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372 matches found for metabolism

Quantitative Lipidomics Webinar

Duration: 60 minutes Session 1: November 20, 2019 at 4 PM Eastern Standard Time Session 2: November 21, 2019 at 9 AM Central European Time The dysregulation of lipid metabolism is known to be associated with malignancy and metastatic progression in colorectal cancer (CRC). However, a detailed survey...

Lipoic (thioctic) acid, in Cell Culture

Importance and uses of lipoic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures Non-protein bound lipoic acid (aka thioctic acid), is a water and lipid soluble disulfide fatty acid that can move across the cell membrane of lymphocytes and fibroblasts. ...

Webinar: Getting Your Buffers Right: How to Control the pH of Cell Culture Medium

Date: November 14, 2019 Duration: 60 minutes Session 1: 10:00 AM EST / 3:00 PM GMT Session 2: 2:00 PM CST / 8:00 PM GMT pH is a fundamental variable in culture media. It must be controlled by an appropriately formulated buffering regime because biological processes are exquisitely sensitive to acid-...

Stable Isotope Labeled Fatty Acids as Metabolic Tracers

Jennifer E. Lambert, Ph.D. Parks Group The University of Texas Southwestern Medical Center Elizabeth J. Parks, Ph.D. Associate Professor Departments of Clinical Nutrition and Internal Medicine The University of Texas Southwestern Medical Center Traditionally, cardiovascular disease (CVD) risk factor...

Ginkgo (Ginkgo biloba) | Plant Profiler

Synonyms / Common Names / Related Terms Adiantifolia, AKL1, arbre aux quarante écus, ArginMax®, bai guo ye, baiguo, BioGinkgo®, Blackmores Ginkgo Brahmi (Bacopa monniera), BN-52063, duck foot tree, EGb, EGb 761, Elefantenohr, Eun-haeng, facherblattbaum, Fossil tree, GBE, GBE 24, GBX, ginan, Gincosan...

Lipid Induced Insulin Resistance

• • Download PDF • Obesity is a well-established risk factor for the development of insulin resistance. Obesity is associated with the increased deposition of lipids in non-adipose tissue with subsequent decreases in insulin sensitivity. Currently, the mechanisms by which increased fat accumulation ...

Tools for Measuring Energy Expenditure

• • Download PDF • ISOTEC Stable Isotopes: Tools for Measuring Energy Expenditure (786 Kb PDF) D.A. Schoeller, Ph.D. Professor Department of Nutritional Sciences University of Wisconsin Madison, Wisconsin Water, a simple nutrient that is so ubiquitous in nature that it is easily forgotten and pushed...

EnPresso FAQs

Top Three Questions General topics E. coli cultures P. pastoris cultures Q. What are the most common reasons for lower than expected yield? • Use of incorrect closures leads to poor oxygenation (DO NOT USE aluminum foil, or plastic lids) • Overfilling of flask leads to poor oxygenation (maximum 10% ...

Mycotoxin Detection Kit

These standard solutions are used for mycotoxin detection in FDA regulated tests. Materials listed below are commonly used in food contamination testing. All products listed are FDA analytical standard solutions. Combinations of the below products can be used for calibration methods, recovery experi...

copper metabolism (Murr1) domain containing 1
Synonyms C2orf5, MURR1
Species Human (150684) , Species Mouse (17846) , Species Rat (289831) , Species Zebrafish (692293) , Species domestic cat (101101457) , Species cow (534683) , Species chicken (769006) , Species dog (403590) , Species domestic guinea pig (100731728) , Species sheep (101117656)
Summary: COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]

Stem Cell Culture Glossary and Terms

Related Products • EBiSC Human iPS Cell Lines • Custom Engineered iPSC Lines • Pluripotent Stem Cell Culture • Neural Stem Cell Culture • Mesenchymal Stem Cell Culture • Hematopoietic Stem Cell Culture • Stem Cell Protocols • MEF Feeder Cells • 3D Cell Culture • Cell Culture Media • Stericup® Media ...

Astec Chiral Chromatography Bibliography by Phase

Astec Cellulose Astec CHIRALDEX & Supelco DEX Astec CHIROBIOTIC & Macrocyclic Glycopeptides Astec CLC (Copper Ligand Exchange) Astec CYCLOBOND Astec P-CAP and P-CAP-DP Cyclofructans Copyright restrictions do not permit us to provide copies of the articles listed here. ASTEC Cellulose back to top Sup...

Hepatotoxicity/Cytotoxicity Assays

The hepatotoxicity/cytotoxicity assays provide a means to measure cell death due to the cytotoxic effect of a test compound. We provide hepatotoxicity/cytotoxicity assays for all small molecule formulations such as pharmaceuticals, industrial chemicals and consumer products. Our hepatotoxicity/cytot...

Stable Isotopes in Medical Imaging

Compounds labeled with stable isotopes are used in Magnetic Resonance Imaging to render visible metabolic changes in the body. The goal of this application is the early diagnosis and treatment of neuropsychiatric disorders, cancer, and other disease states. The use of stable isotopes in medical imag...

Khella (Ammi visnaga) | Plant Profiler

Synonyms / Common Names / Related Terms Ammi, Ammi daucoides, Ammi visnaga, Bischofskrautfruchte, bishop's weed, bishop's weed fruit, daucus visagna, false Queen Anne's lace, fruits de khella, germakellin, honeyplant, khellin, picktooth, Spanish toothpick, toothpick plant, visnaga, visnagae, Visnaga...

Mitochondrial Dysfunction and Metabolic Defects

• • Download PDF • BioFiles 2011, 6.4, 14. Defects in mitochondrial function are associated with insulin resistance in both human and animal studies. Insulin resistance is associated with a decrease in the number, oxidative capacity, size, and density of mitochondria. Understanding the mechanisms th...

