功能基因组学和RNAi

TRC文库引用

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MISSION® TRC1.5人类和小鼠shRNA文库是适用于小规模至高通量RNAi筛选的成熟产品。在下文内容中,您将看到研究人员发表在同行评议期刊上的精选文章,这些文章使用TRC1/1.5文库并引用博德研究所(Broad Institute)和Sigma-Aldrich作为其高品质试剂来源。与其他shRNA文库不同,这些文章引用的克隆与Sigma-Aldrich可提供的克隆相同。如果某个克隆无法在我们的目录中找到,请联系MISSIONRNAi@sial.com咨询。

如何引用TRC文库

在科学出版物中,人类文库应被称为MISSION® TRC-Hs 1.0(人类),而小鼠文库应被称为MISSION® TRC-Mm 1.0(小鼠)。如果您的TRC文库购买于2011年7月之后,则人类文库应被称为MISSION® TRC-Hs 1.5 (人类),而小鼠文库应被称为MISSION® TRC-Mm 1.5 (小鼠)。如果您的实验使用了我们的TRC2文库,则人类文库应被称为MISSION® TRC-Hs 2.0 (人类),而小鼠文库应被称为MISSION® TRC-Mm 2.0(小鼠)。单独的克隆应通过其特殊的TRC编号进行鉴别(如MISSION® TRC shRNA TRCN0000030720)。

 

