Serine - Unnatural Amino Acids and Derivatives

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Serine is a functionally important non-essential amino acid, synthesized by the human body . With an alcohol group, it is required for the metabolism of fatty acids and cell membranes, muscle growth and a healthy immune system. Serine is found at the active site of the serine protease enzyme class, that includes trypsin and chymotrypsin. Unnatural serine amino acids are non-proteinogenic that are chemically synthesized. They are utilized as chiral building blocks, conformational constraints, molecular scaffolds or pharmacologically active products. Sigma-Aldrich offers a large number of different non-natural ser amino acids, which are routinely used in peptide synthesis.

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444375 N-Benzoyl-(2R,3S)-3-phenylisoserine 98% C16H15NO4
30020 D-Cycloserine C3H6N2O2
776572 Fmoc-Gly-Val-OH 95% C22H24N2O5
772445 Fmoc-Ser[GalNAc(Ac)3-α-D]-OH 95% C32H36N2O13
06054 L-Isoserine ≥98.0% (TLC) C3H7NO3
286338 DL-Isoserine 98% C3H7NO3
171603 DL-3-Phenylserine hydrate 98% C9H11NO3 · xH2O