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258 matches found for transformation

cataCXium® - Ligands and Complexes for Efficient Cross-Coupling Reactions

Introduction Cross-coupling reactions are an important class of catalytic transformations with applications in polymer science as well as in the fine chemicals and pharmaceutical industries. The use of aryl chlorides for these transformations is preferred due to their low cost and their availability...

Ginseng (Panax ginseng) | Plant Profiler

Synonyms / Common Names / Related Terms Ginseng (American ginseng, Asian ginseng, Chinese ginseng, Korean red ginseng, Panax ginseng:Panaxspp., includingP. ginsengC.C. Meyer andP. quinquefoliusL., excludingEleutherococcus senticosus), Acetylenic alcohol, acidic polysaccharides, acupuncture-moxibusti...

Metal Borohydrides as Hydrogen Storage Materials

• • Download PDF • General Electric Global Research To meet current DOE targets outlined in the article by S. Satyapal et al. in this issue, the materials for hydrogen storage should possess high hydrogen content, low heats of dehydrogenation (to minimize the energy penalty), and fast kinetics of hy...

Introduction to Transfection - Transfection Reagents

Transfection involves the introduction of DNA or RNA into eukaryotic cells and is used in research to study and modulate gene expression. Thus, transfection techniques serve as an analytical tool that facilitates the characterization of genetic functions, protein synthesis, cell growth and developme...

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Download (1MB) Palladium catalyzed cross-coupling reactions have revolutionized the way in which molecules are constructed. From the fields of organic synthesis and medicinal chemistry, to materials science and polymer chemistry, cross-coupling has impacted multiple areas of science. The field of cr...

Applications with REDTaq

Introduction Reagents Results and Discussion Conclusion Materials References Since its introduction, REDTaq has been well received by the scientific community. The original product idea was to add convenience to PCR by formulating a reaction that also contained loading buffer and dye. The end produc...

Introduction to Blue-White Screening

Blue-white screening is a rapid and efficient technique for the identification of recombinant bacteria. It relies on the activity of β-galactosidase, an enzyme occurring in E. coli, which cleaves lactose into glucose and galactose. The presence of lactose in the surrounding environment triggers the ...

Seth Herzon Group - Professor Product Portal

Professor Product Portal Index Professor Seth Herzon The Herzon group has developed highly active catalysts for the anti-Markovnikov hydration and reductive hydration of terminal alkynes to form aldehydes and linear alcohols, respectively. The reductive hydration reaction proceeds by formation of an...

Folic Acid Metabolism: A Role in Cancer's Cause and Cure | BioFiles Volume 5 Number 6 - Cancer

BioFiles Volume 5, Number 6 — Cancer Download BioFiles v5 n6 (3.38 Mb PDF) Table of Contents • Introduction • New Cancer Biomarker Breast Cancer Malignant Melanoma Epithelial Ovarian Cancer Colon Cancer Summary • Cancer Research: Epigentic Mechanisms • Folic Acid Metabolism: A Role in Cancer's Cause...

transformation/transcription domain-associated protein
Synonyms PAF350/400, PAF400, STAF40, TR-AP, Tra1
Species Human (8295) , Species Mouse (100683) , Species Rat (288471) , Species Zebrafish (557263) , Species Horse (100059214) , Species domestic cat (101083988) , Species dog (479747) , Species chicken (416440) , Species cow (507169) , Species sheep (101103618) , Species domestic guinea pig (100723821) , Species naked mole-rat (101722141)
Summary: This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Building and Engineering Micro/Nano Architectures of Single-Walled Carbon Nanotubes for Electronic Applications

1Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA 2Department of Physics, Northeastern University, Boston, MA 02115, USA 3Department of Mechanical Engineering, Villanova University, Villanova, PA 19085, USA *Email: y.jung@northeastern.edu Single-wal...

cataCXium® - Ligands and Complexes for Efficient Cross-Coupling Reactions

. Introduction . Advantages . Representative Application . Materials List Cross-coupling reactions are an important class of catalytic transformations with applications in polymer science as well as in the fine chemicals and pharmaceutical industries. The use of aryl chlorides for these transformati...

Selective 1,2-Additions with LaCl3·2LiCl

While the 1,2-addition of Grignard reagents to ketones is undoubtedly a powerful transformation, oftentimes selectivity issues arising from competitive alpha-deprotonation detract from the use of these reagents. Various methods have been developed to address this shortcoming, including the use of Ce...

Burdock (Arctium lappa) | Plant Profiler

Synonyms / Common Names / Related Terms Akujitsu, anthraxivore, arctii, arctiin, arctigenin, arctiol, Arctium lappa Linne, Arctium minus, Arctium tomentosa, Arctium tomentosum Mill., Asteraceae (family), bardana, Bardanae Radix, bardane, bardane grande (French), beggar's buttons, burdock root, burr,...

Preparation of Competent Cells and Transformation with pGEX DNA

In these procedures, E. coli host cells are made competent and then transformed with either uncut pGEX DNA or recombinant pGEX DNA. If electroporation is used to transform the cells, see Appendix 3 (Electroporation). Otherwise, proceed as described below. Transform 1 ng of uncut (supercoiled) vector...

Formation of Complex Boronic Acids from MIDA Boronates

Another extremely useful feature of the MIDA boronates is their compatibility with a wide range of common synthetic reagents, allowing for the elaboration of functionalized MIDA boronates to create structurally complex boronic acid surrogates. This was recently demonstrated by Burke and coworkers wi...

