Benzimidazoles

Benzimidazole, a heterocyclic aromatic organic compound consisting of a fusion of benzene and imidazole, in an extension of the well-elaborated imidazole system, has been used as a carbon skeleton for N-heterocyclic carbenes, usually used as ligand for transition metal complexes. Pharmacological compounds of benzimidazole derivatives are potent inhibitors for a variety of enzymes. Benzimidazole is a privileged scaffold, having a variety of therapeutic uses including antitumor, antifungal, antiparasitic, analgesics, antiviral, antihistamine, as well as use in cardiovascular disease, neurology, endocrinology, and ophthalmology.

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Direct Arylation of Heterocycles

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732273 6-Bromo-4-azabenzimidazole 95% C6H4BrN3
A93607 4-Azabenzimidazole 99% C6H5N3
561835 5-Azabenzimidazole 97% C6H5N3
703826 2-Bromo-1H-benzimidazole 97% C7H5BrN2
702188 6-Bromo-1H-benzimidazole 97% C7H5BrN2
CDS007377 5-bromo-1,3-dihydrobenzoimidazol-2-one AldrichCPR C7H5BrN2O
592277 2-Chlorobenzimidazole 98% C7H5ClN2
631248 5-Chlorobenzimidazole 96% C7H5ClN2
ANV00150 5,6-Dichloro-1H-benzimidazole hydrochloride (1:1) AldrichCPR C7H5Cl3N2
CDS008386 5-Fluoro-1H-benzimidazole AldrichCPR C7H5FN2
385700 2-Mercapto-5-benzimidazolesulfonic acid sodium salt dihydrate 98% C7H5N2NaO3S2 · 2H2O
263575 2-Mercapto-5-nitrobenzimidazole 97% C7H5N3O2S
558478 5-Nitro-2-benzimidazolinone 97% C7H5N3O3
194123 Benzimidazole 98% C7H6N2
CDS008334 1H-Benzoimidazol-4-ol AldrichCPR C7H6N2O
H19859 2-Hydroxybenzimidazole 97% C7H6N2O
530646 1H-Benzimidazole-2-sulfonic acid 98% C7H6N2O3S
M3205 2-Mercaptobenzimidazole 98% C7H6N2S
761575 1-Aminobenzimidazole 97% C7H7N3
171778 2-Aminobenzimidazole 97% C7H7N3
CDS003539 5-aminobenzimidazole AldrichCPR C7H7N3
725005 6-Aminobenzimidazole 95% C7H7N3
CDS003171 5-Amino-1,3-dihydro-2H-benzimidazol-2-one AldrichCPR C7H7N3O
536067 5-Amino-2-mercaptobenzimidazole 96% C7H7N3S
CBR00196 5,6-Diamino-1,3-dihydro-2H-benzimidazol-2-one AldrichCPR C7H8N4O
366307 cis-Octahydro-2H-benzimidazol-2-one 99% C7H12N2O
CDS012796 4-chloro-6-(trifluoromethyl)benzimidazole AldrichCPR C8H4ClF3N2
192538 5-Chloro-2-(trichloromethyl)benzimidazole 95% C8H4Cl4N2
760544 6-Chloro-1H-benzimidazole-2-carboxylic acid monohydrate 97% C8H5ClN2O2 · H2O
JRD0289 5-Cyanobenzimidazole AldrichCPR C8H5N3
542210 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole 97% C8H6F2N2OS
579483 5-Amino-2-(trifluoromethyl)benzimidazole 96% C8H6F3N3
734985 1H-Benzimidazole-2-carboxylic acid 97% C8H6N2O2
709166 1H-Benzimidazole-2-carboxylic acid monohydrate 97% C8H6N2O2 · H2O
CDS018249 1H-benzimidazole-6-carboxylic acid AldrichCPR C8H6N2O2
