New Products for Chemical Synthesis

PSI Reagents from the Baran Laboratory: The Baran Lab. The new PSI Reagents were developed for stereocontrolled synthesis of phosphorothioate oligonucleotides. These reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in their preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs). These reagents come in enantiomeric (+)-PSI and (-)-PSI form.

Jamison Nickel Precatalysts: Nickel catalysis has broad synthetic utility, though their use has been hindered by things like high catalyst loading and scarce bench stable sources. The Jamison Group has combated these issues in the development of several air- and water-stable nickel precatalysts that can be used under ambient conditions.

Synthetic Reagents

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902780 Carbon disulfide solution 5.0 M in hexane New
902624 Diethyl 2-((tosyloxy)imino)malonate ≥95% New
902764 Diisopropyl 2,2-dihydroxymalonate ≥95% New
902705 Diisopropyl 2-(((methylsulfonyl)oxy)imino)malonate ≥95% New
902594 Diisopropyl 2-oxomalonate ≥95% New
902748 Dimethyl 2-((tosyloxy)imino)malonate ≥95% New
900258 Isopropoxy(phenyl)silane New
902640 (S)-4-Methyl-2-oxazolidinone New
ALD00602 (–)-PSI Reagent ≥95% New
ALD00604 (+)-PSI Reagent 95% New
901362 N-Sulfinyltritylamine New

Chemical Biology

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QBD11305 Amino-dPEG ®24-amido-dPEG ®24-acid New
901979 N-Azidoacetylglucosamine-tetraacylated New
QBD10526 Azido-dPEG ®35-amine >90% New
QBD10567 Azido-dPEG ®4-TFP ester New
QBD10569 Azido-dPEG ®12-TFP ester >90% New
QBD10571 Azido-dPEG ®24-TFP ester New
QBD10573 Azido-dPEG ®36-TFP ester New
QBD11386 Biotin-dPEG ®4 amido-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11811 Biotin-dPEG ®12-DBCO New
QBD11338 Bis-Bromoacetamido-dPEG ®11 New
QBD11372 Bis-dPEG ®11-DBCO New
QBD10215 Bis-MAL-dPEG®3 New
QBD10397 Bis-MAL-dPEG®11 New
QBD11221 Bromoacetamido-dPEG ®4-amido-DBCO New
QBD11223 Bromoacetamido-dPEG ®12-amido-DBCO New
QBD11224 Bromoacetamido-dPEG ®24-amido-DBCO New
QBD11217 Bromoacetamido-dPEG ®3-azide New
QBD11204 Bromoacetamido-dPEG ®11-azide New
QBD11205 Bromoacetamido-dPEG ®23-azide New
QBD11200 Bromoacetamido-dPEG ®4-TFP ester New
QBD11202 Bromoacetamido-dPEG ®12-TFP ester New
QBD11203 Bromoacetamido-dPEG ®24-TFP ester New
QBD11385 Carboxyfluorescein-dPEG ®24-amido-dPEG ®24-DSPE New
QBD10885 Carboxyfluorescein-dPEG ®12-NHS ester New
902314 [CpRu(Fmoc-tyrosin)]CF3CO2 New
QBD11383 DBCO-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11812 DBCO-dPEG ®12-carboxyfluorescein New
QBD10593 DBCO-dPEG ®12-MAL New
QBD10594 DBCO-dPEG ®24-MAL New
QBD11362 DBCO-dPEG ®4-TFP ester New
QBD11366 DBCO-dPEG ®12-TFP ester New
QBD11370 DBCO-dPEG ®24-TFP ester New
QBD11815 DBCO-TFP ester New
901765 Dde biotin-azide New
QBD11384 DOTA-tris(acid)-amido-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11150 DOTA-tris(acid)-amido-dPEG ®3-bromoacetamide New
QBD11152 DOTA-tris(acid)-amido-dPEG ®11-bromoacetamide New
QBD11167 DOTA-tris(acid)-amido-dPEG ®11-Maleimide New
QBD11171 DOTA-tris(acid)-amido-dPEG ®23-Maleimide New
QBD11160 DOTA-tris(acid)-amido-dPEG ®4-TFP ester New
QBD11162 DOTA-tris(acid)-amido-dPEG ®12-TFP ester New
QBD11163 DOTA-tris(acid)-amido-dPEG ®24-TFP ester New
QBD11166 DOTA-tris(TBE)-amido dPEG ®11-Maleimide New
QBD11170 DOTA tris(TBE)-amido-dPEG ®23-Maleimide New
QBD11155 DOTA-tris(TBE)-amido-dPEG ®4-TFP ester New
QBD11157 DOTA-tris(TBE)-amido-dPEG ®12-TFP ester New
QBD11158 DOTA-tris(TBE)-amido-dPEG ®24-TFP ester New
QBD11095 m-dPEG ®25-amido-dPEG ®24-DSPE New
QBD10540 m-dPEG ®24-Azide (Azido-m-dPEG ®24) New
QBD10596 m-dPEG ®12-DBCO New
QBD11086 m-dPEG ®13-NHS ester New
QBD11087 m-dPEG ®13-TFP ester New
QBD10994 Fmoc-N-amido-dPEG ®4-NHS ester New
QBD10995 Fmoc-N-amido-dPEG ®8-NHS ester New
QBD10996 Fmoc-N-amido-dPEG ®12-NHS ester New
QBD11000 Fmoc-N-amido-dPEG ®4-TFP ester New
QBD11005 Fmoc-N-amido-dPEG ®8-TFP ester New
QBD11006 Fmoc-N-amido-dPEG ®12-TFP ester New
QBD11007 Fmoc-N-amido-dPEG ®24-TFP ester New
QBD11008 Fmoc-N-amido-dPEG ®36-TFP ester New
QBD11436 Hexa(-amido-dPEG ®11-MAL)dipentaerythritol New
QBD11341 Hydroxy-dPEG ®4-TFP ester New
QBD11345 Hydroxy-dPEG ®12-TFP ester New
QBD11349 Hydroxy-dPEG ®24-TFP ester New
902586 Hydroxy-PEG4-t-butyl ester New
902578 Hydroxy-PEG6-t-butyl ester ≥95% New
902756 Imidazole-1-sulfonyl azide, HCl salt New
QBD11388 Mal-dPEG ®24-amido-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11093 MAL-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11303 MAL-dPEG ®24-amido-dPEG ®24-TFP ester New
QBD11028 MAL-dPEG ®12-DSPE New
QBD10555 MAL-dPEG ®36-TFP ester New
QBD11373 Methoxy-dPEG ®25-DSPE New
901981 Methyltetrazine-amine hydrochloride New
QBD11382 NHS ester-dPEG ®25-amido-dPEG ®24-DSPE New
901984 PC biotin-alkyne New
901767 PC biotin-PEG3-NHS ester New
901835 Pomalidomide-PEG6-Alkyne New
903434 Pomalidomide-PEG6-butyl azide ≥95% New
903442 Pomalidomide-PEG6-butyl iodide ≥95% New
901824 Pomalidomide-PEG4-CO2H New
902667 Propargyl-PEG6-acid New
QBD11435 Tetra(-amido-dPEG ®11-MAL)pentaerythritol New
QBD11414 Tetra(-amido-dPEG ®23-MAL)pentaerythritol New
QBD11371 Tetra(-dPEG ®11-DBCO)PE New
QBD11029 TFP-dPEG ®13-DSPE New

