Benzodioxanes

Benzodioxane derivatives, bicyclic heterocyclic systems consisting of a benzene ring fused to a heterocyclic dioxane ring, represent a series of synthetic and natural compounds of considerable medicinal importance. Compounds containing the dioxane or the 1,4-benzodioxane moiety exhibit various biological activities such as antihepatotoxic (hepatoprotective), α-adrenergic blocking agent activity, anti-inflammatory, antigrastic, spasmolytic, antipsychotic, anxiolytic, and D2 antagonist/5-HT1A partial agonist activity. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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CDS013917 5-bromo-2,2-difluoro-1,3-benzodioxole AldrichCPR C7H3BrF2O2
CDS003013 2,2-Difluoro-1,3-benzodioxole-4-carbaldehyde AldrichCPR C7H4F2O2
739383 2,2-Difluoro-1,3-benzodioxole-4-carboxaldehyde 97% C7H4F2O2
CDS015940 1,3-benzodioxole-5-sulfonyl chloride AldrichCPR C7H5ClO4S
CDS003005 5-Iodo-1,3-benzodioxole AldrichCPR C7H5IO2
CBR00760 1,3-Benzodioxol-5-ylhydrazine hydrochloride AldrichCPR C7H9ClN2O2
738913 6-Bromo-1,3-benzodioxole-5-carbonitrile 97% C8H4BrNO2
538523 6-Bromo-1,4-benzodioxane 97% C8H7BrO2
CBR00939 2,3-Dihydro-1,4-benzodioxin-6-ylhydrazine hydrochloride AldrichCPR C8H11ClN2O2
632643 2-Bromomethyl-1,4-benzodioxane 97% C9H9BrO2
532584 6-Chloroacetyl-1,4-benzodioxane 97% C10H9ClO3