Pyridazine, sometimes called 1,2-diazine, is a six-membered ring containing two adjacent nitrogen atoms. Pyridazine is a privileged structure in medicinal chemistry and can be used as an isosteric replacement of phenyl or heteroaromatic rings. Pyridazines can improve the physiochemical properties of drug molecules by increasing their water solubility, participating as hydrogen bond acceptors, and have a high capacity to complex with targets due to their dipole moment. Pyridazine confers bioavailability, especially to the CNS, and can reduce toxicity. Pyridazine is a part of several drug molecules, and the pyradzine pharmacophore has led to a variety of pharmacologically active compounds. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

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738255 3,6-Dibromopyridazine 97% C4H2Br2N2
D73200 3,6-Dichloropyridazine 97% C4H2Cl2N2
303097 4,5-Dichloro-3-hydroxypyridazine 98% C4H2Cl2N2O
708364 3,6-Diiodopyridazine 97% C4H2I2N2
CDS020016 3-Amino-4-bromo-6-chloropyridazine AldrichCPR C4H3BrClN3
759430 3-Amino-6-chloropyridazine 97% C4H4ClN3
741272 3,6-Dichloro-4-(trifluoromethyl)pyridazine 95% C5HCl2F3N2
297755 3,6-Dichloropyridazine-4-carboxylic acid 98% C5H2Cl2N2O2
734004 4-(Trifluoromethyl)pyridazine 97% C5H3F3N2
297747 3,6-Dichloro-4-methylpyridazine 97% C5H4Cl2N2
597716 4,5-Dichloro-2-methyl-3(2H)-pyridazinone 97% C5H4Cl2N2O
637637 3-Chloro-6-methylpyridazine 97% C5H5ClN2
108596 3-Chloro-6-methoxypyridazine 95% C5H5ClN2O
ANV00010 3-Bromo-6-chloroimidazo[1,2-b]pyridazine AldrichCPR C6H3BrClN3
CDS003940 3-Chloro-6-(4-iodo-1H-pyrazol-1-yl)pyridazine AldrichCPR C7H4ClIN4
126020 1,4-Dichlorophthalazine 95% C8H4Cl2N2
705519 3-Chloro-6-(1-pyrrolidinyl)pyridazine 97% C8H10ClN3
JRD0200 6,8-Dichloro-4-oxo-4H-chromene-3-carbaldehyde AldrichCPR C10H4Cl2O3
176842 1-Phenyl-4,5-dichloro-6-pyridazone ≥99% C10H6Cl2N2O
342319 3-Chloro-6-phenylpyridazine 98% C10H7ClN2
546305 6-(4-Bromophenyl)-4,5-dihydro-2H-pyridazin-3-one 97% C10H9BrN2O
CBR01164 3-(4-Chlorophenyl)-6-hydrazinopyridazine AldrichCPR C10H9ClN4
JRD0203 2-(6-Chloropyridazin-3-yl)-2-p-tolylacetonitrile AldrichCPR C13H10ClN3
534234 4-(4-Bromophenyl)-1(2H)-phthalazinone 97% C14H9BrN2O
JRD0221 2-(4-Chlorophenyl)-2-(6-chloropyridazin-3-yl)acetonitrile AldrichCPR  
JRD0220 2-(6-Chloropyridazin-3-yl)-2-(4-fluorophenyl)acetonitrile AldrichCPR