Thiazoles

Thiazoles and their derivatives have been frequently discovered as a vital component of novel and structurally diverse natural products that exhibit a wide variety of biological activities. The exceptional range of antitumor, antiviral, and antibiotic activities, as well as their presence in peptides, or ability to bind to proteins, DNA, and RNA, have directed numerous synthetic studies and new applications of these heterocycles.

The thiazole ring has been identified as a central feature of a myriad of natural products, perhaps the best known being the epothilones. Additionally, thiazoles are frequently appearing in peptide research. Thiazoles can also serve as a protected formyl group that can be liberated in the late stages of a complex natural product synthesis. The presence of a halogen allows these reagents to be used as substrates in various coupling reactions, including Suzuki-Miyaura cross-coupling reactions.

Learn More about Thiazoles
Thiazoles and Imidazoles

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Description

Molecular Formula

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SYX00075 5-Bromo-2-chlorothiazole AldrichCPR C3HBrClNS
B74372 2-Bromo-5-nitrothiazole 98% C3HBrN2O2S
677914 2,4-Dibromothiazole 97% C3HBr2NS
524182 2,5-Dibromothiazole 97% C3HBr2NS
160474 2-Bromothiazole 98% C3H2BrNS
697907 4-Bromothiazole 97% C3H2BrNS
642517 5-Bromothiazole 95% C3H2BrNS
723452 2-Chlorothiazole 96% C3H2ClNS
128023 2-Amino-5-bromothiazole monohydrobromide 97% C3H3BrN2S · HBr
143456 2-Amino-5-chlorothiazole hydrochloride 95% C3H3ClN2S · HCl
754153 2-Amino-5-fluorothiazole hydrochloride 95% C3H3FN2S · HCl
720534 2-Chlorothiazole-5-carbonitrile 97% C4HClN2S
724300 2,4-Dichlorothiazole-5-carboxaldehyde 97% C4HCl2NOS
756873 2-Bromothiazole-4-carboxaldehyde C4H2BrNOS
699284 4-Bromothiazole-2-carboxaldehyde 96% C4H2BrNOS
642487 2-Bromothiazole-5-carboxylic acid 97% C4H2BrNO2S
748250 2-Bromo-4-methylthiazole 96% C4H4BrNS
646008 2-Bromo-4-methylthiazole-5-carboxylic acid 96% C5H4BrNO2S
673129 2-Acetamido-5-chlorothiazole 96% C5H5ClN2OS
708429 Ethyl 2-bromothiazole-4-carboxylate 96% C6H6BrNO2S
642495 Ethyl 2-bromothiazole-5-carboxylate 97% C6H6BrNO2S
SYX00078 5-Bromo-a,a-dimethyl-2-thiazolemethanol AldrichCPR C6H8BrNOS
717029 4-Bromo-2-(trimethylsilyl)thiazole 95% C6H10BrNSSi
667366 6-Bromo-2-chlorobenzothiazole 97% C7H3BrClNS
JRD0228 2,6-Dibromobenzo[d]thiazole AldrichCPR C7H3Br2NS
667358 2-Chloro-6-fluorobenzothiazole 97% C7H3ClFNS
767859 2-Chloro-6-nitrobenzothiazole 97% C7H3ClN2O2S
553670 2,6-Dichlorobenzothiazole 97% C7H3Cl2NS
678600 2-Bromobenzothiazole 95% C7H4BrNS
761745 5-bromobenzothiazole 97% C7H4BrNS
CDS006877 5-bromobenzothiazole AldrichCPR C7H4BrNS
CBR01457 4-Chloro-6-fluoro-1,3-benzothiazol-2-amine AldrichCPR C7H4ClFN2S
CDS020499 5-Chloro-1,2-benzisothiazol-3(2H)-one AldrichCPR C7H4ClNOS
452742 N-Chlorosaccharin 99% C7H4ClNO3S
