New Products for Chemical Synthesis

Our most effective photoreactor yet: The SynLED Parallel Photoreactor performs reaction optimization and rapid library generation. The new photoreactor allows for simple small-scale photocatalysis reactions and was specifically designed to ensure high levels of consistency across reactions and between runs. Features include:
  • 4x4 array allowing up to 16 reactions in parallel (1-2-gram vials)
  • Bottom-lit blue LEDs (465-470 nm) provide consistent light intensity
  • Built-in cooling fan provides consistent temperature across reactions

New molecules in targeted protein degradation: To accelerate PROTACs research, we have introduced new E3 ligase ligands and Partial PROTACs, which are E3 ligase ligand-linker conjugates that simplify PROTAC synthesis and library generation. These new Partial PROTACs provide the following advantages:
  • Chemical compatibility: Linkers conjugate to common functional groups present on lead molecules, such as amines, carboxylic acids, and azides via click chemistry.
  • Molecule design: Strategic variation in the permutations of linker length, linker composition, and E3 ligands aids design and accelerates discovery of optimal target degraders.
  • Synthetic time-saver: Partial PROTACs decrease the amount of time spent on PROTACs synthesis.
  • Library generation: Using Partial PROTACs with the same conjugation site streamlines the generation of several PROTAC derivatives via parallel chemical synthesis.

Synthetic Reagents

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901821 Benzene-1,3,5-triyl triformate New
901251 [2,2′-Bipyridine]-6-carboxylic acid hydrochloride New
901606 tert-Butyl carbazate solution 1.0 M in dichloromethane New
901415 N-(tert-Butyl)-N-((ethoxycarbonothioyl)thio)-3,5-bis(trifluoromethyl)benzamide New
901599 Carbon disulfide solution 5 M in ethanol New
902780 Carbon disulfide solution 5.0 M in hexane New
902144 [(Cp)Ru(η6-naphthalene)]OTf ≥95% New
902772 (Diacetoxyiodo)benzene solution 0.50 M solution in DCM New
900624 Di-t-butyl oxaziridine ≥95% New
901586 2-Ketobutyric acid solution 1.0 M in toluene New
KITALYSIS-BOR KitAlysis High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2 New
902039 4-Methoxypicolinimidamide hydrochloride ≥95% New
902640 (S)-4-Methyl-2-oxazolidinone New
902063 (2Z,6Z)-N′2,N′6-Dicyanopyridine-2,6-bis(carboximidamide) New
ALD00602 (–)-PSI Reagent ≥95% New
ALD00604 (+)-PSI Reagent 95% New
902047 Pyridine-2,6-bis(carboximidamide) dihydrochloride ≥95% New
901250 2-(Pyridin-2-yl)quinolin-8-amine dihydrochloride New
901813 SnatchCat ≥95% New
902136 2,4,6-Tri-(4-fluorophenyl)pyrylium tetrafluoroborate ≥95% New
902489 Tris(trimethylsilyl)silanol ≥95% New
901595   Vinylene carbonate solution 1.0 M in ethyl acetate New

Chemical Biology

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901490 (S,R,S)-AHPC hydrochloride ≥97% New
901487 (S,S,S)-AHPC hydrochloride ≥97% New
901503 (S,R,S)-AHPC-PEG1-Alkyne ≥95% New
901517 (S,R,S)-AHPC-PEG2-Alkyne ≥95% New
901533 (S,R,S)-AHPC-PEG3-Alkyne ≥95% New
901511 (S,R,S)-AHPC-PEG3-NH2 hydrochloride ≥95% New
901488 (S,R,S)-AHPC-PEG2-NH2 hydrochloride ≥95% New
901982 Alkyne Agarose New
QBD11305 Amino-dPEG ®24-amido-dPEG ®24-acid New
QBD10526 Azido-dPEG ®35-amine >90% New
QBD10567 Azido-dPEG ®4-TFP ester New
QBD10569 Azido-dPEG ®12-TFP ester >90% New
QBD10571 Azido-dPEG ®24-TFP ester New
QBD10573 Azido-dPEG ®36-TFP ester New
QBD11386 Biotin-dPEG ®4 amido-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11811 Biotin-dPEG ®12-DBCO New
QBD11338 Bis-Bromoacetamido-dPEG ®11 New
QBD11372 Bis-dPEG ®11-DBCO New
QBD10215 Bis-MAL-dPEG®3 New
QBD10397 Bis-MAL-dPEG®11 New
QBD11221 Bromoacetamido-dPEG ®4-amido-DBCO New
QBD11223 Bromoacetamido-dPEG ®12-amido-DBCO New
QBD11224 Bromoacetamido-dPEG ®24-amido-DBCO New
QBD11217 Bromoacetamido-dPEG ®3-azide New
QBD11204 Bromoacetamido-dPEG ®11-azide New
QBD11205 Bromoacetamido-dPEG ®23-azide New
QBD11200 Bromoacetamido-dPEG ®4-TFP ester New
QBD11202 Bromoacetamido-dPEG ®12-TFP ester New
QBD11203 Bromoacetamido-dPEG ®24-TFP ester New
QBD11385 Carboxyfluorescein-dPEG ®24-amido-dPEG ®24-DSPE New
QBD10885 Carboxyfluorescein-dPEG ®12-NHS ester New
QBD11383 DBCO-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11812 DBCO-dPEG ®12-carboxyfluorescein New
QBD10593 DBCO-dPEG ®12-MAL New
QBD10594 DBCO-dPEG ®24-MAL New
QBD11362 DBCO-dPEG ®4-TFP ester New
QBD11366 DBCO-dPEG ®12-TFP ester New
QBD11370 DBCO-dPEG ®24-TFP ester New
QBD11815 DBCO-TFP ester New
901995 Diazo biotin-alkyne ≥90% New
QBD11384 DOTA-tris(acid)-amido-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11150 DOTA-tris(acid)-amido-dPEG ®3-bromoacetamide New
QBD11152 DOTA-tris(acid)-amido-dPEG ®11-bromoacetamide New
QBD11167 DOTA-tris(acid)-amido-dPEG ®11-Maleimide New
QBD11171 DOTA-tris(acid)-amido-dPEG ®23-Maleimide New
QBD11160 DOTA-tris(acid)-amido-dPEG ®4-TFP ester New
QBD11162 DOTA-tris(acid)-amido-dPEG ®12-TFP ester New
QBD11163 DOTA-tris(acid)-amido-dPEG ®24-TFP ester New
QBD11166 DOTA-tris(TBE)-amido dPEG ®11-Maleimide New
QBD11170 DOTA tris(TBE)-amido-dPEG ®23-Maleimide New
QBD11155 DOTA-tris(TBE)-amido-dPEG ®4-TFP ester New
QBD11157 DOTA-tris(TBE)-amido-dPEG ®12-TFP ester New
QBD11158 DOTA-tris(TBE)-amido-dPEG ®24-TFP ester New
QBD11095 m-dPEG ®25-amido-dPEG ®24-DSPE New
QBD10540 m-dPEG ®24-Azide (Azido-m-dPEG ®24) New
QBD10596 m-dPEG ®12-DBCO New
QBD11086 m-dPEG ®13-NHS ester New
QBD11087 m-dPEG ®13-TFP ester New
QBD10994 Fmoc-N-amido-dPEG ®4-NHS ester New
QBD10995 Fmoc-N-amido-dPEG ®8-NHS ester New
QBD10996 Fmoc-N-amido-dPEG ®12-NHS ester New
QBD11000 Fmoc-N-amido-dPEG ®4-TFP ester New
QBD11005 Fmoc-N-amido-dPEG ®8-TFP ester New
QBD11006 Fmoc-N-amido-dPEG ®12-TFP ester New
QBD11007 Fmoc-N-amido-dPEG ®24-TFP ester New
QBD11008 Fmoc-N-amido-dPEG ®36-TFP ester New
QBD11436 Hexa(-amido-dPEG ®11-MAL)dipentaerythritol New
QBD11341 Hydroxy-dPEG ®4-TFP ester New
QBD11345 Hydroxy-dPEG ®12-TFP ester New
QBD11349 Hydroxy-dPEG ®24-TFP ester New
QBD11388 Mal-dPEG ®24-amido-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11093 MAL-dPEG ®24-amido-dPEG ®24-DSPE New
QBD11303 MAL-dPEG ®24-amido-dPEG ®24-TFP ester New
QBD11028 MAL-dPEG ®12-DSPE New
QBD10555 MAL-dPEG ®36-TFP ester New
QBD11373 Methoxy-dPEG ®25-DSPE New
901494 N-Methylated pomalidomide ≥98% New
901981 Methyltetrazine-amine hydrochloride New
QBD11382 NHS ester-dPEG ®25-amido-dPEG ®24-DSPE New
901984 PC biotin-alkyne New
901763 PC biotin-azide New
901767 PC biotin-PEG3-NHS ester New
901500 Pomalidomide-C3-CO2H ≥95% New
901525 Pomalidomide-C9-CO2H ≥95% New
901523 Pomalidomide-PEG1-Alkyne ≥98% New
901529 Pomalidomide-PEG2-Alkyne ≥95% New
901835 Pomalidomide-PEG6-Alkyne New
901526 Pomalidomide-PEG2-CO2H ≥98% New
901504 Pomalidomide-PEG3-CO2H ≥95% New
901824 Pomalidomide-PEG4-CO2H New
901828 Pomalidomide-PEG5-CO2H ≥98% New
901516 Pomalidomide-PEG1-NH2 hydrochloride ≥95% New
901513 Pomalidomide-PEG2-NH2 hydrochloride ≥95% New
901495 Pomalidomide-PEG3-NH2 hydrochloride ≥95% New
QBD11435 Tetra(-amido-dPEG ®11-MAL)pentaerythritol New
QBD11414 Tetra(-amido-dPEG ®23-MAL)pentaerythritol New
QBD11371 Tetra(-dPEG ®11-DBCO)PE New
901990 Tetrazine-acid New
901989 Tetrazine-NHS ester New
QBD11029 TFP-dPEG ®13-DSPE New

Catalysis

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901759 AquaMet New
900811 (S)-2-(2,3-Bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride ≥95% New
902810 4,4′-Bis(trifluoromethyl)-2,⋅2′-bipyridine New
902829 2-(2,4-Difluorophenyl)-5-methylpyridine ≥95% New
901808 GreenCat iPr ≥95% New
902217 Ir[dFFppy]2-(4,4′-dCF3bpy)PF6 ≥95% New
902225 Ir[dFMeppy]2-(4,4′-dCF3bpy)PF6 ≥95% New
KITALYSISBASE KitAlysis High-Throughput Base Screening Kit - Pack of 2 New
901755 nitro-Grela ≥95% New
901787 nitro-Grela-I2 ≥95% New
901784 Nitro-grela 1st generation ≥95% New
901786 nitro-Grela SI-o-tolyl ≥95% New
Z742680 SynLED Parallel Photoreactor New
902000 UltraNitroCat ≥95% New

Building Blocks

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901719 Benzyl (S)-2-(5-bromo-1H-indole-3-carbonyl)pyrrolidine-1-carboxylate New
901733 (R)-2-(5-Bromo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid New
901745 5-Bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide ≥90% New
901744 2-(5-(3-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid New
901724 3-((5-Bromopyridin-2-yl)oxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one New
901782 tert-Butyl (R)-3-(2-acetamidopropan-2-yl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4′-piperidine]-1′-carboxylate New
901753 (S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one New
900976 2-(4-Chloro-3-iodo-7-methyl-1H-pyrrolo[3,2-c]pyridin-1-yl)ethan-1-amine dihydrochloride ≥95% New
900974 2-(4-Chloro-3-iodo-1H-pyrrolo[3,2-c]pyridin-1-yl)ethan-1-amine dihydrochloride ≥95% New
901729 Ethyl 4-(3-bromo-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate New
901723 Methyl 2-(9-bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[1,2,3-de]quinoxalin-5-yl)acetate ≥90% New
902861 Methyl 4-bromo-1-methyl-1H-pyrrole-2-carboxylate New