Catalysis

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902985 (Bathocuproine)NiBr2 New
903000 [4,4′-Bis(1,1-dimethylethyl)-2,2′-bipyridine] nickel (II) dichloride New
902810 4,4′-Bis(trifluoromethyl)-2,⋅2′-bipyridine New
901741 Bis(triphenyl-λ5-phosphanylidene)ammonium hydrogendifluoride New
902993 (BPhen)Ni(OAc)2.xH2O New
903701 tBuDavePhos Pd G3 1:1 THF adduct New
903663 t-BuDavePhos Pd G4 New
901904 tBuXPhos 95% New
904104 CoCl2(PCy3)2 New
903728 DavePhos Pd G2 New
903019 [4,4′-Dimethyl-2,2′-bipyridine]nickel(II) dichloride hydrate ≥95% New
904694 Ir(p-CF3-ppy)3 ≥95% New
903167 10-Phenylphenothiazine ≥95% New
901906 SPhos 95% New
Z742608 Photo KitAlysis 24-Green LED Array New
Z742612 Photo KitAlysis Starter Kit New
Z742609 Photo KitAlysis 24-White LED Array New
903027 QPhos Pd G3 New
901907 RuPhos 95% New
901760 StickyCat PF6 ≥95% New
Z742680 SynLED Parallel Photoreactor New
KITALYSIS-PHO KitAlysis High-Throughput 24-Catalyst Photoredox Reaction Screening Kit-Pack of 2 New
901814 UltraCat ≥95% New

Building Blocks

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901779 4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile New
901719 Benzyl (S)-2-(5-bromo-1H-indole-3-carbonyl)pyrrolidine-1-carboxylate New
901735 1-Benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate New
901733 (R)-2-(5-Bromo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid New
901745 5-Bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide ≥90% New
901744 2-(5-(3-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid New
901724 3-((5-Bromopyridin-2-yl)oxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one New
901782 tert-Butyl (R)-3-(2-acetamidopropan-2-yl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4′-piperidine]-1′-carboxylate New
901752 N-(tert-Butyl)-4′-((6-iodo-4-oxo-2-propylquinazolin-3(4H)-yl)methyl)-[1,1′-biphenyl]-2-sulfonamide New
901753 (S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one New
901729 Ethyl 4-(3-bromo-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate New
901778 Ethyl 8-bromo-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate New
902713 1-Hydroxy-2(1H)-pyridinethione ≥95% New
901723 Methyl 2-(9-bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[1,2,3-de]quinoxalin-5-yl)acetate ≥90% New