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Reversible addition-fragmentation chain transfer polymerizations(2)
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transformation(19)
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355 matches found for diseases

Development of Peptide-based Microarrays for Screening Antibodies from Patients with Autoimmune Diseases

• • Download PDF • Autoimmune diseases result from an overactive immune response against substances and cells normally present in the body. They include more than 80 widely varied chronic illnesses that affect 5-7% of the population, about two thirds of which are women. The symptoms affect almost ev...

Seaweed, kelp, bladderwrack (Fucus vesiculosus) | Plant Profiler

Synonyms / Common Names / Related Terms Algin, alginic acid, black-tang, bladder, bladder fucus, Blasen-tang, calcium, common seawrack, cut weed, Dyers fucus, Fucaceae (family), fucophorethols, Fucus, Fucus Plus®, Fucus vesiculosus, Hai-ts'ao, iodine, kelp, kelpware, knotted wrack, magnesium, Meerei...

Acetylcholine Receptors (Nicotinic)

Nicotinic acetylcholine receptors (nAChRs) constitute a family of ligand-gated channels, originally classified on the basis of their activation by the alkaloid nicotine, with acetylcholine (ACh) being the endogenous ligand. nAChRs are pentameric transmembrane proteins that form cationic channels per...

Autophagy and Mitophagy in Tumor Cell Survival and Death

Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle them. In mammalian cells, autophagy occurs constitutively at basal rates and its primary function is to...

Predictive Models for Neuroscience using CRISPR [VIDEO]

Related Links • Neuroscience • CRISPR • Latest CRISPR Research Caroline Beckett, the global CRISPR product manager for MilliporeSigma, discusses reagent solutions for creating predictive models for neuroscience research. She notes that many neuroscientists want to be able to create a predictive mode...

Long-term, live cell analysis of host-pathogen interactions using the CellASIC® ONIX System

Introduction Host-pathogen interactions represent a signifcant area of biomedical research, encompassing the study of how viruses, bacteria, and other organisms cause infections and diseases or alter normal physiology of host cells and tissues1. As the feld of cellular systems biology advances, ther...

Hybridoma Fusion Partners Cell Lines

Hybridoma technology involves the production of monoclonal antibodies specific to an antigen of interest. The somatic fusion of B lymphocytes of the spleen with immortal myeloma cells gives rise to a hybridoma cell line that can be perpetually propagated to produce clonally identical antibodies, as ...

AvaBridge ELISA Kit Protocol

Product Number. ABK0001 Complete kit for the systematic 3-D conformational comparability analysis of Avastin biosimilar molecule to Bevacizumab (Avastin trade name). Read the entire protocol before performing the assay. This kit is intended for research use only and not for use in diagnostic procedu...

Determination of L- and D-Lactic Acid Enantiomers by HPLC-MS-MS

Sensitive Determination of L- and D-Lactic Acid Enantiomers by HPLC-MS-MS The following was generated with the assistance of an outside source using Sigma-Aldrich products. Technical content was generated and provided by: H. Henry1, N. Marmy Conus2, P. Steenhout2, A. Benguin1, and O. Boulat1 1 Clini...

Coats disease
Synonyms
Species Human (1283)

A Fast and Reliable Method for Purity Analysis of Filgrastim

Related Products • Biopolymer Separations • BIOshell™ HPLC Columns • BIOshell™ Fused-Core® Columns Related Articles • Reporter US Volume 34.3 • High Resolution and High Efficiency Separations of mAbs and ADCs Using Proteomix HIC Columns • Improving the Chromatographic Separation of DMB-Labeled Siali...

Modified Cells for Enhanced R&D

Biowire Spring 2011 — Cell Lines — Models of Disease The use of human cell lines in research has been fundamental to our understanding of human biology, drug discovery, and the manufacture of vaccines. However, our ability to manipulate the genome of these cells to create better models of disease or...

EGF/EGFR signaling pathway

Background Epidermal Growth Factor Receptors (EGFR) and ligands Receptor activation EGFR Signaling Ras/Raf signaling cascade Phosphatidylinositol 3-kinase/Akt signaling cascade Signal transducers and activators of transcription (STAT) pathway Phospholipase Cγ signaling Nck/PAK signaling cascade Cbl ...

Adenosine Receptors

Adenosine receptors are members of the superfamily of G protein-coupled receptors and each bears the characteristic motif of seven transmembrane spanning domains. They fall into four known subtypes, referred to as A1, A2A, A2B and A3. Adenosine Receptors in Disease Research Modulation of adenosine r...

EuTc - Hydrogen Peroxide Quantification Agent

Europium-based dye Product number: 02816 for 100 reactions 1. Background Hydrogen peroxide (H2O2) is a reactive metabolic by-product that is a key regulator in a number of oxidative stress-related states. Functioning through NFkB and other factors, hydroperoxide-mediated pathways have been linked to...

Chitosan-based Biomaterials

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose. It is the primary, high modulus fibrous component of the exoskeleton of arthropods including crab, shrimp and lobsters, as well as some fungi. Structurally, chitin is an insoluble, linear,...

esiRNA Libraries Targeting Long Non-Coding RNA (lncRNA)

On this page: • Introduction to Non-Coding RNA • Product offering • Request a Quote or more information • In situ hybridization data • esiRNA specifications • How to Order • esiRNA controls • Reference Introduction to Non-Coding RNA Eukaryotic genomes contain both protein-coding and non-coding regio...

