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196 matches found for hormones

Ultrapure Water for LC-MS Biomedical Analyses

In this paper the suitability of reagent water for LC-MS biomedical analyses will be evaluated and the role of water quality in achieving sensitive and reliable LC-MS analyses will be discussed. Furthermore, since quality assurance is one of the key requirements in the clinical laboratory, a modern ...

Immunohistochemistry: Current Applications in Breast Cancer

By: Mike Lacey, M.D. Recorded Webinar Immunohistochemistry (IHC) is used to characterize intracellular proteins or various cell surfaces in all tissues. Individual markers, or more often panels of various marker proteins, can be used to characterize various tumor subtypes, confirm tissue of origin, ...

Cell-Free Protein Synthesis/Expression (CFPS/CFPE)

A form of synthetic biology, cell-free protein synthesis is a rapid method to produce recombinant proteins in solution without involving cells. Using biomolecular translation machinery extracted from a range of different cell types, CFPS empowers researchers to express a protein of interest within a...

Immunohistochemistry: Current Applications in Gastrointestinal Cancer

Incidence Deaths Lifetime risk of Colorectal Cancer Signs and Symptoms Immunohistochemistry and Colon Cancer Metastatic Carcinoma [Webinar] Colorectal Cancer and Immunohistochemistry Materials References Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 ca...

Selection Guide for Polymeric Resins in Chromatography & Purification

Related Products • Adsorbent Media (Polymeric) • Cation Exchange Media Related Content • Adsorbents for use as Purification Media • Custom Resin Processing & Packaging • Custom Media, Columns, Cartridges for LPLC Sigma-Aldrich carries a vast array of resins, from leading manufacturers; such as, Dow ...

RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering

Karsten Mäder Institute of Pharmacy Martin-Luther-University Halle-Wittenberg, Germany Email: karsten.maeder@pharmazie.uni-halle.de The ability for synthetic polymers to degrade in a controlled manner was developed for environmental reasons in the late 1960s. Interest in utilizing biodegradable poly...

Authenticated Breast Cancer Cell Lines for Cancer Research

Related Links • Cell Culture • ECACC Cell Lines • Protocols for ECACC Cell Lines • Browse Breast Cancer Cell Lines Related Articles • Cancer Stem Cell Proliferation in Human Prostate and Breast Cancer Cell Lines Utilizing a New Defined Serum-Free 3D Spheroid Media • A New Cancer Biomarker Discovered...

Applications for Peptide ES-C18 Columns

A Breakthrough in Bioseparations Performance Applications - Peptides, Peptide Mapping, Small Proteins Ordering Information Peptide ES-C18 brochure (900 Kb PDF) Learn more about the Fused-Core Advantage Ascentis Express Peptide ES-C18 is a high-speed, high-performance liquid chromatography column bas...

GRKs

The superfamily of G protein-coupled receptors (GPCRs) contains upwards of 1000 distinct members that mediate the vast majority of responses to hormones, neurotransmitters, sensory stimuli, and various autocrine and paracrine factors. These integral membrane proteins have a conserved primary structu...

glycoprotein hormones, alpha polypeptide
Synonyms CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA
Species Human (1081) , Species Mouse (12640) , Species Rat (116700) , Species Zebrafish (402987) , Species dog (403483) , Species cow (280749) , Species domestic cat (751819) , Species chicken (421829) , Species Goat (100860817) , Species Domestic Rabbit (100009481) , Species sheep (443538) , Species domestic guinea pig (100135499) , Species naked mole-rat (101704979)
Summary: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Adenylyl Cyclase | Technical Article

Adenosine 3':5'-monophosphate (cAMP) modifies cell function in all eukaryotic cells, principally through the activation of cAMP-dependent protein kinase (PKA), but also through cAMP-gated ion channels and guanine nucleotide exchange factors directly activated by cAMP. Cellular levels of cAMP reflect...

Astragalus (Astragalus membranaceous) | Plant Profiler

Synonyms / Common Names / Related Terms Astragalosides I-IV, Astragalus gummifera, Astragalus lentiginosus, Astragalus membranaceus, Astragalus membranaceus japonica, Astragalus mollissimus, Astragalus mongholicus, astragalus polysaccharide, Astragalus propinquus, astragalus saponin, Astragalus trig...

Catecholamines

Catecholamines function as neurotransmitters and hormones within the body where they regulate and influence the activity of many complex physiological processes.1 Excessive production of catecholamines and their metabolites is a diagnostic indicator of catecholamine-producing tumors including phaeoc...

Calendula (Calendula officinalis) | Plant Profiler

Synonyms / Common Names / Related Terms Allo-ocimene, arnidiol -3-O-laurate, arnidiol-3-O-myristate, arnidiol-3-O-palmitate, Asteraceae (family), bride of the sun, bull flower, butterwort, calendasaponin A, calendasaponin B, calendasaponin C, calendasaponin D, Calendula arvensis L., calendula flower...

High Resolution Separation of Human Serum Albumin Tryptic Digest using Fused-Core HPLC Columns

Related Articles • Faster Protein and Peptide Liquid Chromatography: Introducing BIOshell Fused-Core HPLC Columns • Online SPE/LC-MS Method for the Rapid Analysis of Thyroid Hormones in Plasma Prof. Luigi Mondello University of Messina, Italy wayne.way@sial.com The last decades have witnessed the us...

