Pyrroles

Pyrroles (1H-pyrroles) are heterocyclic aromatic compounds consisting of a five-membered ring containing a nitrogen atom. Pyrroles are important synthons in the synthesis of natural products. They exhibit remarkable biological properties such as hypolipidemic, antimicrobial, anti-inflammatory and antitumour activities and are able to inhibit retroviral reverse transcriptases [i.e., human immunodeficiency virus type 1 (HIV-1)], cellular DNA polymerases and protein kinases. Furthermore, some of these compounds are useful intermediates in the synthesis of biologically important naturally occurring alkaloids and unnatural heterocyclic derivatives. Phosphino-substituted N-aryl pyrroles, a novel class of sterically demanding and electron rich biaryl phosphine ligands, exhibit high turnover rates and low catalyst loadings.

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Acetylenic Schmidt Reaction
Intermolecular Hydroamination
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(2-Trimethylsilyl)-ethanesulfonyl Reagents
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131709 Pyrrole reagent grade, 98% C4H5N
CDS000078 1H-Pyrrol-1-amine AldrichCPR C4H6N2
CBR01780 4-Bromo-1H-pyrrole-2-carbonitrile AldrichCPR C5H3BrN2
668311 Pyrrole-2-carbonitrile 96% C5H4N2
ANV00088 4-Nitro-1H-pyrrole-2-carboxylic acid AldrichCPR C5H4N2O4
P73404 Pyrrole-2-carboxaldehyde 98% C5H5NO
P73609 Pyrrole-2-carboxylic acid 99% C5H5NO2
689416 Pyrrole-3-carboxylic acid ≥96% C5H5NO2
CDS004399 1H-Pyrrole-2-carboxamide AldrichCPR C5H6N2O
M5156 3-Methylpyrrole liquid C5H7N
M78801 N-Methylpyrrole 99% C5H7N
CDS009556 (1H-Pyrrol-2-yl)-methanol AldrichCPR C5H7NO
395137 2-(Trichloroacetyl)pyrrole 99% C6H4Cl3NO
424196 2-(Trifluoroacetyl)pyrrole 99% C6H4F3NO
CBR01512 4-Formyl-1H-pyrrole-2-carbonitrile AldrichCPR C6H4N2O
CDS006896 4-Cyano-1H-pyrrole-2-carboxylic acid AldrichCPR C6H4N2O2
CBR01807 4-Bromo-1-methyl-1H-pyrrole-2-carbonitrile AldrichCPR C6H5BrN2
CDS004821 5-Formyl-1H-pyrrole-2-carboxylic acid AldrichCPR C6H5NO3
CBR01777 1-Methyl-1H-pyrrole-3-carbonitrile AldrichCPR C6H6N2
689300 1-Methyl-4-nitropyrrole-2-carboxylic acid 98% C6H6N2O4
247359 2-Acetylpyrrole ReagentPlus®, 99% C6H7NO
CDS015198 3-acetylpyrrole AldrichCPR C6H7NO
130052 N-Methyl-2-pyrrolecarboxaldehyde 98% C6H7NO
153141 1-Methyl-2-pyrrolecarboxylic acid 97% C6H7NO2
CBR01791 2-Methyl-1H-pyrrole-3-carboxylic acid AldrichCPR C6H7NO2
729736 4-Methylpyrrole-2-carboxylic acid 97% C6H7NO2