296783 5-Benzimidazolecarboxylic acid 96% C8H6N2O2
CDS016500 2-mercapto-1H-benzimidazole-6-carboxylic acid AldrichCPR C8H6N2O2S
CDS000151 2-Sulfanyl-1H-benzimidazole-5-carboxylic acid AldrichCPR C8H6N2O2S
CDS008133 6-Bromo-1-methyl-1H-benzo[d]imidazole AldrichCPR C8H7BrN2
C52055 2-(Chloromethyl)benzimidazole 96% C8H7ClN2
CBR01079 (5-Chloro-1H-benzimidazol-2-yl)methanol AldrichCPR C8H7ClN2O
CDS006508 (5-Chloro-1H-benzimidazol-2-yl)methylamine dihydrochloride AldrichCPR C8H8ClN3
399353 1-Methylbenzimidazole 99% C8H8N2
M29800 2-Methylbenzimidazole 98% C8H8N2
305235 5-Methylbenzimidazole 98% C8H8N2
CDS015837 1H-benzimidazol-5-ylmethanol AldrichCPR C8H8N2O
158356 2-Benzimidazolemethanol 97% C8H8N2O
515108 5-Methoxybenzimidazole 97% C8H8N2O
382485 5-Methoxy-2-benzimidazolethiol 99% C8H8N2OS
572748 1-Methyl-1H-benzimidazole-2-thiol 95% C8H8N2S
M54600 2-(Methylthio)benzimidazole 97% C8H8N2S
CBR00787 1H-Benzimidazol-2-ylmethanethiol hydrochloride AldrichCPR C8H9ClN2S
CDS019276 1-Methyl-1H-benzimidazol-6-amine AldrichCPR C8H9N3
165638 2-(Aminomethyl)benzimidazole dihydrochloride 98% C8H9N3 · 2HCl
412546 2-Amino-1-methylbenzimidazole 95% C8H9N3
CDS005473 5-Methyl-1H-benzimidazol-2-amine AldrichCPR C8H9N3
CBR01626 5-Amino-6-methoxy-1,3-dihydro-2H-benzimidazol-2-one AldrichCPR C8H9N3O2
CDS005677 1-(Methylsulfonyl)-1H-benzimidazol-2-amine AldrichCPR C8H9N3O2S
G11802 2-Guanidinobenzimidazole 95% C8H9N5
CBR01448 (5-Amino-1H-benzimidazol-2-yl)methanol dihydrochloride AldrichCPR C8H11Cl2N3O
B5291 (2-Benzimidazolyl)acetonitrile 97% C9H7N3
CDS009803 4-(1H-Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine AldrichCPR C9H7N5O
CBR01233 2-(2-Chloro-1H-benzimidazol-1-yl)ethanol AldrichCPR C9H9ClN2O
CBR00563 2-(6-Chloro-1H-benzimidazol-2-yl)ethanol AldrichCPR C9H9ClN2O
CDS013857 2-(1H-Benzoimidazol-2-yl)-acetamide AldrichCPR C9H9N3O
378674 Carbendazim 97% C9H9N3O2
CBR01271 1-(2-Bromoethyl)-1H-benzimidazole hydrobromide AldrichCPR C9H10Br2N2
CBR00795 2-(Chloromethyl)-6-methyl-1H-benzimidazole hydrochloride AldrichCPR C9H10Cl2N2
D147206 5,6-Dimethylbenzimidazole ≥99% C9H10N2
CBR01378 (6-Methoxy-1H-benzimidazol-2-yl)methanol AldrichCPR C9H10N2O2
CDS016371 5,6-dimethoxybenzimidazole AldrichCPR C9H10N2O2
CDS013765 2-(1H-Benzoimidazol-2-yl)-ethylamine AldrichCPR C9H11N3
657875 2-(2-Aminoethyl)benzimidazole dihydrochloride 97% C9H11N3 · 2HCl
CBR01337 5,6-Dimethyl-1H-benzimidazol-7-amine hydrochloride AldrichCPR C9H12ClN3
CBR01358 1-(4-Methyl-1H-benzimidazol-2-yl)methanamine dihydrochloride AldrichCPR C9H13Cl2N3
CBR00627 1-(5-Methyl-1H-benzimidazol-2-yl)methanamine dihydrochloride AldrichCPR C9H13Cl2N3
CBR01356 4,5-Dimethyl-1H-benzimidazol-6-amine dihydrochloride AldrichCPR C9H13Cl2N3
