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Standard Fmoc Amino Acids

Fmoc based solid phase peptide synthesis (SPPS) is a preferred coupling strategy for many researchers due to the versatility, ease of use, and mild deprotection conditions. The importance of peptides in basic research and medicine make SPPS an essential technique for building the necessary tools for studying anything from peptide structure and folding, to complex peptide/protein-biomolecule interactions. Sigma-Aldrich is happy to provide all the basic building blocks you need for Fmoc based SPPS.

Learn more about the benefits of Purer Fmocs in Peptide Synthesis here.

Product #



Molecular Formula

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531480 Fmoc-Ala-OH 95% C18H17NO4
47349 Fmoc-Arg(Pbf)-OH ≥98.0% (HPLC) C34H40N4O7S
47672 Fmoc-Asn(Trt)-OH ≥97.0% C38H32N2O5
47618 Fmoc-Asp(OtBu)-OH ≥98.0% (HPLC) C23H25NO6
47695 Fmoc-Cys(Trt)-OH ≥95.0% (sum of enantiomers, HPLC) C37H31NO4S
47674 Fmoc-Gln(Trt)-OH ≥98.0% (HPLC) C39H34N2O5
47625 Fmoc-Glu(OtBu)-OH ≥98.0% (HPLC) C24H27NO6
47627 Fmoc-Gly-OH ≥98.0% (T) C17H15NO4
47639 Fmoc-His(Trt)-OH ≥98.0% (sum of enantiomers, HPLC) C40H33N3O4
47628 Fmoc-Ile-OH ≥98.0% (T) C21H23NO4
47633 Fmoc-Leu-OH ≥97.0% C21H23NO4
47624 Fmoc-Lys(Boc)-OH ≥98.0% (HPLC) C26H32N2O6
47634 Fmoc-Met-OH ≥98.0% (HPLC) C20H21NO4S
338338 Fmoc-Phe-OH 98% C24H21NO4
47636 Fmoc-Pro-OH ≥99.0% (HPLC) C20H19NO4
47619 Fmoc-Ser(tBu)-OH ≥98.0% (HPLC) C22H25NO5
47622 Fmoc-Thr(tBu)-OH ≥98.0% (HPLC) C23H27NO5
47561 Fmoc-Trp(Boc)-OH ≥97.0% (HPLC) C31H30N2O6
47623 Fmoc-Tyr(tBu)-OH ≥98.0% (HPLC) C28H29NO5
47638 Fmoc-Val-OH ≥98.0% (HPLC) C20H21NO4