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Amino Acids and Derivatives

Stable Isotope Labeled Amino Acids and Derivatives for Biomolecular NMR

In structural genomics, the use of biomolecular NMR to study protein structure and function relies heavily on the use of stable isotope labeled proteins. In order to incorporate the stable isotope label into these proteins, researchers use labeled amino acids in a variety of methods that include peptide synthesis, cell-free protein synthesis, and microbial growth by media. Labeled amino acids provide the ability to incorporate 13C, 15N, and/or deuterium labels into the protein allowing the user a significant level of flexibility to create uniform, selective, or site-specific labeling patterns throughout the protein structure.

ISOTEC Stable Isotopes offers a full line of protected and unprotected amino acids labeled with 13C, 15N and/or deuterium. Our complete product line includes amino acid mixtures as well as all twenty amino acids with a variety of labeling patterns for all of your research needs. Contact Us for any questions, to request a quote or to place an order.

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Amino Acid Mixtures

Product #

Description

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426199 Algal amino acid mixture-13C 98 atom % 13C
487910 Algal amino acid mixture-13C,15N 98 atom % 13C, 98 atom % 15N
608947 Algal amino acid mixture-15N 98 atom % 15N
607649 Algal amino acid mixture-13C,15N,d 98 atom % 13C, 97 atom % D, 98 atom % 15N
596906 Algal amino acid mixture-15N,d 97 atom % D, 98 atom % 15N
767964 Cell Free Amino Acid Mixture - 13C,15N 98 atom % 15N, 98 atom % 13C, ~5-100 mM in water
767972 Cell Free Amino Acid Mixture-15N 98 atom % 15N, ~5-100 mM in water
771031 Cell Free Amino Acid Mixture-13C, 15N, D 98 atom % 13C, 98 atom % 15N, 97 atom % D, ~2-100 mM in water

Amino Acids and Derivatives

Product #

Description

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489867 L-Alanine-1-13C 99 atom % 13C
485853 L-Alanine-2-13C,15N 98 atom % 15N, 99 atom % 13C
489883 L-Alanine-13C3,15N 98 atom % 15N, 98 atom % 13C
740055 L-Alanine-3-13C, 2-d 97 atom % D, 99 atom % 13C, 98% (CP)
332127 L-Alanine-15N 98 atom % 15N
600113 L-Arginine-15N4 hydrochloride 98 atom % 15N, 97% (CP)
608033 L-Arginine-13C6,15N4 hydrochloride 99 atom % 15N, 99 atom % 13C, 95% (CP)
485918 L-Asparagine-15N2 monohydrate 98 atom % 15N, 98% (CP)
636673 L-Asparagine-15N2,d8 98 atom % D, 98 atom % 15N, 98% (CP)
608157 L-Asparagine-13C4,15N2 monohydrate 98 atom % 15N, 98 atom % 13C, 95% (CP)
572519 L-Aspartic acid-15N,2,3,3-d3 98 atom % 15N, 98 atom % D
607835 L-Aspartic acid-13C4,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
332135 L-Aspartic acid-15N 98 atom % 15N
658057 L-Cysteine-13C3,15N ≥99 atom %, ≥98% (CP)
609129 L-Cysteine-15N 98 atom % 15N, 95% (CP)
607851 L-Glutamic acid-13C5,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
332143 L-Glutamic acid-15N 98 atom % 15N
490032 L-Glutamine-15N2 98 atom % 15N
607983 L-Glutamine-13C5,15N2 98 atom % 13C, 98 atom % 15N
635081 L-Glutamine-13C5,15N2,d10 98 atom % 13C, 96 atom % D, 98 atom % 15N, 95% (CP)
299294 Glycine-15N 98 atom % 15N
489522 Glycine-13C2,15N 98 atom % 15N, 99 atom % 13C
574368 L-Histidine-15N3 95 atom % 15N
608092 L-Isoleucine-13C6,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
609013 L-Isoleucine-15N 98 atom % 15N, 98% (CP)
608068 L-Leucine-13C6,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
340960 L-Leucine-15N 98 atom % 15N
609021 L-Lysine-15N2 hydrochloride 98 atom % 15N, 98% (CP)
608041 L-Lysine-13C6,15N2 hydrochloride 99 atom % 13C, 99 atom % 15N, 95% (CP)
608106 L-Methionine-13C5,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
609242 L-Methionine-15N 98 atom % 15N, 98% (CP)
608017 L-Phenylalanine-13C9,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
490105 L-Phenylalanine-15N 98 atom % 15N
608114 L-Proline-13C5,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)
608998 L-Proline-15N ≥95 atom % 15N, 98% (CP)
608130 L-Serine-13C3,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
609005 L-Serine-15N 98 atom % 15N, 98% (CP)
703443 Taurine-1,1,2,2-d4 99 atom % D, 98% (CP)
607770 L-Threonine-13C4,15N 98 atom % 13C, 98 atom % 15N
609099 L-Threonine-15N 98 atom % 15N, 98% (CP)
574600 L-Tryptophan-15N2 95 atom % 15N, 95% (CP)
574597 L-Tryptophan-13C11,15N2 ≥99 atom %, ≥98% (CP)
607991 L-Tyrosine-13C9,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
332151 L-Tyrosine-15N 98 atom % 15N
600148 L-Valine-13C5,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)
490172 L-Valine-15N 98 atom % 15N

Protected Amino Acids

Product #

Description

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486760 Boc-Ala-OH-1-13C 99 atom % 13C
489913 Boc-Ala-OH-15N ≥98 atom % 15N, ≥99% (CP)
486698 Boc-Gly-OH-1-13C 99 atom % 13C
486701 Boc-Gly-OH-15N 98 atom % 15N, 99% (CP)
489557 Boc-Gly-OH-2-13C,15N 98 atom % 15N, 99 atom % 13C
587710 Boc-Gly-OH-2,2-d2 98 atom % D
486752 Fmoc-Ala-OH-1-13C 99 atom % 13C
489905 Fmoc-Ala-OH-15N 98 atom % 15N
605131 Fmoc-Ala-OH-13C3 99 atom % 13C, 99% (CP)
489956 Fmoc-Ala-OH-3-13C 99 atom % 13C
485888 Fmoc-Ala-OH-3,3,3-d3 99 atom % D
609153 Fmoc-Glu(OtBu)-OH-15N 98 atom % 15N, 99% (CP)
605182 Fmoc-Gly-OH-1-13C 99 atom % 13C
485756 Fmoc-Gly-OH-15N 98 atom % 15N
489530 Fmoc-Gly-OH-13C2,15N 99 atom % 13C, 98 atom % 15N
603457 Fmoc-Gly-OH-2-13C,15N 99 atom % 13C, 98 atom % 15N
485772 Fmoc-Gly-OH-2,2-d2 98 atom % D
578622 Fmoc-Ile-OH-15N 98 atom % 15N, 99% (CP)
597228 Fmoc-Ile-OH-13C6,15N 98 atom % 15N, 98 atom % 13C, 98% (CP)
485934 Fmoc-Leu-OH-1-13C 99 atom % 13C
485950 Fmoc-Leu-OH-15N 98 atom % 15N, 98% (CP)
609196 Fmoc-Met-OH-15N 98 atom % 15N
651443 Fmoc-Phe-OH-13C9,15N 98 atom % 13C, 98 atom % 15N, 98% (CP)
609145 Fmoc-Ser(tBu)-OH-15N 98 atom % 15N
486000 Fmoc-Val-OH-15N 98 atom % 15N
616087 Fmoc-Val-OH-d8 98 atom % D