167576 2-Chlorobenzothiazole 99% C7H4ClNS
125571 5-Chloro-2-mercaptobenzothiazole technical grade, ≥90% C7H4ClNS2
ANV00145 7-Chlorobenzo[d]thiazole-2-thiol AldrichCPR C7H4ClNS2
ANV00148 7-Fluorobenzo[d]thiazole-2-thiol AldrichCPR C7H4FNS2
683337 2-Amino-4,6-difluorobenzothiazole 97% C7H4F2N2S
647683 2-Amino-5-bromobenzothiazole 96% C7H5BrN2S
538507 2-Amino-6-bromobenzothiazole 97% C7H5BrN2S
133434 2-Amino-4-chlorobenzothiazole 97% C7H5ClN2S
136085 2-Amino-6-chlorobenzothiazole 99% C7H5ClN2S
CDS006997 4-Fluoro-1,3-benzothiazol-2-amine AldrichCPR C7H5FN2S
645990 Ethyl 2-bromo-4-methylthiazole-5-carboxylate 97% C7H8BrNO2S
724122 2-Bromo-4-tert-butylthiazole 97% C7H10BrNS
761753 5-Bromo-2-methylbenzothiazole 95% C8H6BrNS
667331 2-Chloro-6-methoxybenzothiazole 97% C8H6ClNOS
667374 2-Chloro-6-methylbenzothiazole 96% C8H6ClNS
545775 5-Chloro-2-methylbenzothiazole 97% C8H6ClNS
CBR00935 (1,3-Benzothiazol-2-ylmethyl)amine hydrochloride AldrichCPR C8H9ClN2S
CDS005761 4-bromo-2-(4-hydroxypiperidin-1-yl)thiazole AldrichCPR C8H11BrN2OS
688177 2-Chloro-4-(4-bromophenyl)thiazole 97% C9H5BrClNS
688169 2-Chloro-4-(4-chlorophenyl)thiazole 97% C9H5Cl2NS
688126 4-(4-Bromophenyl)-2-hydroxythiazole 96% C9H6BrNOS
719617 2-Bromo-4-phenylthiazole 97% C9H6BrNS
686158 4-(4-Bromophenyl)-2-thiazolethiol 97% C9H6BrNS2
688134 4-(4-Chlorophenyl)-2-hydroxythiazole 97% C9H6ClNOS
688150 2-Chloro-4-phenylthiazole 97% C9H6ClNS
683280 2-Amino-4-(2,4-difluorophenyl)thiazole 97% C9H6F2N2S
534129 2-Amino-4-(4-bromophenyl)thiazole 97% C9H7BrN2S
339369 2-Amino-4-(4-chlorophenyl)thiazole 98% C9H7ClN2S
CDS011142 5-chloro-N-ethyl-1,3-benzothiazol-2-amine AldrichCPR C9H9ClN2S
445436 Ethyl 2-(2-chloroacetamido)-4-thiazoleacetate 98% C9H11ClN2O3S
JRD0109 4-(4-Chlorophenyl)-5-methylthiazol-2-amine AldrichCPR C10H9ClN2S
CDS001986 4-(4-Fluoro-3-methylphenyl)-1,3-thiazol-2-ylamine AldrichCPR C10H9FN2S
JRD0110 4-(4-fluoro-phenyl)-5-methyl-thiazol-2-ylamine AldrichCPR C10H9FN2S
653497 4-(4-Bromophenyl)-2-thiazoleacetonitrile 97% C11H7BrN2S
CDS007013 [2-(3-bromo-phenyl)-thiazol-4-yl]-acetic acid AldrichCPR C11H8BrNO2S
CDS013453 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid AldrichCPR C11H8ClNO2S
CDS017045 n1-(4-phenyl-1,3-thiazol-2-yl)-2-chloroacetamide AldrichCPR C11H9ClN2OS
CDS015877 5-(bromomethyl)-4-methyl-2-phenyl-1,3-thiazole AldrichCPR C11H10BrNS
653500 Ethyl 2-amino-4-(4-bromophenyl)thiazole-5-carboxylate 90% C12H11BrN2O2S
717258 Ethyl-4-(bromomethyl)-2-(2-pyridyl)thiazole-5-carboxylate 97% C12H11BrN2O2S
CDS020131 N-(2-Chlorophenyl)-1,3-benzothiazol-2-amine AldrichCPR C13H9ClN2S
CDS011609 benzothiazol-2-yl-(4-fluoro-phenyl)-amine AldrichCPR C13H9FN2S
CDS008062 4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]aniline AldrichCPR C15H11FN2S
SYX00111 2-Chloro-4-(tributylstannyl)thiazole AldrichCPR C15H28ClNSSn
JRD0285 (2-Bromo-4-methylthiazol-5-yl)methanol AldrichCPR