Nucleobase, Nucleoside and Nucleotide Derivatives

Various nucleoside analogs have found use in basic research and as drug and drug candidates such as the antivirals Acyclovir and azidothymidine (AZT). Sigma-Aldrich offers a variety of key building blocks and intermediates for use in the development of nucleoside and nucleotide analogs and oligonucleotide synthesis.

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A26209 Adenosine 5′-triphosphate disodium salt hydrate 99% C10H14N5Na2O13P3 · xH2O
496812 7-Allyl-7,8-dihydro-8-oxoguanosine 95% C13H17N5O6
858412 (−)-2-Amino-6-mercaptopurine riboside hydrate 98% C10H13N5O4S · xH2O
808539 γ-(2-Azidoethyl)-ATP sodium salt solution C12H19N8O13P3 · xNa+
808520 γ-[(6-Azidohexyl)-imido]-ATP sodium salt C16H28N9O12P3 · xNa+
586846 N-Benzoyladenosine 96% C17H17N5O5
326151 N4-Benzoylcytidine 99% C16H17N3O6
858463 8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt monohydrate 98% C10H10BrN5NaO6P · H2O
766011 8-Bromoinosine 95% C10H11BrN4O5
850187 5-Bromouridine 98% C9H11BrN2O6
766739 5′-Chloro-2′,3′-isopropylidene adenosine 97% C13H16ClN5O3
713465 6-Chloro-3-methyluracil ≥98% C5H5ClN2O2
C122106 Cytidine 99% C9H13N3O5
809705 5-DBCO-PEG4-dUTP, 10mM Aqueous Solution C42H54N5O21P3
852198 2′-Deoxyadenosine 5′-monophosphate monohydrate 98% C10H14N5O6P · H2O
854980 2′-Deoxycytidine hydrate ≥99% (HPLC) C9H13N3O4 · xH2O
T511293 (2′S)-2′-Deoxy-2′-fluoro-5-ethynyluridine, (F-ara-EdU) AldrichCPR C11H11FN2O5
361275 3′-Deoxy-3′-fluorothymidine 97% C10H13FN2O4
854999 2′-Deoxyguanosine hydrate 99% C10H13N5O4 · xH2O
852228 2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate ≥98% C10H12N5Na2O7P · xH2O
766755 2,6-Diaminopurine-9-arabinoside 97% C10H14N6O4
T511307 5-Ethynyl-2′-deoxycytidine, (EdC) AldrichCPR C11H13N3O4
656402 2-Fluoroadenosine 97% C10H12FN5O4
543020 5-Fluorocytidine 97% C9H12FN3O5
656399 2-Fluoro-2′-deoxyadenosine 96% C10H12FN5O3
663115 2-Iodoadenosine 97% C10H12IN5O4
I22404 2′,3′-O-Isopropylideneadenosine 98% C13H17N5O4
M2780 N6-Methyladenosine 5′-monophosphate sodium salt ≥97% (HPLC) C11H15N5NaO7P
535893 5-Methyluridine 97% C10H14N2O6
808490 N6-Propargyl-ATP sodium salt C13H18N5O13P3 · xNa+
808512 γ-[(Propargyl)-imido]-ATP sodium salt C13H19N6O12P3 · xNa+
850926 2′,3′,5′-Tri-O-acetylguanosine 98% C16H19N5O8