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310 matches found for microscopy

A Tissue Dictionary for Normal and Cancer Tissues: A complimentary tool for the Human Protein Atlas

Download the poster (574 Kb PDF) The Human Protein Atlas project was initiated in 2003 to establish a systematic high-throughput generation of affinity-purified polyclonal antibodies towards all human proteins and to use these antibodies to map protein localization within the human body. Protein exp...

Nanofluids for Biomedical Applications Using Spherical Iron Oxide Magnetic Nanoparticles Fabricated by High-Power Physical Evaporation

A. P. Safronov,1,2 I. V. Beketov,1,2 O. M. Samatov,1 G. V. Kurlyandskaya,2,3,* S. M. Bhagat,4 A. Larrañaga,5 I. Orue,5 R. Andrade5 1Institute of Electrophysics, RAS, Amundsen St. 106, 620016, Ekaterinburg, Russia 2Ural Federal University, Lenin St. 51, 620000, Ekaterinburg, Russia 3 Department of El...

Whole Genome Amplification for Single Cell Biology - Technical Article

The ultimate biological unit lies within a single cell. Many biological disciplines have taken aim to elucidate the causes of cellular differentiation at this level. The secret triggers that signal human maturation, regeneration and genetic diseases all lie buried in a single cell that was originall...

Cyst Formation of MDCK Cells in TrueGel3D™ Hydrogels

Related Links • 3D cell culture • 3D hydrogels • TrueGel3D™ hydrogels • Biomaterials Related Products • Cell culture • 3D cell culture • ECM proteins • 3D Scaffolds • 3D hydrogels Improved cell culture techniques from 2D to 3D have provided models that more closely mimic the native physiological con...

Use of Peptide Libraries to Investigate the Evolutionary Preservation of Antimicrobial Properties of Complement Peptide C3a from Invertebrates to Humans

• • Download PDF • Proteins that are essential to the survival of an organism are often structurally or functionally conserved to some extent throughout evolution. An example of an evolutionary old molecule is the C3 complement factor that is found both in modern day humans as well as in the horsesh...

Micro- and Nanofabricated Biomaterials for the Study of Cells and Microtissues

Phin Peng Lee, Karen E. Samy, Miquella G. Chavez, Alec Cerchiari, Tejal A. Desai* Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94158 USA *Email: tejal.desai@ucsf.edu Biomaterials science involves the design and fabrication of smart ...

Cell Culture Collections: Exploring the Iceberg

Biowire Spring 2011 — Cell Lines — Models of Disease Cell line misidentification and Mycoplasma contamination are well known as the greatest risks to any practitioner of cell culture1,2. Biological resource centers such as the European Collection of Cell Cultures (ECACC®) exist to ensure that life s...

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more or less like a Y. Basic structure of the Ig monomer (Figure 1) consists of two identical halves conne...

Super-Resolution Microscopy - Nanoscopy

Watch our video and learn more about Tools for Super-Resolution Microscopy Growth cone at the tip of the axon of a primary hippocampal neuron at 1 day in vitro imaged with the Abberior Instruments Expert Line STED microscope. Microtubules Tuj1 (red, Abberior STAR580) are bundled in the central-domai...

actin-related protein T2
Synonyms ARPM2, ARPT2, Arp-T2, HARPM2
Species Human (140625) , Species Mouse (73353) , Species Rat (298671) , Species chicken (428178) , Species cow (515214) , Species domestic cat (101087248) , Species dog (479581) , Species domestic guinea pig (100724608) , Species naked mole-rat (101722284) , Species sheep (101102916)
Summary: The protein encoded by this intronless gene belongs to the actin family. Studies have shown that this protein may be involved in cytoskeletal organization similar to other cytoplasmic actin-related protein (ARP) subfamily members. Antibody raised against the human protein has been used to detect the protein by immunoblotting and immunofluorescence microscopy, demonstrating its specific synthesis in the testis, late in spermatid differentiation, and its localization in the calyx. [provided by RefSeq, Jul 2008]

Cytology Products for Greater Accuracy and Lab Efficiency

Cytology is the study of the structure and function of cells under the microscope. Cytological techniques are commonly used to diagnose and differentiate tumors, inflammatory and other degenerative diseases. To support you in accurately and efficiently collecting and discerning cytological samples, ...

Sigma Life Science Online Product Catalog

Biochemicals & Reagents • Amino Acids • Antibodies • Antibiotics • Biological Buffers • Carbohydrates • Detergents • Enzymes, Inhibitors, and Substrates • Life Science Labware • Lipids • Peptides • Proteins & Derivatives • Stable Isotopes • Additional Biochemicals & Reagents Techniques & Application...

Immunohistochemistry: Current Applications in Gastrointestinal Cancer

Incidence Deaths Lifetime risk of Colorectal Cancer Signs and Symptoms Immunohistochemistry and Colon Cancer Metastatic Carcinoma [Webinar] Colorectal Cancer and Immunohistochemistry Materials References Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 ca...

Duolink® Proximity Ligation Assay (PLA) Multicolor Kits for Sensitive Multiplex Detection

Protein-protein interaction events Interacting proteins often function as key components in the initiation and cascade of inter-and intracellular communications and influence a large variety of cellular functions and behaviors. However, accurately identifying protein-protein interactions in fixed ti...

