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1094 matches found for high_performance_liquid_chromatography

Kava (Piper methysticum) | Plant Profiler

Synonyms / Common Names / Related Terms (+) -dihydrokawain-5-ol, 11-methoxy-5, 5-hydroxydihydrokawain, 6-dihydroyangonin, antares, ava, ava pepper, ava pepper shrub, ava root, awa, bornyl cinnamate, cavain, Fijian kava, flavokavines A and B, gea, gi, grog, intoxicating long pepper, intoxicating pepp...

Air Monitoring Literature

radiello® Brochure Publication Title Type Size (kb) No. Pages NEW Sampling and Analysis of Carbonyls in Air (request) Product Info - 16 ASSET™ EZ4-NCO Isocyanates Dry Sampler Product Info 400 2 General A Tool for Selecting an Adsorbent for Thermal Desorption Applications Product Info 529 36 Benefits...

Biodegradable Polymers

Related Articles • Dendritic Polyester Scaffolds for Drug Delivery Applications • Degradex® Microspheres and Nanoparticles for Drug Delivery Research and Formulation Development • Preparation & Staining of 3D Printed Tissues & Scaffolds • TokeOni: Properties and Applications • Dendrons and Hyperbran...

Enrichment of Phospholipids in Biological Samples Using HybridSPE-PL

Related Articles • Vitamin D epi-Metabolites Separated with HybridSPE-Phospholipid • Troubleshooting Analyte Recovery when Using HybridSPE-Precipitation Technology • Minimizing Phospholipid Matrix Effects using HybridSPE-PL • Phospholipid Removal Using HybridSPE™ Increases Assay Speed Phospholipids ...

LC/MS/MS Analysis of Aflatoxins in Hops After Solid Phase Extraction Cleanup

Related Products • Food & Beverage Analysis • Toxins (other than pesticide/drug residues) • Supel™ Tox SPE Cartridges Related Articles • Reporter US Volume 34.1 • Analysis of Residual Solvents in Hemp Extract by Headspace SPME-GC/MS • Headspace SPME GC/MS Analysis of Terpenes in Cannabis • Quantifyi...

Improvement in LC/MS Analysis of Vitamin D Metabolites in Serum by Leveraging Column Selectivity and Effective Sample Prep

Craig Aurand, Senior Application Chemist, craig.aurand@sial.com Clinical interest in vitamin D stems from its implications in an ever-widening range of human health conditions.1 This heightened interest has spawned the need for analytical strategies to assess an individual’s vitamin D status. Becaus...

Automation of PAMPA-Lipid using a MultiScreen-IP® PAMPA Filter Plate on a ScicloneTM ALH 3000 Advanced Liquid Handler Workstation

PAMPA-Lipid (Parallel Artificial Membrane Permeation Assay) is a non-cell based assay that utilizes a 96-well filter plate.1,2 The PAMPA assay is designed to predict passive transcellular permeability of drugs in early drug discovery. The assay is carried out in a 96-well MultiScreen-IP PAMPA filter...

Extraction and Analysis of PAHs in Olive Oil using Molecularly Imprinted Polymer SPE and GC-MS

Related Articles • A Comparison of Two Solid Phase Extraction Methods for the Analysis of Polyaromatic Hydrocarbons in Butter • Improved Recoveries and Lower Background for the Analysis of PAHs in Olive Oil • Chiral GC Analysis of Carvone Enantiomers in Essential Oils • Extraction and Analysis of PA...

Technical Literature for Derivatization Reagents

General Literature & Books Handbook of Analytical Derivatization Reactions – D. Knapp Guide to Derivatization Reagents for Gas Chromatography (GC) Handbook of Derivatization reagents for HPLC (Book & CD) - Lunn & Hellwig Silylation Reagents BSA (PDF 107 KB) BSA + TMCS (PDF 108 KB) BSA + TMCS + TMSI ...

LC/MS/MS Analysis of Lipophilic Marine Toxins in Shellfish According to EU Regulations on Ascentis Express C18

Related Products • Food & Beverage Analysis • Fused-Core Columns Technology • Marine Biotoxins Related Articles • Reporter US Volume 34.1 • Marine Biotoxin CRMs Marine biotoxins can be found worldwide in a variety of saltwater environments. They consist of lipophilic and hydrophilic compounds. These...

In Situ Hybridization of Whole-Mount Mouse Embryos with RNA Probes

Product lists for commonly used protocols from Cold Spring Harbor Protocols Thomas Lufkin This protocol was adapted from "Techniques for Visualizing Gene Products, Cells, Tissues, and Organ Systems," Chapter 16, in Manipulating the Mouse Embryo, 3rd edition, by Andras Nagy, Marina Gertsenstein, Kris...

A Universal Dual Peptide Assay for Antibody-Based Drug Candidates in Animal PK Studies Using a Full-Length Stable Isotope Labeled Internal Standard

There is a growing demand for reliable LC–MS/MS assays to support the bioanalysis of a human monoclonal antibody-based drug candidates in preclinical studies. Traditional LC-MS/MS assays rely on analyte specific stable isotope labeled (SIL) peptides that provide poor absolute quantitation due to lat...

Molecularly Imprinted Polymer SPE- Acid NSAIDs from Muscle

• • Download PDF • Related Articles • LC-MS of Illicit Bath Salts in Urine • Fast HPLC Using Fused-Core Particle Technology for Rapid Screening of Pharmaceutical Compounds • Metabolites – A Serious Challenge for LC/MS Separations and Usual Detection Techniques • Serum Lipidomics Profiling using an A...

Quick, Sensitive LC/MS/MS Analysis of Aflatoxins in Cannabis

Related Products • Cannabis Testing • Food & Beverage Analysis • Toxins (other than pesticide/drug residues) • Supel™ Tox SPE Cartridges Related Articles • Reporter US Volume 34.2 • Analysis of Residual Solvents in Hemp Extract by Headspace SPME-GC/MS • Headspace SPME GC/MS Analysis of Terpenes in C...

Ephedra (Ephedra sinica) | Plant Profiler

Synonyms / Common Names / Related Terms 6-hydroxykynurenic acid, amp II, amsania, brigham tea, budshur, cao ma huang (Chinese), cathine, chewa, Chinese ephedra, Chinese joint fir, D-pseudoephedrine, desert herb, desert tea, dextro-rotatory, EPH 833, Ephedra altissima, Ephedra americana, Ephedra anti...

OSHA 95– Products and Materials Guide

Ethylene Thiourea Ethylene thiourea is used as an accelerator in synthetic rubber production, a curing agent for epichlorohydrin elastomers, and component of ethylenebisdithiocarbamate fungicides. For this method, samples are collected open-face by drawing air through a four-piece sampling cassette ...

Characterization of Stable Isotope Labeled APO-A1 for Use as an Internal Standard in a Quantitative MS Workflow

Characterize heavy SIL-APOA1 (SILu™ Prot APOA1 Apolipoprotein A-I) for use in quantitative MS. The ideal internal standard for quantitative LC/MS assays would be a stable-isotope-labeled full-length protein that is equivalent to the native target protein which can be introduced at the beginning of t...

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more or less like a Y. Basic structure of the Ig monomer (Figure 1) consists of two identical halves conne...

Diagnostic Learning Center

Welcome to the learning center for Diagnostics. Follow the links below to watch our webinars on a variety of informative topics; review white papers on Unannounced Audits and other Industry Quality aspects; and discover what support is available for your company. Our extensive range of downloadable ...

Evaluation of Different Enzymes on Hydrolysis Efficiencies of Glucuronide Drug Metabolites in Urine

β-glucuronidase (GUS) enzymes are utilized to hydrolyze glucuronide (gluc) drug metabolites to the parent drug, facilitating analysis by LC-MS/MS. Here we evaluate the hydrolysis efficiency of β-glucuronidase derived from Patella vulgata (limpet), Helix pomatia (snail), Red abalone, and E. coli on d...

