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Acaricides(1)
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Atomic absorption spectroscopy(38)
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Buffers(19)
Building blocks(9)
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Reversible addition-fragmentation chain transfer polymerizations(2)
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transformation(19)
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346 matches found for diseases

Application Index: Complement Proteins

Overview Product List The Whole Complement Classical Pathway Assay Antibody Sensitization of Sheep Red Blood Cells Plasma & Blood Protein Resource The Complement System: Overview The complement system is a complex cascade involving proteolytic cleavage of serum glycoproteins often activated by cell ...

Adjuvant Research | BioFiles Volume 5 Number 3 Vaccine Adjuvants

BioFiles Volume 5, Number 3 — Vaccine Adjuvants Download BioFiles v5 n3 (2.2 Mb PDF) Table of Contents • Introduction • Adjuvant Research • New Approaches to Vaccine Adjuvants: Inhibiting the Inhibitor • Vaccine Media • Life Science Labware Syringes and Needles Dialysis Tubing Electrophoresis Adjuva...

New Approaches to Vaccine Adjuvants: Inhibiting the Inhibitor | BioFiles v5 n3 Vaccine Adjuvants

BioFiles Volume 5, Number 3 — Vaccine Adjuvants Download BioFiles v5 n3 (2.2 Mb PDF) Table of Contents • Introduction • Adjuvant Research • New Approaches to Vaccine Adjuvants: Inhibiting the Inhibitor • Vaccine Media • Life Science Labware Syringes and Needles Dialysis Tubing Electrophoresis New Ap...

Phosphatase Inhibitor Cocktail

• • Download PDF • Phosphorylation is a reversible protein post-translational modification. Protein kinases catalyze the transfer of the negatively charged γ-phosphate group from ATP to a hydroxyl side chain of serine, threonine or tyrosine residues of the protein, changing the protein’s conformatio...

Altered Lipid Metabolites in Aging

BioFiles Volume 5, Number 7 — Lipid Metabolism Download BioFiles v5 n7 (PDF) Table of Contents • Introduction • Natural Abundance Lipid Metabolites Glycerolipid Metabolsim Glycerophospholipid Metabolism Ether Lipid Metabolism Spingolipid Metabolism Fatty Acid Metabolism Terpenoid Metabolism Steroid ...

Sea buckthorn (Hippophae rhamnoides) | Plant Profiler

Synonyms / Common Names / Related Terms 5-formyltetrahydrofolate, 5-hydroxytryptamine, 5-methyltetrahydrofolate, acetic acid, aekol, alkaloids, almindelig havtorn (Danish), alpha-linolenic acid, amino acid, Amritscherl (German), anthocyanin, arabinose, argasse, argasse (French), argouse (French), ar...

Functionalized Pei and Its Role in Gene Therapy

1Department of Pharmacy, Pharmaceutical Technology and Biopharmacy, Ludwig-Maximilians-Universität München, Butenandtstraße 5, 81377 München, Germany 2Nanosystems Initiative Munich (NIM), Ludwig-Maximilians-Universität München, Schellingstraße 4, 80799 München, Germany *Email: Olivia.merkel@lmu.de G...

RNA isolation from blood, cultured cells, and animal or plant tissue on Whatman™ FTA™ cards

Whatman FTA cards are used for biological sample collection, storage, transport, and isolation of high-quality DNA for downstream applications. In the following studies, FTA cards were evaluated for their ability to collect, store, and isolate high-quality RNA from a variety of crude biological samp...

Tachykinin Receptors

The tachykinins represent a large family of peptides whose common structural feature is the C-terminal amino acid sequence Phe-X-Gly-Leu-Met-NH2. Substance P (SP), neurokinin A (NKA), neurokinin B (NKB), hemokinin-1, endokinin A and endokinin B are the major tachykinins found in mammals. They are en...

Coats disease
Synonyms
Species Human (1283)

Organelle Isolation & Analysis Kits

Enriching for organelles simplifies proteomic analysis and when partnered with protein pathway function allows key insight into development of healthy cell function as well as the disruption that leads to disease. The kits and reagents shown below enable researchers to enrich for functional mitochon...

miRNA (microRNA) Introduction

Mature microRNAs (miRNAs) are a class of naturally occurring, small non-coding RNA molecules, about 21–25 nucleotides in length. MicroRNAs are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to downregulate gene expression in a variety of manners, in...

ABC Transporters and Cancer Drug Resistance

• • Download PDF • Role of ABC Transporters and Multi-Drug Resistance Reversal Using RNA Interference (RNAi)* Chemotherapy is the treatment of choice against many types of cancer. However, over time chemotherapeutic drugs can become less effective due to the development of resistance that involves a...

Nuclear Receptors (Non-Steroids)

The receptors for several classes of non-steroidal compounds, including retinoids, thyroid hormones and vitamin D, also act as ligand-dependent transcription factors. In addition, a large number of receptors without known ligands have been discovered based on sequence homology, particularly in the D...

Enzyme Explorer Drug Metabolism Tech Review

Multi-Drug Resistance in Cancer - Role of ABC Transporter Proteins Balázs Sarkadi1, Gergely Szakás1,2 and András Váradi3 1. National Medical Center, Institute of Hematology and Immunology, Budapest, Hungary 2. National Cancer Institute, NIH, Bethesda, MD, USA 3. Institute of Enzymology, Hungarian Ac...

