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23 matches found for morphogenesis

Cultrex® 3-D Culture Matrix™ Rat Collagen I Protocol

Product Number 3447-020-01 3-D Culture is an innovative approach to modeling the morphological effects of early oncogenesis on three-dimensional microenvironments. When healthy, differentiating cells exhibit a structured, polarized morphology that is critical for cellular formation and function. Dur...

Met

The Met family of receptor tyrosine kinases (RTKs) contains two members in mammals, referred to as Met and Ron. Met is the receptor for hepatocyte growth factor/scatter factor (HGF/SF), while Ron is the receptor for macrophage stimulating protein (MSP). In the adult, Met is predominantly expressed i...

Authenticated Breast Cancer Cell Lines for Cancer Research

Related Links • Cell Culture • ECACC Cell Lines • Protocols for ECACC Cell Lines • Browse Breast Cancer Cell Lines Related Articles • Cancer Stem Cell Proliferation in Human Prostate and Breast Cancer Cell Lines Utilizing a New Defined Serum-Free 3D Spheroid Media • A New Cancer Biomarker Discovered...

HyStem™ Glossary of Terms

A | B | C | D | E | F | G | H | I | L | M | N | O | P | R | S | T | U A Acinus (plural: acini) - The word comes from the latin word “grape”. It refers to the sac-like termination of a secretary exocrine gland. In vitro, mammary epithelial cells cultured in a laminin-rich matrix form acinus-like sphe...

Lemongrass (Cymbopogon) | Plant Profiler

Synonyms / Common Names / Related Terms Abafado (Portuguese), alpha-citral, alpha-terpineole, Andropogon citratus, Andropogon nardus, bai mak nao (Lao), beta-citral (neral), beta-myrcene, bhustrina (Indian), British Indian lemongrass, capim-cidrao, carene-2, caspase-3, Ceylon citronella grass, citra...

STE20

The Ste20 (Sterile 20) protein kinase family consists of enzymes with sequence homology to the yeast MAP4K Ste20p in the pheromone response pathway. Based on phylogenetic relationships, they can be divided into two subfamilies: PAK (p21-activated kinase) and GCK (germinal center kinase). The PAKs in...

Immunohistochemistry: Current Applications in Gastrointestinal Cancer

Incidence Deaths Lifetime risk of Colorectal Cancer Signs and Symptoms Immunohistochemistry and Colon Cancer Metastatic Carcinoma [Webinar] Colorectal Cancer and Immunohistochemistry Materials References Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 ca...

Hepatocyte Growth Factor (HGF)

• • Download PDF • Hepatocyte growth factor (HGF) is a potent mitogen for hepatocytes and a variety of other cells, including endothelial and epithelial cells, melanocytes, and keratinocytes. It also mediates epithelial morphogenesis. HGF is the ligand for a receptor encoded by the c-met proto-oncog...

Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts

Nature Protocols Volume 2 Issue 2, 22 February 2007, Pages 287 - 295 doi: 10.1038/nprot.2006.478 Nature Publishing Group Christian Frezza a , Sara Cipolat a , Luca Scorrano a a Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine Abstract Mitochondria participate in key metabolic re...

dishevelled associated activator of morphogenesis 1
Synonyms
Species Human (23002) , Species Mouse (208846) , Species Rat (314212) , Species chicken (423532) , Species dog (490714) , Species domestic cat (101098546) , Species Horse (100051203) , Species cow (513742) , Species domestic guinea pig (100719981) , Species naked mole-rat (101726077) , Species sheep (101123636)
Summary: Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012]

Cracking the Cancer Code

Biowire Spring 2011 — Cell Lines — Models of Disease Subscribe to Biowire and eBiowire Download Biowire Spring 2011 (7.0 Mb PDF) Biowire Spring 2011 Home Few words can be as terrifying. And that apprehension, once confined to conversations in the clinic, has gone on to pervade our collective health ...