Analysis of Metabolites by HPLC

Related Articles Fast HPLC Using Fused-Core® Particle Technology for Rapid Screening of Pharmaceutical Compounds Serum Lipidomics Profiling using an Ascentis Express Fused-Core C18 Column Fast LC-MS-MS Analysis of 25-Hydroxyvitamin D2 and 25-Hydroxyvitamin D3 Alternative Retention and Selectivity Us...

FFPE Tissue

Archived Formalin-fixed, Paraffin-embedded (FFPE) tissue samples are invaluable resources for profiling gene expression and studying a variety of diseases. Since the archived DNA is usually available in limited quantities, amplification of the samples is essential. Amplifying the FFPE tissue can be ...

Leukotriene Receptors

Leukotrienes (LTs) exist as two distinct classes, hydroxyacids (such as LTB4), and cysteinyl leukotrienes (such as LTC4, LTD4 and LTE4). Leukotriene receptors have been classified into BLT and CysLT types to signify this basic level of selectivity, but there is also heterogeneity within both classes...

Trends in the Manufacturing of Viral Gene Therapeutics and Next Generation Vaccines

Jeff Strobel, Site Director, SAFC Carlsbad, CA Much of the technology used for the current manufacturing of viral vaccines has its roots in discoveries from the gene therapy industry. Gene therapy, or more correctly, gene transfer, is a catch-all phrase for those products which use a viral vector, p...

Functionalized Pei and Its Role in Gene Therapy

1Department of Pharmacy, Pharmaceutical Technology and Biopharmacy, Ludwig-Maximilians-Universität München, Butenandtstraße 5, 81377 München, Germany 2Nanosystems Initiative Munich (NIM), Ludwig-Maximilians-Universität München, Schellingstraße 4, 80799 München, Germany *Email: Olivia.merkel@lmu.de G...

Assessing Enriched Murine CD4+ T Cells Differentiated Towards Effector T Helper Cell Lineages

Cellular differentiation, the process by which progenitor cells differentiate into specialized cell types, is fundamental to developmental biology. In the immune system, immune progenitor cells must differentiate into diverse innate and adaptive phenotypes for the body to respond to infections. In t...

Agricultural Contaminants - Pesticide Classes & Exposure Hazards

(back to Agricultural Contaminants) Most pesticides contain an active ingredient or agent, synergists, solvents for dispersion and stabilization and adjuvants. Synergists enhance the killing power of the chemical agent. Adjuvants are additional additives, which may give many pesticides their competi...

Protein Of The Month June - Collagen | Europe

June: Collagen Origin: Collagen is the main component of connective tissue and it is the most abundant protein in mammals. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendons, ligaments and skin. Application: Commercial collagen is used as a substrate for s...

Sonic Hedgehog: Its dual role in morphogenic and mitogenic signaling

Related Links • Antibody Explorer: Search primary and secondary antibodies • Prestige Antibodies • Antibody Resource Center Mammalian Hedgehog proteins include Sonic Hedgehog (Shh), Indian Hedgehog (Ihh), and Desert Hedgehog (Dhh). They are involved in regulating pattern formation during embryonic d...

Clove (Syzygium aromaticum) | Plant Profiler

Synonyms / Common Names / Related Terms 2-methoxy-4-(2-propenyl)-phenol, Caryophylli atheroleum, Caryophylli Flos, caryophyllum, caryophyllus, Caryophyllus aromaticus, cengke, cengkeh, chiodo di garofano (Italian), choji, chor boghbojh, chor poghpch, cinnamon nails, clau, clavos, clou de girofle, Cl...

Cell Signaling & Neuroscience Literature

• Alzheimer's Disease Pathways poster • Cytoskeleton & Extracellular Matrix brochure • Gene Regulation and Chromatin Modification brochure • Ion Channel Solutions brochure • Ion Channels Technical brochure • Neurodegenerative Diseases brochure • Neuropsychiatric Disorders brochure • Tyrosine Kinases...

LC-MS Analysis of Vitamin D Metabolites

Vitamin D deficiency has become a topic of interest in recent publications.1-3 Vitamin D, along with calcium, promotes proper bone growth in children and aids in the prevention of osteoporosis in older adults. Vitamin D is present in two forms, Vitamin D3 and Vitamin D2. D3 is produced after ultravi...

Cranberry (Vaccinium macrocarpon) | Plant Profiler

Synonyms / Common Names / Related Terms Alpha-linolenic acid, American cranberry, anthocyanins, Arandano Americano, Arandano trepador, ascorbic acid, Azo-cranberry®, bear berry, benzoic acid, black cranberry, bog cranberry, catechins, cinnamic acids, citric acid, coumaroyl iridoid glycosides, ellagi...

Growth Factors in Stem Cell Biology

Related Links • Growth factors • 3D-cell culture • Organoids • Pluripotent Stem Cell Culture • Stem cell basics Related Products • Cell Culture Media and Reagents • Growth Factors • Stem Cell Antibodies • CRISPR Genome Editing • 3D Cell Culture • ECACC cell lines • 3DKUBE • 3D Hydrogels Growth facto...