Webinar: iPSCs - The Future of Disease Research

Webinar Title: iPSCs - The Future of Disease Research Duration: 40 min Presentation + 20 mins for Q&A For over a decade, we have worked with the European Collection of Authenticated Cell Cultures (ECACC), a part of Public Health England, to bring authenticated and quality controlled cell lines and n...

Lipid Metabolism - BioFiles Volume 5, Number 7

BioFiles Volume 5, Number 7 — Lipid Metabolism Download BioFiles v5 n7 (PDF) Table of Contents • Introduction • Natural Abundance Lipid Metabolites Glycerolipid Metabolsim Glycerophospholipid Metabolism Ether Lipid Metabolism Spingolipid Metabolism Fatty Acid Metabolism Terpenoid Metabolism Steroid ...

Seaweed, kelp, bladderwrack (Fucus vesiculosus) | Plant Profiler

Synonyms / Common Names / Related Terms Algin, alginic acid, black-tang, bladder, bladder fucus, Blasen-tang, calcium, common seawrack, cut weed, Dyers fucus, Fucaceae (family), fucophorethols, Fucus, Fucus Plus®, Fucus vesiculosus, Hai-ts'ao, iodine, kelp, kelpware, knotted wrack, magnesium, Meerei...

FGFR

Fibroblast growth factors (FGFs) comprise a large family of signaling polypeptides. In the adult organism, FGFs are homeostatic factors and function in tissue repair and response to injury. In the embryo, FGFs regulate cell proliferation, migration, differentiation and survival. When inappropriately...

Isoprene Biosynthesis - Mevalonate and Non-mevalonate Pathways

The 5-carbon isomers isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) are the fundamental building blocks used to synthesize key biological isoprenoids (terpenoids) including cholesterol and other steroids, carotenoids, saponins, and limonoids. Two metabolic pathways exist for...

Phytochemicals

Download BioFiles v7 n6 (3.38 Mb PDF) Back to Dietary Bioactives homepage Throughout history, human populations have learned either by serendipity or by observation the properties of edible materials present in their environment. Even the most primitive societies often had a fairly sophisticated kno...

Boswellia (Boswellia carterii) | Plant Profiler

Synonyms / Common Names / Related Terms 11-keto β-boswellic acid, Acetyl-11-keto β-boswellic acid (AKBA), African elemi (Boswellia frereana), Arabian incense (Bakhour), Bibal incense (Boswellia carterii), birdwood, Bosweilla, Boswellia carterii, Boswellia carterii, Boswellia dalziellii, Boswellia fr...

Duolink® Webinars [VIDEOS]

• Introduction to Duolink and PLA Technology • Integrating the Proximity Ligation Assay (PLA) into your Research Program • Molecular Annotation of EGFR Signaling-Associated Complexes in Human Cancer • Visualizing DNA Methylation (5mC) on a Specific Genomic Locus (SEPTIN9) in Individual Human Cancer ...

Functional Foods

Download BioFiles v7 n6 (3.38 Mb PDF) Back to Dietary Bioactives homepage Beyond meeting essential nutritional needs, functional foods promote better health by reducing the risk of chronic disease such as coronary heart disease and cancer, improving cognitive health, and managing weight1. A popular ...

MystiCq® MicroRNA® Quantitation System

Technology Overview Workflow Background Protocols miRNA isolation cDNA synthesis miRNA qPCR Advanced information Product selection guides Troubleshooting MicroRNAs are small (22-24 nucleotide) non-coding RNA molecules that are important regulators of gene expression in a variety of eukaryotic organi...

HumiBridge ELISA Kit Protocol

Product Number. ABK0005 Complete kit for the systematic 3-D conformational comparability analysis of Humira biosimilar molecule to Adalimumab (Humira trade name). Read the entire protocol before performing the assay. This kit is intended for research use only and not for use in diagnostic procedures...

Leukotriene Receptors

Leukotrienes (LTs) exist as two distinct classes, hydroxyacids (such as LTB4), and cysteinyl leukotrienes (such as LTC4, LTD4 and LTE4). Leukotriene receptors have been classified into BLT and CysLT types to signify this basic level of selectivity, but there is also heterogeneity within both classes...

Discover Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Exposure to harsh conditions, cellular damage, and other factors can cause stress on cells. Stress attributed directly and indirectly to oxygen is referred to as oxidative stress, which is imposed on cells as a result of increased oxidant generation, decreased antioxidant protection, or failure to r...

Adult Human Stem Cells in Regenerative Medicine

BioFiles 2008, 3.11, 6. Dr. Gerhard Bauer Laboratory Director GMP Facility Adjunct Assistant Professor Stem Cell Program School of Medicine, University of California Davis Stem cell therapies offer hope to thousands of people suffering from diseases or injuries that destroy or damage vital cells and...

Nuclear Receptors (PPARs)

Peroxisome proliferator activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors that are related to retinoid, steroid and thyroid hormone receptors. PPARs play an important role in many cellular functions including lipid metabolis...

Bisphosphonates for Cancer Research

Sigma® is pleased to make these important compounds available to cancer researchers. Clodronate disodium salt (Dichloromethylenediphosphonic acid disodium salt) – Product No. D4434 Etidronate disodium salt – Product No. P5248 Alendronate sodium salt trihydrate – Product No. A4978 Pamindronate disodi...