Solvent Center

Sure/Seal™ Packaging System

Our Sure/Seal™ System

As the leader in air-sensitive chemistry, we carry the largest breadth of anhydrous solvents and air-sensitive reagents to service the research market. In the late 1970’s, our Sure/Seal™ bottle was developed to protect our growing line of air-sensitive reagents from oxygen and moisture. Our Sure/Seal™ bottle not only maintains product integrity, but also facilitates the use of these products. While the crimp cap ensures an air-tight seal, the liner provides greater resealing qualities to further improve our Sure/Seal™ system.

Crimp Cap Design

  • Increased puncture area by 4x to accommodate multiple punctures
  • Crimp cap helps maintain product quality by providing an air-tight system
New Sure/Seal™ bottle
 Sure/Seal™ bottle
Past Sure/Seal™ bottle
 Past style

Plug Style

  • Maximimizes surface area contact with the bottle to prevent moisture and oxygen entry
  • More than 50% thicker than competing brands

Elastomer Composition

  • Provides outstanding resealing properties
  • Secondary resin layer ensures resistance to chemicals
  • Outperforms competing seals with respect to moisture uptake 

Sure/Seal™ bottle Testing Results
To illustrate the effectiveness of our Sure/Seal™ system, we evaluated it against another supplier (Competitor A) to see how each performed when tested for Oxygen Transmission (OTR), Moisture uptake and Liner Integrity after repetitive puncturing.

Unpunctured Sure/Seal™ Bottle
4 Punctures Sure/Seal™ Bottle
4 Punctures

To see the complete product list visit our Sure/Seal™ Bottles page.


New Sure/Seal™ Brochure
New Sure/Seal™ Brochure

Performance Testing

Moisture Analysis

Testing Results (KF)

Karl Fischer utilizes a coulometric titration method to measure the rate of moisture uptake. To determine the effectiveness of the liner’s seals and closure designs, a five-week study was conducted using a dried 18g needle, triplicate sample sets from 100 mL bottles received four new punctures per liner each week (5 weeks total) throughout the test schedule for a total of 20 punctures per liner. At the end of each interval, the overcaps were secured by torquing the cap using a force of 40 in-lbs.

Test Results (KF)







Other Test Solvents

Solvents Tested Average Weekly Moisture Gain (5 weeks)
Sure/Seal bottle Competitor A
Chloroform ~ 1.1 ppm ~ ~11.6 ppm
Dichloromethane ~ 2.2 ppm ~ 14.5 ppm
1,4-Dioxane ~ 4.2 ppm ~ 36.4 ppm
n-Hexane * <1 ppm change <1 ppm change
Pyridine ~ 5.4ppm ~45.3 ppm
Toluene ~ 1.7 ppm ~ 7.3ppm



* Virtually no change within testing variance. The initial water content was subtracted from successive testing values to normalize the concentration of water over time.

Comprehensive testing confirms the Sure/Seal™ bottle outperforms other products on the market by maintaining low water absorption even after multiple punctures.

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Linear Integrity

When using air-sensitive solvents and reagents, liners should not only seal to maintain product quality, but also consistently maintain form after repeated punctures. 

Toluene Testing – 5weeks (20 punctures)
Competitor A
Sure/Seal™ bottle

n-Hexane Testing
New Sample
0 Punctures
Week 2
8 Punctures
Week 4
16 Punctures
Week 6
24 Punctures
Competitor A
compnopunctures compeightpunctures compsixteenpunctures comptwentyfourpunctures
Sure/Seal™ bottle
ssunpunctured sseightpunctures sssixteenpunctures sstwentyfourpunctures

Above photos illustrate the affects of repetitive punctures (4 per week) using a dried 18g needle


Our liner configuration was not prone to upwardly swelling nor did it show evidence of bowing. It was apparent that Competitor A’s liner demonstrated dramatic liner damage during the repetitive puncture testing in both the Toluene and n-Hexane (however significant water gain was not observed in n-Hexane) samples.

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To see the complete product list visit our Sure/Seal™ Bottles page.

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Oxygen Transmission Rate TestingOxygen Transmission Rate Testing

A measurement of the amount of O2 allowed to permeate into the bottle over a period of time. This test demonstrates the cap and liners ability to maintain an air-tight seal.

Oxygen Transmission Rate Testing

Overcaps were torqued to 40 lbs per square and liners were punctured four times with an 18g needle.

OTR testing demonstrates our New Sure/Seal™ system is better suited to sustain product quality than that of “Competitor A”.

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