Analysis of Fats (fatty acids, FAMEs, glycerides) in Food and Beverages

Related Articles • GC Analyses of Free Fatty Acids • Derivatization of Fatty acids to FAMEs • Fast GC Analysis of Detailed cis/trans Fatty Acid Methyl Esters (FAMEs) on the 75 m SP™-2560 Capillary Column • New cis/trans FAME Standard for Optimising GC System Performance Related Links • Nukol™ column...

Phospholipid Extractions for Cleanup or Enrichment

Within the last 5-10 years, hydrophilic polymer SPE phases have become the phase of choice when developing new extraction methods that recover, concentrate, and cleanup small molecules (e.g., pharmaceutical compounds) from complex aqueous sample matrixes (e.g., biological fluids, water, etc.). Unlik...

Adenylyl Cyclase - ADM

Adenosine 3':5'-monophosphate (cAMP) modifies cell function in all eukaryotic cells, principally through the activation of cAMP-dependent protein kinase (PKA), but also through cAMP-gated ion channels and guanine nucleotide exchange factors directly activated by cAMP. Cellular levels of cAMP reflect...

Cyclodextrin Solubility Table

Table includes the solubility of common cell culture components in water and in a solution of 2-Hydroxylpropyl β-cyclodextrin. Cyclodextrin is a non-toxic compound useful for its ability to solubilize fat soluble vitamins and hormones. Complete list of cell culture grade cyclodextrins Compound Solub...

Sanger Whole Genome CRISPR Arrayed Libraries

Designed by the Wellcome Trust Sanger Institute Free On-Demand Webinar: Let's Talk Lentivirus Sanger Arrayed Lentiviral CRISPR Libraries won prestigious R&D 100 Award We have joined forces with The Wellcome Sanger Institute to make the first ever arrayed lentiviral CRISPR knockout libraries for huma...

Supel-Select HLB SPE for Pharmaceutical Analysis

Related Articles UHPLC Analysis of Taxanes Using A Titan C18 Column and UV Detection Fast HPLC Using Fused-Core Particle Technology for Rapid Screening of Pharmaceutical Compounds Metabolites – A Serious Challenge for LC/MS Separations and Usual Detection Techniques Serum Lipidomics Profiling using ...

Serum free cancer cell line media

Historically, cancer cell lines have been cultured almost exclusively in culture media supplemented with significant amounts of fetal bovine serum (FBS). Like other undefined media supplements, fetal bovine serum has unwanted physiological, genetic and epigenetic cellular effects1-4 and is known to ...

Cyclodextrins

• • Download PDF • Many metabolically important compounds, such as lipid-soluble vitamins and hormones, have very low solubilities in aqueous solutions. Various techniques have been used to solubilize these compounds in tissue culture, cell culture, or other water-based applications. A frequently us...

Acetylcholine Receptors (Muscarinic)

Muscarinic acetylcholine receptors are members of the superfamily of G protein-coupled receptors (GPCRs). They are relatively abundant and mediate many of the diverse actions of acetylcholine in the CNS, as well as throughout non-nervous tissues innervated by the parasympathetic nervous system. Five...

Determination of Hydrocortisone from Topical Cream Using Discovery DSC-Si SPE and Reversed-Phase HPLC-UV

Related Products • Discovery DSC-Si SPE Products Related Articles • Parabens in Topical Preparations Using SPME-GC-MS Hydrocortisone (Figure A) is a steroid hormone secreted by the adrenal cortex and synthesized for medicinal use. It is a moderately polar compound that contains a glucocorticoid stru...

Certified Reference Materials

Sigma Aldrich offers a wide range of certified reference materials. With Cerilliant, RTC and Supelco, Sigma-Aldrich offers three in-house manufactured high quality CRM brands all produced under ISO/IEC 17025 and ISO Guide 34 double accreditation. In addition, we distribute certified reference materi...

Protocols for the Fmoc SPPS of Cysteine-containing Peptides

Related Links • Subscribe to Novabiochem Innovations • VIEW PRODUCT LIST Introduction Cysteinyl protection Fmoc SPPS using protected cysteine derivatives Synthesis of cysteinyl peptides Handling of sulfhydryl peptides Disulfide bond formation by oxidation of cysteinyl peptides Reduction of disulfide...

Sample Preparation & Purification in Analytical Chemistry & Chromatography

Our sample preparation and purification portfolio includes products for solid phase extraction (SPE), solid phase microextraction (SPME), air monitoring, sample decomposition, purge and trap techniques and flash chromatography and LPLC. Our comprehensive range features products for clinical, pharmac...

Hormone Standards

Over the past 17 years, hormone testing has increased significantly in the clinical laboratory setting as advances in the specificity and selectivity of LC-MS/MS technology have enabled hormones to serve as biomarkers for a variety of diseases from congenital disorders, heart disease, and psychiatri...

Mouse Embryonic Stem Cell Culture

• Transgenic Mouse Models • ESGRO Leukemia Inhibitory Factor • ES Cell Qualified FBS • Serum-Free/Feeder-Free Media • MEF Feeder Cells • Mouse Genotyping • Stem Cell Culture Protocols Transgenic and gene knockout technologies are powerful tools for studying gene function. A commonly used method for ...

Reporter - Supelco Chromatography newsletter

In publication since 1982, the Reporter newsletter provides information on our innovations and new products relating to HPLC, GC, Chiral Chromatography, Sample Preparation/Handling, and other chromatography topics. This 24-page print version is published 5 times a year, and contains full-length arti...