Micro and Nanometer Scale Photopatterning of Self-Assembled Monolayers

Graham J. Leggett* Department of Chemistry, University of Sheffield, Brook Hill, Sheffield S3 7HF, United Kingdom *Email: Graham.Leggett@shef.ac.uk Self-assembled monolayers (SAMs) have attracted enormous interest for a wide variety of applications in micro- and nano-technology. In this article, we ...

Simplicon™ In Vivo Protein Expression System

Simplicon™ is a novel system that generates immediate, high-sustained protein expression of multiple genes into transfected human cells without the risk of genome integration. The technology employs a single, synthetic, polycistronic, self-replicating RNA based on the Venezuelan equine encephalitis ...

Cell Migration & Invasion Assays

The Boyden Chamber Assay Cell Migration Assays Cell Invasion Assays Microfluidic Migration Device In Vitro Scratch Assay ECM Proteins References Metastasis is the cumulative result of multiple changes in tumor cells and their microenvironment that enables cellular migration and invasion into healthy...

Roche Transfection Database

X-tremeGENE™ Transfection Reagents from Roche have been used for a wide range of applications and a vast array of cell lines, primary cells and stem cells. Use the table below to find the right product for your experiment. To request a citation for a cell type on this list, please contact our techni...

Microparticles Learning Center

• Coupling to Microparticles Protocol • Determination of particles number • Microparticle Handling & Storage • Microparticle Quality Assurance • Microparticles in Microscopy Protocol • Synthesis & Properties of Microparticles • Washing Microparticles by Centrifugation-Protocol • References

Flexible Organic Transistors for Biomedical Applications

Tsuyoshi Sekitani,* Kazunori Kuribara, Tomoyuki Yokota, Takao Someya Department of Electric and Electronic Engineering, Department of Applied Physics, School of Engineering University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan Exploratory Research for Advanced Technology (ERATO) Japan S...

Fluorescent Nanodiamond Particles Containing Color Centers: Properties and Applications

Nanodiamond (ND) particles are increasingly being utilized as diagnostic, imaging, and therapeutic agents in biomedicine,1 for cryptography and quantum computing in quantum information processing, and as single-spin sensors in nanomagnetometry.2,3 Most of these applications are based on the unique o...

A New Cancer Biomarker Discovered

Cancer is a common disease and a major cause of death in the Western world. In general, incidence rates increase with age for most cancer forms. As human populations continue to live longer due to an improvement of the general health status, cancer will affect an increasing number of individuals. A ...

Chitosan Microparticles

Véronique Maquet, Sandrine Gautier KitoZyme, Rue Haute Claire 4, 4040 Herstal, Belgium • Introduction • Materials & method • Results • Conclusion Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of thi...

FSL Construct Protocol

The following protocol describes the generic procedure for the insertion of FSL constructs (Figure 1) into biological membranes. For simplicity the protocol will only refer to cells (kodecytes), which are at a 100% concentration. However, the term cells is interchangeable with virions (kodevirions) ...

Live Cell Calcium Indicators

Calcium ions (Ca2+) play vital cellular physiology roles in signal transduction pathways, in neurotransmitter release, in contraction of all muscle cell types, as enzyme cofactors, and in fertilization. Extracellular calcium is also important for maintaining the potential difference across excitable...

Fluorescent Dye Wavelength Index

Fluorescent dyes are used to tag proteins, nucleic acids, and other biomolecules for use in life science applications, including fluorescence microscopy, flow cytometry, fluorescence in situ hybridization (FISH), receptor binding assays, and enzyme assays. Using the right combination of fluorescent-...

NIR Fluorescence Dyes

• • Download PDF • An increasing demand for red emitting fluorescent dyes, useful in life science applications such as antibody and protein labeling, prompted us to develop new improved long wavelength markers for use in the visible/near-infrared (NIR) region. Tracy 645 and Tracy 652 (see Table 1) a...

Tissue Diagnostics Solutions

Discover our comprehensive product range for your complete clinical tissue diagnostics workflow. From consistent routine and special stains, to reliable Cell Marque™ IHC primary antibodies, universal reagents, control slides and cell lines, we provide the efficient, precision histology solutions you...

Etch-Resistant Block Copolymers

Material Matters 2006, 1.1, 6. Prof. Padma Gopalan Department of Materials Science and Engineering, University of Wisconsin, Madison, WI Prof. Shu Yang Department of Materials Science and Engineering University of Pennsylvania, Philadelphia, PA Block copolymers offer a means of combining the desirab...

Innovative Products & Tools for Cancer Research

We are committed to help predict cancer with novel discovery tools, characterize cancer with proven platforms, and drive cancer therapeutics through approval and production. As a company with a robust cancer research division, we know what works. Researchers are stronger in the fight with an oncolog...

CompoZr® Zinc Finger Nucleases FP-ZFN-IDLV

CompoZr Zinc Finger Nucleases (ZFNs) are a class of engineered DNA-binding proteins that facilitate highly specific targeted editing of any genome by creating double-stranded breaks in DNA at user specified locations. You can use ZFNs to create your choice of stable genetically engineered cell lines...