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    Search term:"ligands"

    621 matches found for ligands

    Gas Chromatography, Supelco Reporter 29.5

    EN 14110 (Determination of Methanol Impurity in B100 Biodiesel) Using SPME on the Equity-1 US EPA Method 8141 (Organophosphorous Pesticides) on the SLB-5ms and SPB-608 EN 14110 (Determination of Methanol Impurity in B100 Biodiesel) Using SPME on the Equity-1 back to top Katherine K. Stenerson and Mi...

    Palladium Catalysts: Pd(dmdba)2 and Pd EnCat™ Systems

    C–C coupling reactions are arguably the most powerful transformations in synthetic organic chemistry, as simple molecules can be expeditiously converted into architecturally diverse structures. Among C–C bond forming reactions, the great importance of palladium catalysts has encouraged scientists to...

    Vascular Endothelial Growth Factors (VEGF)

    • • Download PDF • Vascular endothelial growth factor (VEGF) is a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. Originally known simply as VEGF, vasculotropin (VAS) or vascular permeability factor (VPF), this factor ...

    Cross-coupling in Chemical Synthesis

    Cross-coupling has been an essential reaction for the past 20 years with its utilization increasing exponentially for the last 10 years. It has been used in the synthesis of a variety of products ranging from natural compounds to polymers. Products: • Chem Product Central™ • Catalysts and Ligands • ...

    Palladium-Catalyzed Reduction of Allylic Esters

    The palladium catalyzed reduction of allylic esters provides a convenient method to access chiral olefins.1Hayashi et al. studied the activity of the MOP ligand with palladium toward the reduction of allylic esters.2 Mechanistic studies of the reaction have showed that a monodentate phosphine ligand...

    Gel Filtration Chromatography

    Gel filtration chromatography seprarates proteins, peptides, and oligonucleotides on the basis of size. Molecules move through a bed of porous beads, diffusing into the beads to greater or lesser degrees. Smaller molecules diffuse further into the pores of the beads and therefore move through the be...

    CBHA Ligands

    Aldrich ChemFiles 2010, 10.1, 5. Yamamoto and his group developed a new type of ligands based on the C2-symmetric chiral bishydroxamic acid (CBHA). These bidentate ligands have pendant "arms" that can be substituted with a variety of substituents allowing for a finetuning of the ligand potency. A va...

    Chloride Channels

    From a functional viewpoint, several different types of chloride channels showing different electrophysiological and regulatory characteristics have been described. These can be loosely grouped into five categories: cAMP-, calcium-, volume- and voltage-activated chloride channels as well as ligand-g...

    ChemNavigator® 3DPL™(3-Dimensional Protein-Ligand Search)

    Mike Willis Market Segment Manager Mike Willis@sial.com back to top 3DPL Provides fast identification of targeted molecules 3DPL offers a rapid approach for selecting a population of targeted molecules from starting sets of millions of small molecule structures. 3DPL technology uses a protein struct...

    KIT ligand
    Synonyms FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7
    Species Human (4254) , Species Rat (60427) , Species Goat (100860807) , Species sheep (443371) , Species domestic guinea pig (100721734) , Species chicken (396028) , Species domestic cat (493937) , Species dog (403507) , Species Horse (100034127) , Species cow (281885)
    Summary: This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

    Molecular Layer Deposition of Organic and Hybrid Organic-Inorganic Polymers

    • • Download PDF • 1Department of Chemistry and Biochemistry and 2Department of Chemical and Biological Engineering, University of Colorado, Boulder, Colorado 80309 E-mail: Steven.George@Colorado.edu Steven M. George*1,2 and Byunghoon Yoon1 Atomic layer deposition (ALD) techniques have emerged in th...

    ChemFiles Colume 9 Article 6 - Cross Metathesis

    Cross metathesis has become an invaluable method for the preparation of olefins.1 While cross metathesis is typically conducted under mild conditions and is tolerant of a variety of functionalities, the chemo- and stereoselectivity of the reaction were more difficult to predict.2 However, due to adv...

    Hematopoietic Stem Cells Protocols

    Preparation of Mouse Embryonic Fibroblast (MEF) Feeder Cell Layer Culture of hES Cells Induction of hES Cell Differentiation Expansion of hES-blast Colony (BC) Cells Preparation of Mouse Embryonic Fibroblast (MEF) Feeder Cell Layer • Eviscerate 12.5 dpc ICR or CD-1 mouse embryos leaving the heads on...

    Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels

    Cyclic nucleotide-regulated cation channels are classified into two principal subfamilies, the cyclic nucleotide-gated (CNG) channels and the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. The two channel families differ from each other with regard to their mode of activation. C...

    Performing a Purification of IgG Antibodies with Protein G GraviTrap™

    Related Articles • Automated Purification of Antibodies Using ÄKTA Chromatography Systems • Column Packing and Preparation for Affinity Chromatography of Antibodies • Converting from Flow Velocity to Volumetric Flow Rates • Desalting and Buffer Exchange for Affinity Chromatography of Antibodies • Ge...

    Metal and Phosphine Mediated Transformations

    Functionalized allyl boronates are useful building blocks in natural product synthesis. Olsson et al. reported the use of a palladium pincer complex in combination with diboronic acid for the boronation of readily available allylic alcohols. Under mild conditions, a variety of allylic alcohols were ...