423998 Methyl 1-pyrrolecarboxylate 98% C6H7NO2
685399 Methyl 1H-pyrrole-3-carboxylate 97% C6H7NO2
640425 Methyl 2-pyrrolecarboxylate 97% C6H7NO2
750883 1-(2-Bromoethyl)-1H-pyrrole 97% C6H8BrN
390836 2,4-Dimethylpyrrole 97% C6H9N
D183601 2,5-Dimethylpyrrole 98% C6H9N
357715 2-Ethylpyrrole technical grade, 90% C6H9N
CDS000018 2-(1H-Pyrrol-1-yl)ethanol AldrichCPR C6H9NO
CDS015065 1-methyl-1H-pyrrole-2-carbohydrazide AldrichCPR C6H9N3O
CBR01624 N′-Hydroxy-1-methyl-1H-pyrrole-2-carboximidamide AldrichCPR C6H9N3O
247790 1-(Dimethylamino)pyrrole 99% C6H10N2
900996 2-(1H-Pyrrol-1-yl)ethanamine C6H10N2
CDS015687 4H-thieno[3,2-b]pyrrole-5-carbonyl chloride AldrichCPR C7H4ClNOS
CBR01756 4-Bromo-1,5-dimethyl-1H-pyrrole-2-carbonitrile AldrichCPR C7H7BrN2
CBR01774 4-Bromo-1-ethyl-1H-pyrrole-2-carbonitrile AldrichCPR C7H7BrN2
CBR01832 4-Bromo-5-ethyl-1H-pyrrole-2-carbonitrile AldrichCPR C7H7BrN2
CDS002287 1-Vinyl-1H-pyrrole-2-carboxylic acid AldrichCPR C7H7NO2
729787 Ethyl 4-bromopyrrole-2-carboxylate 97% C7H8BrNO2
ANV00082 Methyl 4-bromo-1-methyl-1H-pyrrole-2-carboxylate AldrichCPR C7H8BrNO2
902861 Methyl 4-bromo-1-methyl-1H-pyrrole-2-carboxylate C7H8BrNO2
CDS016184 methyl 5-(chlorosulfonyl)-1-methyl-1H-pyrrole-2-carboxylate AldrichCPR C7H8ClNO4S
199427 1,5-Dimethyl-2-pyrrolecarbonitrile 99% C7H8N2
C91352 1-(2-Cyanoethyl)pyrrole ≥99% C7H8N2
CDS008742 2,5-Dimethyl-1H-pyrrole-3-carbaldehyde AldrichCPR C7H9NO
160865 2-Acetyl-1-methylpyrrole 98% C7H9NO
CDS000726 2-Propionylpyrrole AldrichCPR C7H9NO
640514 3,5-Dimethylpyrrole-2-carboxaldehyde 95% C7H9NO
309869 3-Acetyl-1-methylpyrrole 99% C7H9NO
CBR01642 5-Ethyl-1H-pyrrole-2-carbaldehyde AldrichCPR C7H9NO
CBR01594 1,5-Dimethyl-1H-pyrrole-2-carboxylic acid AldrichCPR C7H9NO2
687545 1H-Pyrrole-1-propionic acid 97% C7H9NO2
CDS005420 2,4-Dimethyl-1H-pyrrole-3-carboxylic acid AldrichCPR C7H9NO2
CDS000975 Ethyl 1H-pyrrole-2-carboxylate AldrichCPR C7H9NO2
ANV00044 Methyl 4-amino-1-methyl-1H-pyrrole-2-carboxylate hydrochloride AldrichCPR C7H11ClN2O2
T80306 1,2,5-Trimethylpyrrole 99% C7H11N
CBR01483 2-(1-Methyl-1H-pyrrol-2-yl)ethanamine AldrichCPR C7H12N2
CDS020018 Octahydrocyclopenta[c]pyrrole AldrichCPR C7H13N
CDS013953 1-(1,3-Thiazol-2-yl)-1H-pyrrole-2-carbaldehyde AldrichCPR C8H6N2OS
CBR01659 1-Cyclopropyl-1H-pyrrole-2-carbaldehyde AldrichCPR C8H9NO
CDS019192 3,5-Dimethyl-4-formyl-2-pyrrolecarboxylic acid AldrichCPR C8H9NO3
CDS010027 5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid AldrichCPR C8H9NO3