Avanti® FAQ

Drug Delivery / Pharmaceutical Applications • What are the differences between (advantages of) synthetic and natural phospholipids? • What are the advantages/disadvantages of including cholesterol in my liposomes? • How do I get my hydrophobic drug in the lipid membrane? • What issues should I consi...

Extraction of Nitroimidazoles from Milk and Eggs using Molecularly Imprinted Polymers

Related Articles • Aminoglycoside Analysis in Honey Using Molecularly Imprinted Polymer Cleanup and LC/MS/MS • Aminoglycoside Analysis in Pork Muscle using Molecularly Imprinted Polymer Cleanup and LC/MS/MS • Fast Extraction and Low Level Detection of Chloramphenicol in Shrimp • Selective Extraction...

Determination of L- and D-Lactic Acid Enantiomers by HPLC-MS-MS

Sensitive Determination of L- and D-Lactic Acid Enantiomers by HPLC-MS-MS The following was generated with the assistance of an outside source using Sigma-Aldrich products. Technical content was generated and provided by: H. Henry1, N. Marmy Conus2, P. Steenhout2, A. Benguin1, and O. Boulat1 1 Clini...

A Fast and Reliable Method for Purity Analysis of Filgrastim

Related Products • Biopolymer Separations • BIOshell™ HPLC Columns • BIOshell™ Fused-Core® Columns Related Articles • Reporter US Volume 34.3 • High Resolution and High Efficiency Separations of mAbs and ADCs Using Proteomix HIC Columns • Improving the Chromatographic Separation of DMB-Labeled Siali...

Ginkgo (Ginkgo biloba) | Plant Profiler

Synonyms / Common Names / Related Terms Adiantifolia, AKL1, arbre aux quarante écus, ArginMax®, bai guo ye, baiguo, BioGinkgo®, Blackmores Ginkgo Brahmi (Bacopa monniera), BN-52063, duck foot tree, EGb, EGb 761, Elefantenohr, Eun-haeng, facherblattbaum, Fossil tree, GBE, GBE 24, GBX, ginan, Gincosan...

Volatiles - Chromatography and Sample Prep Literature from Supelco

Pub. Id. Subject Type Size (KB) No. of Pages T400156 A Systematic Approach for Selecting the Appropriate Fiber Product Info 614 32 T494042 TO-14 Gas Standards Product Info 598 2 T495049 Supelco Chemical Standards for US EPA Method 8260A Product Info 94 2 IYP VOC's / BTEX chemically desorbed with CS2...

An LC/MS Peptide Standard for Rapid System Suitability Assessment and Retention Time Translation Across LC/MS Platforms

Related Products • Biopolymer Separations • BIOshell™ HPLC Columns • BIOshell™ Fused-Core® Columns • Tool for Mass Spectrometry Related Articles • Reporter US Volume 34.2 • High Resolution and High Efficiency Separations of mAbs and ADCs Using Proteomix HIC Columns • Improving the Chromatographic Se...

Chondroitinase for Neural Regeneration Research

Repairing the Information Highway Chondroitin-Related Reagents for Neural Regeneration Research The spinal cord is the information highway system for the brain. And axons are the road that allows information data to be transferred. So, when a traumatic spinal cord injury (SCI) occurs and axons are i...

Ultra-High Performance Liquid Chromatography (UHPLC) with the Ascentis Express Phenyl-Hexyl Column

Related Articles • Ascentis Express UHPLC Columns with 2.0 μm Fused-Core Particles • Separate Closely Related Compounds Using Ascentis Express F5 Columns • Benzodiazepines on Ascentis Express Phenyl Hexyl HPLC Columns • Ascentis Express RP-Amide HPLC Columns • Accelerated Bioanalytical LC/MS/MS Usin...

In Vitro Transporter Models for ADME-Tox Research Webinar

Drug transporters play a pivotal role in mediating the disposition of many drugs. As a result, researchers in the fields of drug discovery and development have shown a steadily rising level of interest in transporter-drug interactions, transporter-mediated drug-drug interactions, and the role of tra...