TRC Library Citations

Publish Sooner When You Partner with the MISSION® shRNA Team! The MISSION® TRC1.5 human and mouse shRNA libraries are the proven performers for small-scale to high-throughput RNAi screening. Below you will find a selection of papers where researchers have published in peer-reviewed journals using th...

Barry Sharpless Group – Professor Product Portal

Related Links • VIEW PRODUCT LIST • Professor Product Portal • Catalysis and Inorganic Chemistry • Chemical Biology Professor Product Portal Index Professor Barry Sharpless The Sharpless Lab pursues useful new reactivity and general methods for selectively controlling chemical reactions. Though the ...

Protein Tyrosine Kinase and Phosphatase Expression Profiling - Cancer Research

Cancer Research PTK/PTP Expression Profiling By focusing on analysis techniques and protocols specific for Cancer Research, Sigma-Aldrich® is putting your research needs first. We will be featuring different cancer research tools throughout the year, providing you with the latest techniques and prod...

Trending Papers

February 2017 Chimera animals have been created to both study drug effects in humans and also the goal of creating organs for use in humans. A recent breakthrough using CRISPR has occurred to knockout an animal fetus’ immune response to human cells. Now that the human cells can flourish in a non-hum...

Insulin-like Growth Factors (IGF)

BioFiles 2009, 4.5, 12. Insulin-like growth factors (IGF-I and IGF-II) are mitogenic and anabolic peptides structurally homologous to insulin. IGF-I and -II are single polypeptide chains of approximately 7.5 kDa comprised of 70 and 67 amino acid residues, respectively. IGF-I and -II share 70% homolo...

Organic Dyes for Efficient and Stable Dye-Sensitized Solar Cells

• • Download PDF • Kohjiro Hara Nagatoshi Koumura Kohjiro Hara1 and Nagatoshi Koumura2 National Institute of Advanced Industrial Science and Technology (AIST), 1Research Center for Photovoltaics and 2Photonics Research Institute 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan Email: k-hara@aist.go.j...

J. Hu Group – Professor Product Portal

Related Links • VIEW PRODUCT LIST • Professor Product Portal • Catalysis and Inorganic Chemistry • Organic Synthetic Chemistry Professor Product Portal Index Professor Jinbo Hu The major research interests of Prof. Jinbo Hu's lab include the development of new fluorination reagents and reactions, es...

MRT - Ring Closure — Synthesis of Methylenecyclopentane

Aldrich ChemFiles 2009, 9.4, 14. Benefit from MRT & Flow Chemistry: complete suppression of sidereactions. The cyclization of 1,5-hexadiene to exo-methylenecyclopentane (251356) poses multiple challenges: the batch reaction affords an inseperable mixture of the endo- and exo-cyclization product (Sch...

MAPKs

The mitogen-activated protein kinase (MAPK) family consists of both stress activated (SAPK) and mitogen-activated (MAPK) protein kinases. They form a network of signal transduction cascades that mediate cellular responses to a diverse range of stimuli, including growth factors, chemical or osmotic s...

Lipshutz Designer Surfactants FAQs

Lipshutz Group - Professor Product Portal Page Professor Product Portal Index Micellar catalysis has made many of the most synthetically useful transformations possible under aqueous conditions, vastly reducing the impact of organic solvent on reaction waste streams. This technology is enabled by th...

Dudley Reagents: Benzyl and p-Methoxy Benzyl Protections Using Benzyloxypyridinium Triflate and 2-(4-Methoxybenzyloxy)-4-methylquinoline

Benzyl and p-methoxy benzyl protecting groups are ubiquitous in organic synthesis. However, employment of these protecting groups commonly requires use of acidic or basic reaction media and or otherwise non-mild reaction conditions, which sometimes are not compatible with other functional groups in ...

High Pure Technology and Silica Adsorption Kits

The High Pure and silica adsorption kits developed by Roche depend on the tendency of nucleic acids to adsorb to silica (glass) in the presence of a chaotropic salt such as sodium iodide (NaI), guanidine thiocyanate or guanidine hydrochloride [Melzak et al. (1996), J. Colloid Interface Sci. (USA) 18...

Inkjet Printing as a Key Enabling Technology for Printed Electronics

Related eTool • OLED eFabricator • • Download PDF • 1 Department Printed Functionalities, Fraunhofer Research Institute for Electronic Nano Systems (ENAS), Technologie-Campus 3, 09126 Chemnitz, Germany 2 Institute for Print and Media Technology, Department of Mechanical Engineering, Chemnitz Univers...

MIDA-protected Boronate Esters

• • Download PDF • Product Manager The Suzuki-Miyaura cross-coupling reaction is one of the most important and highly utilized reactions in organic chemistry, with applications in polymer science as well as in the fine chemicals and pharmaceutical industries. However, some classes of boronic acids a...

A general protocol for the generation of Nanobodies for structural biology

Nature Protocols Volume 9 Issue 3, 27 March 2014, Pages 674 - 693 doi: 10.1038/nprot.2014.039 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. Els Pardon a, b , Toon Laeremans a, b , Sarah Triest a, b , Søren G F Rasmussen c , Alexandre Wohlkönig a, b , Armin...