MISSION® shRNA 引文
标题 作者/期刊 摘要
Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma. Lachke, S.A. et al.
Science. 2011. 331: 1571-1576
摘要
Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species. Sevlever, D. et al.
Biochemistry. 2008. 47: 9678-9687
摘要
EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance. Zhang, Y, et al.
Molecular Cancer Therapeutics. 2008.7:3176.
摘要
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Zhang, XY, et al.
Mol Cell. 2008.29: 102-11.
摘要
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Zeng, X, et al.
Development. 2008.135: 367-75.
摘要
Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest. Yang, WS, et al.
Genome Biol. 2008.9: R92.
摘要
Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene. Yamashita, M, et al.
J Exp Med. 2008.205: 1109-20.
摘要
Elevated protein tyrosine phosphatase activity provokes Eph/ephrin-facilitated adhesion of pre-B leukemia cells. Wimmer-Kleikamp, SH, et al.
Blood. 2008.112: 721-32.
摘要
Immunization with a mimotope of GD2 ganglioside induces CD8+ T cells that recognize cell adhesion molecules on tumor cells. Wierzbicki, A, et al.
J Immunol. 2008.181: 6644-53.
摘要
Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells. Wei, D, et al.
Cancer Res. 2008.68: 4631-9.
摘要
Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and beta-arrestin1. Vasilcanu, R, et al.
Oncogene. 2008.27: 1629-38.
摘要
Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway. Varghese, B, et al.
Mol Cell Biol. 2008.28: 5275-87.
摘要
Up-regulation of c-FLIP short by NFAT contributes to apoptosis resistance of short-term activated T cells. Ueffing, N, et al.
Blood. 2008.112: 690-8.
摘要
Inhibition of" self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. Tsai, R, et al.
The Journal of Cell Biology. 2008.180:989.
摘要
Phospholipase D1 is an effector of Rheb in the mTOR pathway. Sun, Y, et al.
Proc Natl Acad Sci U S A. 2008.105: 8286-91.
摘要
The beta1 integrin activates JNK independent of CagA, and JNK activation is required for Helicobacter pylori CagA+-induced motility of gastric cancer cells. Snider, JL, et al.
J Biol Chem. 2008.283: 13952-63.
摘要
Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages. Sierra, J, et al.
Journal of Experimental Medicine. 2008.205:1673.
摘要
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance. Shimamura, T, et al.
Cancer Res. 2008.68: 5827-38.
摘要
Differentiation of Neural Stem Cells into Oligodendrocytes: Involvement of the Polycomb Group Protein Ezh2. Sher, F, et al.
Stem Cells. 2008.26:2875.
摘要
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Shema, E, et al.
Genes & Development. 2008.22:2664.
摘要
Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms. Shaikh, FM, et al.
Exp Cell Res. 2008.314: 2941-50.
摘要
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Sen, N, et al.
Nature Cell Biology. 2008.10:866.
摘要
Downregulation of vertebrate Tel (ETV6) and Drosophila Yan is facilitated by an evolutionarily conserved mechanism of F-box-mediated ubiquitination. Roukens, MG, et al.
Mol Cell Biol. 2008.28: 4394-406.
摘要
A Sensitive Flow Cytometry-based Nucleotide Excision Repair Assay Unexpectedly Reveals That Mitogen-activated Protein Kinase Signaling Does Not Regulate the Removal of UV-induced DNA Damage in Human Cells. Rouget, R, et al.
J Biol Chem. 2008.283: 5533-41.
摘要
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. Pfister, S, et al.
J Clin Invest. 2008.118: 1739-49.
摘要
Identification of Pbx1, a Potential Oncogene, as a Notch3 Target Gene in Ovarian Cancer. Park, J, et al.
Cancer Research. 2008.68:8852.
摘要
TRIP12 functions as an E3 ubiquitin ligase of APP-BP1. Park, Y, et al.
Biochem Biophys Res Commun. 2008.374: 294-8.
摘要
SOK1 translocates from the Golgi to the nucleus upon chemical anoxia and induces apoptotic cell death. Nogueira, E, et al.
J Biol Chem. 2008.283: 16248-58.
摘要
Genetic Complementation Screen Identifies a Mitogen-activated Protein Kinase Phosphatase, MKP3, as a Regulator of Dopamine Transporter Trafficking. Mortensen, O, et al.
Molecular Biology of the Cell. 2008.19:2818.
摘要
Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. Martin-Granados, C, et al.
Int J Biochem Cell Biol. 2008.40: 2315-32.
摘要
Protein phosphatase 2A subunit PR70 interacts with pRb and mediates its dephosphorylation. Magenta, A, et al.
Mol Cell Biol. 2008.28: 873-82.
摘要
Human Cytomegalovirus Protein pp71 Displaces the Chromatin Associated Factor ATRX from Nuclear Domain 10 at Early Stages of Infection. Lukashchuk, V, et al.
Journal of Virology. 2008.epublication ahead of print:.
摘要
Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. Loo, YM, et al.
J Virol. 2008.82: 335-45.
摘要