CBR00628 1-(5-Methoxy-1H-benzimidazol-2-yl)methanamine dihydrochloride AldrichCPR C9H13Cl2N3O
CBR00673 2-(5-Amino-1H-benzimidazol-1-yl)ethanol dihydrochloride AldrichCPR C9H13Cl2N3O
CBR01129 1-Ethyl-2-hydrazino-1H-benzimidazole hydrate AldrichCPR C9H14N4O
33818 5-Hydroxythiabendazole PESTANAL®, analytical standard C10H7N3OS
CDS011656 2-[2-(Trifluoromethyl)-1H-benzimidazol-1-yl]ethanol AldrichCPR C10H9F3N2O
696129 2-Methoxycarbonylamino-1H-benzoimidazole-6-carboxylic acid 97% C10H9N3O4
CBR00074 1-(1-Methyl-1H-benzimidazol-2-yl)ethanone AldrichCPR C10H10N2O
679402 1-Isopropenyl-2-benzimidazolidinone 97% C10H10N2O
CDS001947 1,2-Dimethyl-1H-benzimidazole-5-carboxylic acid AldrichCPR C10H10N2O2
361933 2-Benzimidazolepropionic acid 97% C10H10N2O2
CDS008063 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one AldrichCPR C10H11ClN2O
CBR01208 2-(1H-Benzimidazol-1-yl)propanoic acid hydrochloride AldrichCPR C10H11ClN2O2
CBR01235 1-(5,6-Dimethyl-1H-benzimidazol-2-yl)methanamine AldrichCPR C10H13N3
CDS019763 2-Ethyl-1-methyl-1H-benzoimidazol-5-ylamine AldrichCPR C10H13N3
CDS010874 3-(1H-Benzimidazol-1-yl)propan-1-amine AldrichCPR C10H13N3
CDS002251 2-(3-Aminopropyl)-1H-benzimidazol-5-ol AldrichCPR C10H13N3O
CBR01276 1-(5-Methyl-1H-benzimidazol-2-yl)ethanamine dihydrochloride AldrichCPR C10H15Cl2N3
CBR00683 2-(1-Methyl-1H-benzimidazol-2-yl)ethanamine dihydrochloride AldrichCPR C10H15Cl2N3
CBR00619 2-(5-Methyl-1H-benzimidazol-2-yl)ethanamine dihydrochloride AldrichCPR C10H15Cl2N3
CBR01282 2-(7-Methyl-1H-benzimidazol-2-yl)ethanamine dihydrochloride AldrichCPR C10H15Cl2N3
CBR01447 2-Isopropyl-1H-benzimidazol-5-amine dihydrochloride AldrichCPR C10H15Cl2N3
CBR01135 N-Methyl-1-(5-methyl-1H-benzimidazol-2-yl)methanamine dihydrochloride AldrichCPR C10H15Cl2N3
CDS006963 1-Allyl-1H-benzimidazole-2-carbaldehyde AldrichCPR C11H10N2O
CDS001683 1-Isopropyl-1H-benzimidazole-2-carbaldehyde AldrichCPR C11H12N2O
CDS002342 (5,7-Dimethyl-1H-benzimidazol-2-yl)acetic acid AldrichCPR C11H12N2O2
CDS011654 1-carboxymethyl-2-ethylbenzimidazole AldrichCPR C11H12N2O2
CDS011061 ([1-(1H-Benzimidazol-2-yl)ethyl]thio)acetic acid AldrichCPR C11H12N2O2S
CDS005825 (4-Methyl-1H-benzoimidazol-2-ylmethoxy)-acetic acid AldrichCPR C11H12N2O3
CDS011046 [2-(Methoxymethyl)-1H-benzimidazol-1-yl]acetic acid AldrichCPR C11H12N2O3
CBR00449 3-(5-Methyl-1H-benzimidazol-2-yl)propan-1-ol AldrichCPR C11H14N2O
CBR00100 1-Isobutyl-1H-benzimidazol-2-amine AldrichCPR C11H15N3
CDS019766 2-tert-Butyl-1H-benzimidazol-5-amine AldrichCPR C11H15N3
CBR00674 2-Methyl-1-propyl-1H-benzimidazol-5-amine dihydrochloride AldrichCPR C11H17Cl2N3
CBR01275 3-(1-Methyl-1H-benzimidazol-2-yl)-1-propanamine dihydrochloride hydrate AldrichCPR C11H19Cl2N3O