    Polydiacetylene Nanotubes (PDNTs)

    Polydiacetylene nanotubes (PDNTs) are self-assembled diacetylene nanotubes comprised of cross-linking of conjugated double and triple bonds. These PDNTs have remarkable properties which include uniform dimensional structures and responsive chromic characteristics that can be utilized as is, within a...

    (R)-(+)- and (S)-(-)-Stericol: New, Effective Chiral Auxiliaries

    Introduction Introduction of chirality in organic molecules through the use of auxiliaries is a basic strategy in organic chemistry. Chiral benzylic alcohols are of particular interest because they often afford useful levels of stereoselection and are generally easy to cleave. The enantiomers of 1-(...

    Stephen Buchwald Group – Professor Product Portal

    Professor Product Portal Index Professor Stephen Buchwald The Buchwald group has developed a series of highly active and versatile palladium precatalysts and biarylphosphine ligands used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. The ligands are electr...

    Abigail Doyle Group – Professor Product Portal

    Professor Product Portal Index Professor Abigail Doyle Research in the Doyle group focuses on two areas: nucleophilic fluorination and nickel catalysis. The Doyle group has developed several reagents that advance these research areas. In fluorination, 2-pyridinesulfonyl fluoride (PyFluor) can be use...

    Q-Phos | Chemfiles Volume 7 Article 5

    The use of electron-rich, sterically congested monodentate phosphine ligands, in conjunction with a metal precursor, has become a common paradigm in transition-metal-catalyzed coupling reactions. Developed by the Hartwig group, pentaphenyl(di-tert-butylphosphino)ferrocene (Q-Phos, Figure 1) has emer...

    KitAlysis™ High-Throughput Screening Kits

    In the high-pressure environment of discovery chemistry, time is everything. While general catalytic methods exist, substrate dependency makes it difficult to predict optimal conditions in practice. A thoughtful screening process is the best way to cover a large amount of chemical space quickly whil...

    BrettPhos Ligand Supported Palladium-Catalyzed C-O Bond Formation through an Electronic Pathway of Reductive Elimination: Fluoroalkoxylation of Activated Aryl Halides

    A Pd/N-heterocyclic carbene-based catalyst achieves the Sonogashira coupling of an array of functionalized, ?-hydrogen-containing alkyl bromides and iodides under mild conditions. By furnishing the first example of a nonphosphine-based palladium catalyst for cross-coupling unactivated alkyl electrop...

    Selective Protonation of Methyl Groups in Highly Deuterated Proteins

    Vitali Tugarinov Department of Chemistry and Biochemistry Center for Biomolecular Structure and Organization University of Maryland, College Park, Maryland 20742 Lewis E. Kay Departments of Molecular Genetics, Biochemistry and Chemistry University of Toronto Toronto, Ontario, Canada M5S 1A8, and Hos...

    Tutorial in Microelectronics and Nanoelectronics

    Related Products • Micro and Nanoelectronics products Related Articles • High-Sensitive Deep Tissue Imaging • Electronic & Biomedical Applications of SWNTs • Graphene Inks for Printed Electronics • PCBM-Based n-Type Semiconductors • Plexcore® Organic Conductive Inks • Ruthenium-based dyes for Dye So...

    DalPhos Ligands

    Professor Mark Stradiotto and coworkers at Dalhousie University have developed air-stable Dalphos, which contains the bulky di(1-adamantyl)phosphino [P(1-Ad)2] fragment. These chelating N,P ligands are useful for previously unprecedented Pd-catalyzed C-N and C-C bond formation. Both Me-DalPhos (Cat....

    Chiral Chromatography Columns, Reagents, Services & Resources

    Supelco's Chiral Services, Astec Chiral HPLC (& LC-MS) columns, Astec & Supelco Chiral GC columns, protein-based CSPs, derivatization reagents and mobile phase additives combine to make us a world-leader in the supply of products for chiral chromatography. Our reputed brands include Astec CHIROBIOTI...

    Sigma-Aldrich's Cell Signaling & Neuroscience Celltransmissions Newsletter Index 2004

    Index of Main Articles and Application Notes 2004, 2003, 2002, 2001, 2000 - 1998 Issue (PDF file size) Main Article Title Application Note June 2004 Vol. 20, No. 2 (1.13 mb) An Update on Ligands for Prostanoid Receptors pp.1-8 Improved Ex Vivo Expansion of Functional CD34+ Cells Using Stemline™ II H...

    Chiral Pyrrolidines

    Aldrich ChemFiles 2005, 5.4, 14. Chiral pyrrolidines are playing an important role both as chiral building blocks for auxiliaries as well as key structures relevant to biologically active substances. Sigma-Aldrich has a large selection of pyrrolidines and other heterocyclic building blocks for organ...

    MIDA-protected Boronate Esters

    • • Download PDF • Product Manager The Suzuki-Miyaura cross-coupling reaction is one of the most important and highly utilized reactions in organic chemistry, with applications in polymer science as well as in the fine chemicals and pharmaceutical industries. However, some classes of boronic acids a...

    P2 Receptors: P2X Ion Channel Family

    Once known as P2 purinoreceptors, surface receptors for extracellular nucleotides are now called P2 receptors. This subtle change in nomenclature reflects the more varied nature of nucleotidic ligands, other than those containing a purine moiety, that are capable of activating these surface receptor...