Indazoles

Indazole moieties differ from indole only by the presence of an additional ring nitrogen, and thus exhibit excellent potential as bioisosteres of the indole ring system. Various indazoles display significant activity as antifungals, antiinflammatory agents, antiarrhythmic agents, analgesics, and nitric oxide synthase inhibitors. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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Indoles and Indole Isosteres

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ADE000066 6-Bromo-1H-pyrazolo[4,3-b]pyridin-3-amine AldrichCPR C6H5BrN4
717525 3-Bromoindazole 95% C7H5BrN2
776610 4-Bromo-1H-indazole 95% C7H5BrN2
702293 5-Bromo-1H-indazole 97% C7H5BrN2
702447 6-Bromo-1H-indazole 95% C7H5BrN2
717088 7-Bromo-1H-indazole 97% C7H5BrN2
335207 3-Chloroindazole 97% C7H5ClN2
729922 4-Chloro-1H-indazole 97% C7H5ClN2
CDS006550 5-Chloro-1H-indazole AldrichCPR C7H5ClN2
CDS006195 6-Chloro-1H-indazole AldrichCPR C7H5ClN2
701025 5-Fluoro-1H-indazole 97% C7H5FN2
CDS006466 6-Fluoro-1H-indazole AldrichCPR C7H5FN2
729930 4-Iodo-1H-indazole 95% C7H5IN2
708100 3-Bromo-1H-indazole-5-carboxaldehyde 95% C8H5BrN2O
764426 6-Bromo-1H-indazole-4-carboxaldehyde 97% C8H5BrN2O
708097 3-Bromo-1H-indazole-5-carboxylic acid 97% C8H5BrN2O2
764418 6-Bromo-1H-indazole-4-carboxylic acid 97% C8H5BrN2O2
708119 3-Chloro-1H-indazole-5-carboxaldehyde 95% C8H5ClN2O
717215 3-Bromo-1-methylindazole 97% C8H7BrN2
774979 5-Bromo-6-methyl-1H-indazole 97% C8H7BrN2
700967 5-Bromo-7-methyl-1H-indazole 97% C8H7BrN2
CVT00005 (6-Bromo-1H-indazol-4-yl)methanol AldrichCPR C8H7BrN2O
764434 4-(Aminomethyl)-6-bromo-1H-indazole 97% C8H8BrN3
CVT00004 Methyl 6-bromo-3-chloro-1H-indazole-4-carboxylate AldrichCPR C9H6BrClN2O2
CVT00003 Methyl 6-bromo-3-iodo-1H-indazole-4-carboxylate AldrichCPR C9H6BrIN2O2
CVT00002 Methyl 6-bromo-3-nitro-1H-indazole-4-carboxylate AldrichCPR C9H6BrN3O4
775142 Methyl 5-bromo-1H-indazole-6-carboxylate 95% C9H7BrN2O2
CDS016025 1-methyl-1H-indazole-3-carbonyl chloride AldrichCPR C9H7ClN2O
CDS020523 4-Bromo-1,5-dimethyl-1H-indazole AldrichCPR C9H9BrN2
CDS020525 5-Bromo-1,6-dimethyl-1H-indazole AldrichCPR C9H9BrN2
CBR01383 4-Chloro-1-ethyl-1H-indazol-3-amine AldrichCPR C9H10ClN3
CBR01202 3-(4,5,6,7-Tetrahydro-2H-indazol-3-yl)propanoic acid hydrochloride AldrichCPR C10H15ClN2O2
ANV00139 3-Iodo-6-nitro-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-Indazole AldrichCPR C13H18IN3O3Si