PEG Azides

PEG polymers contain numerous inherent favorable biological characteristics including high water solubility and a lack of toxicity and immunogenicity. Thus, the chemical modification of biologically active compounds, such as peptides, antibody fragments, enzymes, or small molecules with polyethylene glycol chains, referred to as “PEGylation”, often leads to improved pharmacokinetics and biological function in many applications. PEG azides are ideal starting materials for the synthesis of PEG derivatives via azide-alkyne cycloaddition or Staudinger ligation.

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Polyethylene Glycol Building Blocks for PEGylation
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Product #



Molecular Formula

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76318 O-(2-Aminoethyl)-O′-(2-azidoethyl)heptaethylene glycol ≥90% (oligomer purity) C18H38N4O8
77787 O-(2-Aminoethyl)-O′-(2-azidoethyl)nonaethylene glycol ≥90% (oligomer purity) C22H46N4O10
76172 O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol ≥90% (oligomer purity) C14H30N4O6
QBD10502 Azido-dPEG®4-acid C11H21N3O6
QBD10512 Azido-dPEG®8-acid C19H37N3O10
QBD10513 Azido-dPEG®12-acid C27H53N3O14
QBD10514 Azido-dPEG®24-acid C51H101N3O26
QBD10523 Azido-dPEG®7-amine C16H34N4O7
QBD10524 Azido-dPEG®11-amine C24H50N4O11
QBD10525 Azido-dPEG®23-amine C48H98N4O23
QBD10526 Azido-dPEG ®35-amine >90% C72H146N4O35
QBD10501 Azido-dPEG®4-NHS ester C15H24N4O8
QBD10503 Azido-dPEG®8-NHS ester C23H40N4O12
QBD10505 Azido-dPEG®12-NHS ester C31H56N4O16
QBD10567 Azido-dPEG ®4-TFP ester C17H21F4N3O6
QBD10569 Azido-dPEG ®12-TFP ester >90% C33H53F4N3O14
QBD10571 Azido-dPEG ®24-TFP ester C57H101F4N3O26
QBD10573 Azido-dPEG ®36-TFP ester C81H149F4N3O38
727423 2-[2-(2-Azidoethoxy)ethoxy]ethanol solution ~0.5 M in tert-butyl methyl ether C6H13N3O3
901152 1-Azido-2-(2-(2-ethoxyethoxy)ethoxy)ethane ≥95% C8H17N3O3
71613 O-(2-Azidoethyl)-O-[2-(diglycolyl-amino)ethyl]heptaethylene glycol ≥90% (oligomer purity) C22H42N4O12
689440 O-(2-Azidoethyl)heptaethylene glycol ≥95% (oligomer purity) C16H33N3O8
712590 O-(2-Azidoethyl)-O′-methyl-triethylene glycol ≥90% (NMR) C9H19N3O4
712604 O-(2-Azidoethyl)-O′-methyl-undecaethylene glycol ≥90% (NMR) C25H51N3O12
901132 1-Azido-2-(2-(2-methoxyethoxy)ethoxy)ethane C7H15N3O3
804665 Azido-PEG4-phenyloxadiazole methylsulfone ≥95% C17H23N5O7S
901155 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine C12H26N4O5
744751 14-Azido-3,6,9,12-tetraoxatetradecanoic acid solution ~0.5 M in tert-butyl methyl ether, ≥90% (HPLC) C10H19N3O6
17758 11-Azido-3,6,9-trioxaundecan-1-amine technical, ≥90% (GC) C8H18N4O3
QBD11217 Bromoacetamido-dPEG ®3-azide C10H19BrN4O4
QBD11204 Bromoacetamido-dPEG ®11-azide C26H51BrN4O12
QBD11205 Bromoacetamido-dPEG ®23-azide C50H99BrN4O24
901991 Dde biotin picolyl azide C38H57N9O9S
901136 1,17-Diazido-3,6,9,12,15-pentaoxaheptadecane C12H24N6O5
901140 1,14-Diazido-3,6,9,12-tetraoxatetradecane C10H20N6O4
765953 1,11-Diazido-3,6,9-trioxaundecane C8H16N6O3
689807 Methoxypolyethylene glycol azide PEG average Mn 2,000  
689475 Methoxypolyethylene glycol azide  
901763 PC biotin-azide C35H55N9O12S
689696 Polyoxyethylene bis(azide) average Mn 2,000  
689580 Polyoxyethylene bis(azide) average Mn 5,000