.1 Stability Assessed by Diagnostic Restriction Digestion

pLKO.1 Stability Assessed by Diagnostic Restriction Digestion Digestion of pLKO.1 library constructs by PvuII produces three fragments of 3.8 kb, 2.5 kb, and 0.8 kb. PvuII digestions of 244 library clones in pLKO.1 were performed following ten rounds of sequential copying and regrowth. No evidence o...

Long and Accurate PCR Amplification of DNA with RedAccuTaq D4812 Protocol

Reaction Optimization Reliable amplification of long DNA sequences requires: 1) effective denaturation of DNA template, 2) adequate extension times to produce large products and 3) protection of target DNA from damage by depurination. Effective denaturation is accomplished by the use of higher tempe...

Custom Next-Gen Sequencing Oligos Overview

Regardless of next-generation sequencing (NGS) platform, universal and index adapter sequences are required for the proper assembly of sample fragments. Adapters – especially index adapters since they contain the MID (multiplex identifier) or barcode – containing too high a proportion of truncated s...

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications. Phospholipids supplied as an organic solution should be stored in a glass container layered with argon or...

SAFC Cleveland, Ohio Facility

SAFC Cleveland is SAFC's Center of Excellence for biological buffers, cell culture media components and reagent compound manufacturing used in the biopharmaceutical and diagnostic industries. This chemical production facility consists of laboratory, intermediate and bulk chemical areas capable of pr...

DNA Labeling Guide

Within Roche, several labeling methods have been established. For example, DNA labeling is easy using PCR or choose in vitro transcription for your RNA applications. Alternatively, customers may choose nick translation when doing in situ hybridization. Learn more about different labeling methods and...

An Introduction to Antibodies: Generation of Antibodies

Antibody Formats Biological Effects of Antibodies Antibodies are normally produced by B cells, which are part of the immune system, in response to the introduction of foreign substances, such as infectious agents, into the animal’s body. The antibodies bind to the antigens that cause their generatio...

EnPresso® B 500 Animal-free Protocol

EnPresso® B is a pre-sterilized growth system designed to increase the yield of functional protein from E. coli-based expression systems. EnPresso growth systems provide optimal conditions for growth, metabolism and protein expression in microbial cultures. Protein yields are increased by enabling c...

Detection of Campylobacter spp. and Enterobacter sakazakii in food with a new test kit system

Related Links • Lateral Flow tests Kits • • Download PDF • Fabienke, Scanbec GmbH; Siegrist, Product Manager Microbiology, Sigma-Aldrich ivo.siegrist@sial.com Development of novel methods for a rapid, sensitive and reliable detection and quantification of microorganisms and pathogens in food, bevera...

SYBR® Green Extract-N-Amp™ Plant PCR Kit Protocol

Catalog Numbers: XNAPG The SYBR Green Extract-N-Amp Plant PCR Kit contains the reagents needed for rapid extraction, amplification and detection of genomic DNA from plant leaves. DNA is rapidly extracted from a piece of leaf tissue by incubation in Extraction Solution at 95 °C for 10 minutes. There ...