Strat-M® 透皮扩散膜

体验Strat-M®膜无与伦比的可预测性,Strat-M®膜是一种用于透皮扩散测试的合成非动物基膜,其在人体皮肤上的扩散行为可预测,不同批次的产品之间不存在差异,不存在安全性或储存限制。

 

专为透皮扩散和安全测试而设计:
  • 美容活性成分
  • 配方
  • 个人护理产品
  • 活性药物成分(API)
  • 农药和化学品
 
 

Strat-M® 膜相关数据

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Strat-M® 透皮扩散膜视频

观看Strat-M®膜是如何克服对人体皮肤上的扩散进行预测这一障碍的。

 

 

 

Strat-M®应用:预测透皮扩散

我们汇编了一系列引用Strat-M®、经过同行评审后所发表的研究,这些研究详细介绍了将其用于皮肤扩散测试的步骤。

  1. Dermal toxicity elicited by phthalates: Evaluation of skin absorption, immunohistology, and functional proteomics. Tai-Long Pan et al., Food and Chemical Toxicology 65 (2014) 105–114.
  2. Prediction of skin permeation by chemical compounds using the artificial membrane, Strat-M™. Takashi Uchida et al., European Journal of Pharmaceutical Sciences 67 (2015) 113–118.
  3. In vitro skin models as a tool in optimization of drug formulation. Goril Eide Flaten et al., European Journal of Pharmaceutical Sciences 75 (2015) 10–24. (Review)
  4. Curcumin-Eudragit® E PO solid dispersion: A simple and potent method to solve the problems of curcumin. Jinglei Li et al., European Journal of Pharmaceutics and Biopharmaceutics 94 (2015) 322–332.
  5. Impact of Different Vehicles for Laser-Assisted Drug Permeation via Skin: Full-Surface versus Fractional Ablation. Woan-Ruoh Lee et al., Pharm Res (2014) 31:382–393.
  6. Preparation of a Capsaicin-Loaded Nanoemulsion for Improving Skin Penetration. Jee Hye Kim et al., J. Agric. Food Chem. 2014, 62, 725−732.
  7. A review of the current state of the art of physiologically-based tests for measuring human dermal in vitro bioavailability of polycyclic aromatic hydrocarbons (PAH) in soil, Darren J. Beriroa et al, Journal of Hazardous Materials 2016, V 305, 240–259.
  8. Using Vertical Diffusion Cells. Sumalatha Nallagundla et al, AAPS PharmSciTech, Vol. 15, No. 4, 2014, 994 – 999.Comparison of In Vitro Release Rates of Acyclovir from Cream Formulations.