3D Bioprinting: Bioink Selection Guide

3D bioprinting enables the generation of precisely controlled 3D cell models and tissue constructs, by engineering anatomically-shaped substrates with tissue-like complexity. Due to the high degree of control on structure and composition, 3D bioprinting has the potential to solve many critical unmet...

Why Optimize ECM? - Learning Center

Matrix Optimization is Crucial | Matrix Role in Mammary Epithelial Cell Differentiation | Matrix Role in Kidney Ureteric Bud Morphogenesis Matrix Stiffness Helps Determine a Stem Cell's Fate | Co-optimization of Matrix and Medium | References Matrix Optimization is Crucial Each different cell type i...

Cyst Formation of MDCK Cells in TrueGel3D™ Hydrogels

Related Links • 3D cell culture • 3D hydrogels • TrueGel3D™ hydrogels • Biomaterials Related Products • Cell culture • 3D cell culture • ECM proteins • 3D Scaffolds • 3D hydrogels Improved cell culture techniques from 2D to 3D have provided models that more closely mimic the native physiological con...

TRC Library Citations

Publish Sooner When You Partner with the MISSION® shRNA Team! The MISSION® TRC1.5 human and mouse shRNA libraries are the proven performers for small-scale to high-throughput RNAi screening. Below you will find a selection of papers where researchers have published in peer-reviewed journals using th...

Src

Since the isolation of v-Src as the transforming component of Rous sarcoma virus, and the subsequent identification of its cellular homolog c-Src, there has been intense interest in its activity and regulation. Src is the founding member of a group of non-receptor protein tyrosine kinases termed the...

Collagen Usage Recommendations

Collagen is one of the most abundant proteins in the connective tissues and internal organs of mammals. It provides the tensile strength of the extracellular matrix (ECM). It is classified into a number of structurally and genetically distinct types. Although different types of collagen exist, they ...

Attachment Factors for 3-Dimensional Cell Culture

Attachment Factors in Three-dimensional (3D) Matrices: Aspects in Tissue Engineering Author: Efrat Manaster, Ph.D. Sigma-Aldrich Research Technical Service, Jerusalem, Israel Three-dimensional (3D) extracellular matrix-based cell culture systems are being used as research tools for understanding nor...

EGF Signaling: Tracing Cancer's Path

The epidermal growth factor (EGF) family is a group of structurally related proteins that regulate cell proliferation, migration and differentiation via tyrosine kinase receptors on target cells. The EGF receptor has a cytoplasmic tyrosine kinase domain, a transmembrane domain and an extracellular d...

Glycosaminoglycan Sulfation and Signaling

• • Download PDF • Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units. The disaccharide units that are the basis of all glycosaminoglycans (except keratan) are a combination of an uronic acid (either glucuronic acid or iduronic acid) and an amino sugar (e...

Abl

The Abl family of non-receptor linked tyrosine kinases relay signals from diverse stimuli to promote changes in cell morphogenesis, migration, adhesion, proliferation and survival. Two Abl family kinases are found in vertebrates: Abl and the Abl-related gene (Arg, also known as Abl2) and homologs in...

Protease Inhibitor Cocktails References

Our portfolio of protease inhibitor cocktails are frequently cited in peer-reviewed scientific literature, suggesting their superior quality and excellent track record. This page lists a sampling of those research papers. Other citations are available under the specific product pages for each of our...

Ret

The human RET (REarranged during Transfection) gene maps on chromosome 10 q11.2 and codes for a single-pass transmembrane protein. Its extracellular portion contains four cadherin-like repeats, a calcium-binding site and a cysteine-rich domain. The intracellular portion features a typical tyrosine k...

Read the latest developments in CRISPR research

read abstract Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes Adriana CarolinaGonzalez1MichaelaSchweizer2SebastianJagdmann1ChristianBernreuther3ThomasReinheckel4PaulSaftig1MarkusDamme15 23-01-2018 Variants in the phospholipase D3 (PLD3) gene have genetically been linked to late...