Piperazines - Aldrich ChemFiles 2005, 5.5, 1.

Aldrich ChemFiles 2005, 5.5, 1. Sigma-Aldrich is pleased to offer the third installment of our Privileged Structures ChemFiles. This piece will focus on the piperazine scaffold. We will discuss application data, Sigma-Aldrich building blocks that have been highlighted in the recent literature, and t...

PEPscreen® peptides to study protein phosphorylation and kinase activity

Related Links • PEPscreen® Peptides Resources • Peptide Portfolio • Quotation Request • Order Now Protein phosphorylation events mediate key cellular signaling pathways, regulating diverse processes such as proliferation, metabolism, and apoptosis. In the human proteome, which numbers up to 23,000 p...

Hepatocyte Webinar

The liver is a key organ for drug metabolism and disposition, the focus of a number of novel therapeutic programs, and a target for a number of toxic chemicals and drugs. Thus, liver tissue and its associated cells are in high demand for both in vitro and in vivo applications, as well as predictive ...

The Role of Liver Transporters in Drug-Drug Interactions

• Oral drug delivery involves dissolution in the small intestine and absorption across the enterocyte barrier into the portal vein followed by subsequent delivery through the liver into the systemic circulation. The liver therefore plays a vital role in all aspects of drug disposition, including abs...

In Vitro Safety Systems - ADME, DMPK, Tox

For ADME/Tox & DMPK scientists, performing Tier1/Tier2 safety testing assays, we provide more predictive in vitro model systems for intestine, liver, and kidney with primary, wild type and engineered cell lines, addressing transporters and nuclear receptors related to cyp induction, listed in the FD...

Basal Salts for Cell Culture

Dulbecco's Phosphate Buffered Saline Earle's Balanced Salts Hanks' Balanced Salts Tyrode's Salts Other Salt Mixtures Families of basal salt solutions are often named for their physician or scientist inventor. In 1885, Sydney Ringer developed a solution of inorganic salts designed to maintain contrac...

Astec CYCLOBOND™ Chiral HPLC Column Literature References

Astec Products | Technical Resources 1. New HPLC Column Technology: Inclusion Complexing, THE ASTEC INFORMER, Volume 4, Issue 1 (1984). 2. HPLC Inclusion Complexing - An Update, THE ASTEC INFORMER, Vol. 4, Issue 2, (1984). 3. Armstrong, D.W., DeMond, W., Cyclodextrin Bonded Phases for the Liquid Chr...

Gumweed (Grindelia squarrosa) | Plant Profiler

Synonyms / Common Names / Related Terms Asteraceae (family), August flower, California gumplant, grindelia, Grindelia camporum, Grindelia robusta, Grindeliae herba, Grindelie, gum plant, gumplant, gum weed, hardy grindelia, rosin weed, scaly grindelia, tar weed, tarweed. Mechanism of Action Pharmaco...

The Importance of Ion-Exchange Capacity in Mixed-Mode SPE

Most researchers who use SPE to process biological samples rely on traditional single-mode retention mechanisms to recover, clean up, and concentrate their compounds of interest prior to LC or GC analysis. Although single-mode SPE chemistries are often adequate, problems can easily arise. For exampl...

Eyebright (Euphrasia officinalis) | Plant Profiler

Synonyms / Common Names / Related Terms Adhib, ambrosia, augentrost, Augentrostkraut (German), Augstenzieger, briselunettes (French), casse-lunette (French), clary, clary wort, clear eye, eufragia, eufrasia (Italian), Euphraise, Euphraisiaeherba, Euphraisiae herbal (eyebright herb), Euphrasia, Euphr...

Quality Control Considerations in Cell Culture

Related Links • Cell Culture Homepage • Fundamental Techniques in Cell Culture- ECACC Handbook • ECACC Cell Lines • Fetal Bovine Serum • Classic Media and Salts • Cell Culture Reagents • Cell Culture Supplements • Stericup® Media Filtration • Primary Cell Culture • Stem Cell Culture • 3D Cell Cultur...

Andrographis (Andrographis paniculata) | Plant Profiler

Synonyms / Common Names / Related Terms Andrographolide, Chuan Xin Lin, Green chiretta, Kalmegh leaf extract, Kan Jang®, King of Bitters, Kold Kare®, Remdex®. Mechanism of Action Pharmacology: • Constituents: Andrographolide, a diterpene lactone compound, is believed to be the principal active agent...

Trace Level Analysis of NNAL in Urine Using SupelMIP™ SPE – NNAL and LC-MS-MS

Related Articles • Fast Extraction and Low Level Detection of Chloramphenicol in Shrimp Olga Shimelis, Anna-Karin Wihlborg*, Craig Aurand, and An Trinh an.trinh@sial.com *MIP Technologies AB, Lund, Sweden Tobacco-specific nitrosamines (TSNAs) are created through the burning, curing, and fermentation...

Sweet basil (Ocimum basilicum) | Plant Profiler

Synonyms / Common Names / Related Terms Apigenin, basil, citral, common basil, estragole, eugenol, geraniol, Lamiaceae (family), linalol, linolen, methylchavikol, methylcinnamat, Ocimum, Ocimum basilicum, Ocimum basilicum var. citratum, rosmarinic acid, Thai basil, ursolic acid. Bioactive products f...

Mitochondrial Stress and ROS

Oxidative stress is implicated in the pathogenesis of lipotoxicity in both animal and human studies. Chronic oxidative stress is linked to insulin resistance in multiple tissues. Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled ...