Amino Acid Azides/Alkynes

Peptide synthesis using natural and non-natural amino acids is a powerful tool in the development of therapeutics and understanding biological chemistry. Sigma-Aldrich offers a variety of Fmoc and Boc protected azido amino acids for your peptide or amino acid based chemical ligation needs, such as azide-alkyne or Huisgen cycloaddition reactions and Staudinger ligations.

Product #



Molecular Formula

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909823 3-Azido-D-alanine hydrochloride ≥95% New C3H6N4O2 · HCl
714291 (S)-5-Azido-2-(Fmoc-amino)pentanoic acid ≥97.0% (HPLC) C20H20N4O4
900892 L-Azidohomoalanine hydrochloride C4H8N4O2 · HCl
714259 (S)-2 Azido-3-(3-indolyl)propionic acid cyclohexylammonium salt ≥98% (HPLC) C11H10N4O2 · C6H13N
909564 4-Azido-L-phenylalanine ≥98% New C9H10N4O2
690767 (S)-2-Azido-3-phenylpropionic acid (dicyclohexylammonium) salt ≥98% C9H9N3O2 · C12H23N
714232 (R)-2-(Boc-amino)-5-hexynoic acid ≥96% (HPLC) C11H17NO4
712221 Boc-propargyl-Gly-OH ≥98.0% (HPLC) C10H15NO4
711977 Boc-(R)-4-(2-propynyl)-L-proline ≥96% C13H19NO4
690430 (S)-(−)-4-tert-Butyl hydrogen 2-azidosuccinate (dicyclohexylammonium) salt ≥98.0% C8H13N3O4 · C12H23N
774995 N2-[(1,1-Dimethylethoxy)carbonyl]-N6-[(2-propynyloxy)carbonyl]-L-lysine 90% C15H24N2O6
714151 Fmoc-β-azido-Ala-OH ≥98.0% (HPLC) C18H16N4O4
F5312 Fmoc-(R)-propargyl-Ala-OH C21H19NO4
F5437 Fmoc-(S)-propargyl-Ala-OH C21H19NO4