685410 Methyl 1-acetyl-1H-pyrrole-3-carboxylate 95% C8H9NO3
CBR01460 1,2,5-Trimethyl-1H-pyrrole-3-carbaldehyde AldrichCPR C8H11NO
CDS003863 2-acetyl-1-ethylpyrrole AldrichCPR C8H11NO
A14804 3-Acetyl-2,4-dimethylpyrrole 97% C8H11NO
CBR01375 (2,5-Dimethyl-1H-pyrrol-1-yl)acetic acid AldrichCPR C8H11NO2
CBR01386 2-(1H-Pyrrol-1-yl)butanoic acid AldrichCPR C8H11NO2
682578 4-(3-Pyrrolyl)butyric acid 95% C8H11NO2
CDS005344 Methyl 3-(1H-pyrrol-2-yl)propanoate AldrichCPR C8H11NO2
729795 Ethyl 4-(aminomethyl)pyrrole-2-carboxylate hydrochloride 97% C8H13ClN2O2
D158402 3-Ethyl-2,4-dimethylpyrrole 97% C8H13N
CDS009908 3-(1H-Pyrrol-1-yl)pyridine AldrichCPR C9H8N2
CBR00230 3-(1-Methyl-1H-pyrrol-2-yl)-1H-pyrazole-5-carboxylic acid AldrichCPR C9H9N3O2
A15002 4-Acetyl-3,5-dimethyl-2-pyrrolecarboxylic acid 95% C9H11NO3
CBR00512 5-Acetyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid AldrichCPR C9H11NO3
CDS013681 2-[4-(Methoxycarbonyl)-5-methyl-2-oxo-2,3-dihydro-1H-pyrrol-3-yl]acetic acid AldrichCPR C9H11NO5
CBR00127 1-tert-Butyl-1H-pyrrole-3-carbaldehyde AldrichCPR C9H13NO
CBR00529 4-Ethyl-3,5-dimethyl-1H-pyrrole-2-carbaldehyde AldrichCPR C9H13NO
CDS006450 3-Methyl-3-(1H-pyrrol-1-yl)butanoic acid AldrichCPR C9H13NO2
425834 N-Boc-pyrrole 98% C9H13NO2
709972 N-Boc-2,3-dihydro-1H-pyrrole 95% C9H15NO2
477516 N-Boc-2,5-dihydro-1H-pyrrole 96% C9H15NO2
CDS016022 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrrole-2-sulfonoyl chloride AldrichCPR C10H5Cl2F3N2O2S
CDS016952 1-(3-bromophenyl)-1H-pyrrole AldrichCPR C10H8BrN
452947 1-(4-Chlorophenyl)-1H-pyrrole 97% C10H8ClN
CDS000003 1-(4-Aminophenyl)-1H-pyrrole-2,5-dione AldrichCPR C10H8N2O2
131474 1-Phenylpyrrole 99% C10H9N
438839 1-(Phenylsulfonyl)pyrrole 98% C10H9NO2S
196940 1-(2-Aminophenyl)pyrrole ≥98% C10H10N2
685658 N-Boc-pyrrole-2-carboxaldehyde 97% C10H13NO3
393207 Diethyl 3,4-pyrroledicarboxylate 98% C10H13NO4
CDS004897 1-[2-(1H-Pyrrol-1-yl)ethyl]piperazine AldrichCPR C10H17N3
CDS017043 2-chloro-5-pyrrol-1-yl-benzoic acid AldrichCPR C11H8ClNO2
CDS006962 4-Chloro-3-(1H-pyrrol-1-yl)benzoic acid AldrichCPR C11H8ClNO2
CDS007385 1-(3-Fluoro-phenyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C11H8FNO
CDS004610 1-Phenyl-1H-pyrrole-2-carbaldehyde AldrichCPR C11H9NO
CDS017634 1-(4-hydroxy-phenyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C11H9NO2
368091 4-(1H-Pyrrol-1-yl)benzoic acid 99% C11H9NO2
CDS002554 5-Phenyl-1H-pyrrole-2-carboxylic acid AldrichCPR C11H9NO2
438847 1-(Phenylsulfonyl)-2-pyrrolecarboxaldehyde 97% C11H9NO3S