CDS002081 5-(1H-Benzoimidazol-2-ylsulfanyl)-furan-2-carbaldehyde AldrichCPR C12H8N2O2S
155101 2-(2-Pyridyl)benzimidazole 97% C12H9N3
642711 2-(3-Pyridyl)-1H-benzimidazole 97% C12H9N3
CDS015707 4-[2-(trifluoromethyl)-1H-benzimidazol-1-yl]butanoic acid AldrichCPR C12H11F3N2O2
CDS016781 2-(2-ethyl-benzoimidazol-1-yl)-propionic acid AldrichCPR C12H14N2O2
CDS002201 3-(5,7-Dimethyl-1H-benzimidazol-2-yl)propanoic acid AldrichCPR C12H14N2O2
CBR00367 2-Piperidin-3-yl-1H-benzimidazole AldrichCPR C12H15N3
129550 4-(2-Keto-1-benzimidazolinyl)piperidine 98% C12H15N3O
O3132 Oxibendazole ~98% C12H15N3O3
CDS019551 1-(Piperidin-3-yl)-1H-benzo[d]imidazole hydrochloride AldrichCPR C12H16ClN3
CDS015999 4-(1-benzoimidazol) piperidine hydrochloride AldrichCPR C12H16ClN3
762512 2-(2-Bromophenyl)-1H-benzimidazole 95% C13H9BrN2
632600 2-(2-Chlorophenyl)benzimidazole 97% C13H9ClN2
P19809 2-Phenylbenzimidazole 97% C13H10N2
642738 2-(2-Hydroxyphenyl)-1H-benzimidazole 95% C13H10N2O
437166 2-Phenyl-5-benzimidazolesulfonic acid 96% C13H10N2O3S
642681 2-(2-Aminophenyl)-1H-benzimidazole 97% C13H11N3
CBR00351 4-(1H-Benzimidazol-1-yl)aniline AldrichCPR C13H11N3
CDS002117 N-(1H-Benzoimidazol-2-yl)-benzene-1,2-diamine AldrichCPR C13H12N4
CBR00593 2-(Piperidin-3-ylmethyl)-1H-benzimidazole AldrichCPR C13H17N3
CBR01133 4-Methyl-2-piperidin-3-yl-1H-benzimidazole dihydrochloride AldrichCPR C13H19Cl2N3
701270 2-(2-Bromophenyl)-1H-benzoimidazole-5-carboxylic acid technical grade C14H9BrN2O2
568694 2-Chloro-1-(4-fluorobenzyl)benzimidazole 97% C14H10ClFN2
CDS014808 4-(1H-1,3-benzimidazol-1-yl)benzenecarbaldehyde AldrichCPR C14H10N2O
CDS008650 3-(1H-Benzoimidazol-2-yl)-benzoic acid AldrichCPR C14H10N2O2
762563 2-(2-Bromophenyl)-1-methyl-1H-benzimidazole 97% C14H11BrN2
CDS011700 2-Benzenesulfonylmethyl-1H-benzoimidazole AldrichCPR C14H12N2O2S
CDS003967 1-Benzyl-1H-benzoimidazol-2-ylamine AldrichCPR C14H13N3
CDS002501 2-Benzyl-1H-benzimidazol-5-amine AldrichCPR C14H13N3
381586 Methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate 95% C14H18N4O3
F5396 Fenbendazole ≥98% C15H13N3O2S
BOG00031 2-Ferrocenyl-benzimidazole 97%, AldrichCPR C17H14FeN2
BOG00032 2-Ferrocenyl-6-methylbenzimidazole 97%, AldrichCPR C18H16FeN2
B153 BIT C23H28N4OS
BOG00075 2-[3-(2-Benzimidazolyl)-phenyl]-5-methyl-4-phenyl-thiazole AldrichCPR  
BOG00074 2-[3-(2-Benzimidazolyl)-phenyl)-4-phenylthiazole AldrichCPR  
BOG00077 2-[4-(2-Benzimidazolyl)-phenyl]-4-phenylthiazole AldrichCPR  
BOG00078 2-[4-(2-Benzimidazolyl)-phenyl]-5-methyl-4-phenyl-thiazole AldrichCPR  
BOG00067 6-Methyl-2-(2-thienyl)benzimidazole AldrichCPR  
BOG00076 Ethyl 2-[4-(2-benzimidazolyl)-phenyl]-4-methylthiazole-5-carboxylate AldrichCPR