Lactones

Lactones are cyclic esters, a ring of two or more carbon atoms and a single oxygen atom with a ketone group at one of the carbons adjacent to the other oxygen. In addition to lactones being a constituent in many natural products used in the flavors and fragrances industry, lactones also exhibit antioxidant, antimicrobial, anticancer activity. Most notably, N-acyl homoserine lactones (AHLs) are one of the predominant types of autoinducers used by Gram-negative bacteria. The cell density-responsive transcriptional system called “Quorum Sensing” has attracted the attention of medicinal chemists, and indeed the scientific community, in order to understand the lactone chemical language of bacterial populations.

Learn More about Lactones
Halonium-Induced Cyclization Reactions
Chiral Dirhodium Carboxamidates: Catalysts for Highly Enantioselective Syntheses of Lactones and Lactams
New Methods in the Formation of Macrocyclic Lactams and Lactones of Biological Interest
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P5648 β-Propiolactone Grade II, ≥90% C3H4O2
M89625 Mucobromic acid 99% C4H2Br2O3
M89803 Mucochloric acid 99% C4H2Cl2O3
422363 Diketene contains copper sulfate as stabilizer C4H4O2
B59608 α-Bromo-γ-butyrolactone 97% C4H5BrO2
219126 β-Butyrolactone 98% C4H6O2
20740 γ-Butyrolactone puriss., ≥99.0% (GC) C4H6O2
B103608 γ-Butyrolactone ReagentPlus®, ≥99% C4H6O2
CDS000753 (R)-3-Hydroxy-γ-butyrolactone AldrichCPR C4H6O3
364037 α-Hydroxy-γ-butyrolactone technical grade C4H6O3
A86406 α-Angelica lactone 98% C5H6O2
226416 α-Methylene-γ-butyrolactone 97% C5H6O2
273007 γ-Methylene-γ-butyrolactone 99% C5H6O2
393568 α-Bromo-α-methyl-γ-butyrolactone 96% C5H7BrO2
124184 α-Bromo-γ-valerolactone, mixture of cis and trans 97% C5H7BrO2
117757 α-Methyl-γ-butyrolactone 98% C5H8O2
389579 δ-Valerolactone technical grade C5H8O2
V403 γ-Valerolactone ReagentPlus®, 99% C5H8O2
541389 2,2-Dimethyl-1,3-dioxolan-4-one 96% C5H8O3
H43415 4-Hydroxy-6-methyl-2-pyrone 98% C6H6O3
I16005 Isocitric acid lactone 97% C6H6O6
A13409 α-Acetylbutyrolactone ≥99% C6H8O3
210145 2,2-Dimethyl-1,3-dioxane-4,6-dione 98% C6H8O4
303143 3,6-Dimethyl-1,4-dioxane-2,5-dione 99% C6H8O4
704067 ε-Caprolactone 97% C6H10O2
303836 γ-Caprolactone 98% C6H10O2
55201 DL-α-Hydroxy-β,β-dimethyl-γ-butyrolactone purum, ≥98.0% (T) C6H10O3
370207 4,6-Dimethyl-α-pyrone 98% C7H8O2
271977 1,6-Dioxaspiro[4.4]nonane-2,7-dione 98% C7H8O4
514969 γ-Methyl-α-(trifluoromethyl)-γ-valerolactone 96% C7H9F3O2
245100 2,2,6-Trimethyl-4H-1,3-dioxin-4-one 95% C7H10O3
210153 2,2,5-Trimethyl-1,3-dioxane-4,6-dione 97% C7H10O4
115932 6-Nitrophthalide 95% C8H5NO4
P39605 Phthalide 98% C8H6O2
341266 cyclic Isopropylidene 1,1-cyclopropanedicarboxylate 99% C8H10O4
295949 1,4-Dioxaspiro[4.5]decan-2-one 95% C8H12O3
CDS019935 Butylsuccinic anhydride AldrichCPR C8H12O3
CDS001273 δ-Octanolactone AldrichCPR C8H14O2
O4008 γ-Octanoic lactone 97% C8H14O2
341231 5-(Dimethylaminomethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 99% C9H13NO4
292370 γ-Nonanoic lactone 97% C9H16O2
176451 γ-Phenyl-γ-butyrolactone 99% C10H10O2
298069 5-Decanolide ≥98% C10H18O2
D804 γ-Decanolactone 98% C10H18O2
514977 γ-Phenyl-α-(trifluoromethyl)-γ-butyrolactone,mixture of cis and trans 97% C11H9F3O2
343617 Oxacyclododecan-2-one 98% C11H20O2
291277 Undecanoic δ-lactone 98% C11H20O2
U806 Undecanoic γ-lactone 99% C11H20O2
06063 γ-Phenyl-ε-caprolactone ≥99.0% C12H14O2
298077 5-Dodecanolide 99% C12H22O2
348961 Oxacyclotridecan-2-one 98% C12H22O2
74381 (2-Nonen-1-yl)succinic anhydride technical, ≥90% (NT) C13H20O3
401773 γ-(2-Naphthyl)-γ-butyrolactone 99% C14H12O2
B1806 Benzalphthalide C15H10O2
76530 Pentadecanolide puriss., ≥99.0% (GC) C15H28O2
419133 Pentadecanolide 98% C15H28O2
H0893 16-Hexadecanolide C16H30O2
540757 16-Hexadecanolide 97% C16H30O2
631418 Benzo[k,l]xanthene-3,4-dicarboxylic anhydride C18H8O4
Z2000 β-Zearalenol ≥98% C18H24O5
CDS003207 2′,4′,5′,7′-tetrabromo-3,4,5,6-tetrachlorofluorescein AldrichCPR C20H4Br4Cl4O5
CDS019193 (-)-Pareruptorin a AldrichCPR C20H20O8
CDS000008 7-Ethylcamptothecin AldrichCPR C22H20N2O4
690341 2,3,4,6-Tetra-O-benzyl-D-gluconic acid-δ-lactone C34H34O6