CDS006806 1-(3-Methyl-2-pyridinyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C11H10N2O
566322 N-Benzylpyrrole 97% C11H11N
CDS015995 [2-(1H-pyrrol-1-yl)phenyl]methanol AldrichCPR C11H11NO
466948 1-(p-Tolylsulfonyl)pyrrole 97% C11H11NO2S
CDS012765 4,5-dimethyl-2-pyrrol-1-yl-thiophene-3-carboxylic acid AldrichCPR C11H11NO2S
CDS014675 2-(1-pyrrolyl)benzylamine AldrichCPR C11H12N2
CBR00524 2-Methyl-3-(1H-pyrrol-1-yl)aniline AldrichCPR C11H12N2
CDS014332 3-(1H-Pyrrol-1-yl)benzylamine AldrichCPR C11H12N2
CDS005270 1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)-amino]-1H-pyrrole-2-carboxylic acid AldrichCPR C11H12N4O3
687456 Methyl N-Boc-2-pyrrolecarboxylate 97% C11H15NO4
ADE000058 meso-tert-Butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate AldrichCPR C11H20N2O2
CDS020196 tert-Butyl (3aR,6aR)-octahydropyrrolo[3,4-b]pyrrole-5-carboxylate AldrichCPR C11H20N2O2
CDS019398 tert-Butyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate AldrichCPR C11H20N2O2
46102 Fludioxonil PESTANAL®, analytical standard C12H6F2N2O2
CDS017645 1-benzothiazol-2-yl-1H-pyrrole-2-carbaldehyde AldrichCPR C12H8N2OS
CDS001952 1-(3,4-Dichlorobenzyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C12H9Cl2NO
CDS017126 1-(1,3-benzodioxol-5-yl)-1H-pyrrole-2-carbaldehyde AldrichCPR C12H9NO3
CDS007982 4-(2-Formyl-1H-pyrrol-1-yl)benzoic acid AldrichCPR C12H9NO3
CDS018081 4-benzoyl-1H-pyrrole-2-carboxamide AldrichCPR C12H10N2O2
CDS000775 1-(4-Methylphenyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C12H11NO
CDS007205 1-(3-Methoxy-phenyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C12H11NO2
CBR00439 3-Methyl-4-(1H-pyrrol-1-yl)benzoic acid AldrichCPR C12H11NO2
CDS017997 4-pyrrol-1-ylmethyl-benzoic acid AldrichCPR C12H11NO2
438820 3-Acetyl-1-(phenylsulfonyl)pyrrole 98% C12H11NO3S
CBR00029 2,5-Dimethyl-1-pyridin-3-yl-1H-pyrrole-3-carbaldehyde AldrichCPR C12H12N2O
740012 N-Benzyloxycarbonyl-2,3-dihydropyrrole 97% C12H13NO2
CBR00198 3-(2,5-Dimethyl-1H-pyrrol-1-yl)aniline AldrichCPR C12H14N2
D93201 Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate 97% C12H17NO4
288918 tert-Butyl 3,4,5-trimethyl-2-pyrrolecarboxylate 97% C12H19NO2
CDS018123 4-[(2,5-dimethyl-1H-pyrrol-1-yl)methyl]piperidine AldrichCPR C12H20N2
CDS019893 tert-Butyl octahydrocyclopenta[c]pyrrol-4-ylcarbamate AldrichCPR C12H22N2O2
CDS016767 1-[3-(dimethylamino)propyl]-4,5-dimethyl-3-(methylsulfonyl)-1H-pyrrol-2-amine AldrichCPR C12H23N3O2S
ALD00018 1-(2-Oxo-2-phenylethyl)-1H-pyrrole-2-carbaldehyde 95% C13H11NO2
CDS007182 3-[(2-Formyl-1H-pyrrol-1-yl)methyl]benzoic acid AldrichCPR C13H11NO3
CDS018556 1-(2-methoxy-benzyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C13H13NO2
CDS006049 2-(2,5-Dimethyl-1H-pyrrol-1-yl)benzoic acid AldrichCPR C13H13NO2
CDS002350 3-Phenyl-2-(1H-pyrrol-1-yl)propanoic acid AldrichCPR C13H13NO2
CDS018543 1-(4-dimethylamino-phenyl)-1H-pyrrole-2-carbaldehyde AldrichCPR C13H14N2O
CDS002003 2,5-Dimethyl-1-(3-methyl-2-pyridinyl)-1H-pyrrole-3-carbaldehyde AldrichCPR C13H14N2O
CDS012894 N-(2,5-Dimethyl-1H-pyrrol-1-yl)-4-hydroxybenzamide AldrichCPR C13H14N2O2
CDS017057 3-(2,5-dimethyl-1H-pyrrol-1-yl)-3-(3-thienyl)propanoic acid AldrichCPR C13H15NO2S
678058 2-[(3,5-Dimethyl-2H-pyrrol-2-ylidene)methyl]-3,5-dimethyl-1H-pyrrole monohydrochloride 97% C13H17ClN2
377945 1-(Triisopropylsilyl)pyrrole 95% C13H25NSi
CDS014356 1-Phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carbonitrile AldrichCPR C14H10N4
CDS016873 4-(2,4-dichlorobenzoyl)-N-(2-hydroxyethyl)-1H-pyrrole-2-carboxamide AldrichCPR C14H12Cl2N2O3
CDS016457 5-(4-methoxyphenyl)-1-vinyl-1H-pyrrole-2-carboxylic acid AldrichCPR C14H13NO3
CDS019779 4-(2,5-Dimethyl-pyrrol-1-ylmethyl)-benzoic acid AldrichCPR C14H15NO2
SYX00104 2-Benzylhexahydrocyclopenta[c]pyrrol-4(1H)-one AldrichCPR C14H17NO
CDS016749 (1-methyl-1H-pyrrol-2-ylmethyl)-phenethyl-amine AldrichCPR C14H18N2
288934 Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate 97% C14H21NO4
CDS016228 4-ethyl-5-phenyl-1-vinyl-1H-pyrrole-2-carboxylic acid AldrichCPR C15H15NO2
CDS013016 ([4-(2,5-Dimethyl-1H-pyrrol-1-yl)benzoyl]amino)acetic acid AldrichCPR C15H16N2O3
CDS016115 2-(2,5-dimethyl-pyrrol-1-yl)-3-phenyl-propionic acid AldrichCPR C15H17NO2
CDS006045 2-(2,5-dimethyl-pyrrol-1-yl)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid AldrichCPR C15H17NO2S
717223 11-(1H-pyrrol-1-yl)undecane-1-thiol 96% C15H27NS
ALD00020 2-((1-(2-Oxo-2-phenylethyl)-1H-pyrrol-2-yl)methylene)malononitrile 97% C16H11N3O
571903 Diethyl 1-benzyl-3,4-dihydroxy-1H-pyrrole-2,5-dicarboxylate 98% C17H19NO6
288950 Methyl 5-(benzyloxycarbonyl)-2,4-dimethyl-3-pyrrolepropionate 97% C18H21NO4
ALD00022 Diethyl 2-((1-(2-oxo-2-phenylethyl)-1H-pyrrol-2-yl)methylene)malonate 97% C20H21NO5
379085 Diethyl 5,5′-methylenebis(4-ethyl-3-methyl-2-pyrrolecarboxylate) 97% C21H30N2O4
CDS020507 8-(4-Methylphenyl)-2-(4-[(1-methyl-1H-pyrrol-2-yl)carbonyl]piperazin-1-yl)quinoline AldrichCPR C26H26N4O