HMGA1 is a molecular determinant of chemoresistance to gemcitabine in pancreatic adenocarcinoma. Liau, SS, et al.
Clin Cancer Res. 2008.14: 1470-7.
摘要
SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects. Lepagnol-Bestel, AM, et al.
Mol Psychiatry. 2008.13: 385-97.
摘要
An immortalization-dependent switch in integrin function up-regulates MMP-9 to enhance tumor cell invasion. Lamar, JM, et al.
Cancer Res. 2008.68: 7371-9.
摘要
VIP and VIP gene silencing modulation of differentiation marker N-cadherin and cell shape of corneal endothelium in human corneas ex vivo. Koh, SW, et al.
Invest Ophthalmol Vis Sci. 2008.49: 3491-8.
摘要
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway. Kim, JH, et al.
J Biol Chem. 2008.283: 708-15.
摘要
DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress. Kappes, F, et al.
Mol Cell Biol. 2008.28: 3245-57.
摘要
Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells. Jong, A, et al.
Cellular Microbiology. 2008.epublication ahead of print:.
摘要
Up-regulation of Mcl-1 Is Critical for Survival of Human Melanoma Cells upon Endoplasmic Reticulum Stress. Jiang, C, et al.
Cancer Research. 2008.68:6708.
摘要
Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. Jiang, CC, et al.
Cancer Res. 2008.68: 6708-17.
摘要
Protein kinase A (PKA) isoform RIIbeta mediates the synergistic killing effect of cAMP and glucocorticoid in acute lymphoblastic leukemia cells. Ji, Z, et al.
J Biol Chem. 2008.283: 21920-5.
摘要
Epigenetic silencing of O6-methylguanine-DNA methyltransferase gene in NiS-transformed cells. Ji, W, et al.
Carcinogenesis. 2008.epublication ahead of print:.
摘要
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Janoueix-Lerosey, I, et al.
Nature. 2008.455: 967-70.
摘要
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Ishikawa, H, et al.
Nature. 2008.455: 674-8.
摘要
Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway. Hoskins, E, et al.
Oncogene. 2008.epublication ahead of print:.
摘要
Targeting AKT Signaling Sensitizes Cancer to Cellular Immunotherapy. Hahnel, P, et al.
Cancer Research. 2008.68:3899.
摘要
A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion. Gu, J, et al.
FEBS Journal. 2008.275: 3145-56.
摘要
Deferiprone targets aconitase: implication for Friedreich's ataxia treatment. Goncalves, S, et al.
BMC Neurol. 2008.8:20.
摘要
Ethanol enhances tau accumulation in neuroblastoma cells that inducibly express tau. Gendron, TF, et al.
Neurosci Lett. 2008.443: 67-71.
摘要
Induction of autophagy during extracellular matrix detachment promotes cell survival. Fung, C, et al.
Mol Biol Cell. 2008.19: 797-806.
摘要
Malignant pleural mesothelioma-targeted CREBBP/EP300 inhibitory protein 1 promoter system for gene therapy and virotherapy. Fukazawa, T, et al.
Cancer Res. 2008.68: 7120-9.
摘要
Matrix metalloproteinase-10 is a critical effector of protein kinase C iota-Par6 alpha-mediated lung cancer. Frederick, L, et al.
Oncogene. 2008.epublication ahead of print:.
摘要
Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting in human somatic cells. Fattah, FJ, et al.
Proc Natl Acad Sci U S A. 2008.105: 8703-8.
摘要
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis. Escriva, M, et al.
Mol Cell Biol. 2008.28: 1528-40.
摘要
Interferon regulatory factors are transcriptional regulators of adipogenesis. Eguchi, J, et al.
Cell Metab. 2008.7: 86-94.
摘要
Lentiviral short hairpin RNA screen of genes associated with multidrug resistance identifies PRP-4 as a new regulator of chemoresistance in human ovarian cancer. Duan, Z, et al.
Mol Cancer Ther. 2008.7: 2377-85.
摘要
Functional characterization of the atopy-associated gene PHF11. Clarke, E, et al.
J Allergy Clin Immunol. 2008.121: 1148-54 e3.
摘要
Twist Is Transcriptionally Induced by Activation of STAT3 and Mediates STAT3 Oncogenic Function. Cheng, G, et al.
Journal of Biological Chemistry. 2008.283:14665.
摘要
Widespread microRNA repression by Myc contributes to tumorigenesis. Chang, TC, et al.
Nat Genet. 2008.40: 43-50.
摘要
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle Stem Cells. Carlson, ME, et al.
Nature. 2008.454: 528-32.
摘要
The requirement for SNF5/INI1 in adipocyte differentiation highlights new features of malignant rhabdoid tumors. Caramel, J, et al.
Oncogene. 2008.27: 2035-44.
摘要
RhoA-dependent regulation of cell migration by the tumor suppressor hSNF5/INI1. Caramel, J, et al.
Cancer Res. 2008.68: 6154-61.
摘要
E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence. Callejas-Valera, JL, et al.
J Biol Chem. 2008.283: 13450-8.
摘要
p63 regulates the caspase-8-FLIP apoptotic pathway in epidermis. Borrelli, S, et al.
Cell Death & Differentiation. 2008.epublication ahead of print:.
摘要
Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer. Bernard-Pierrot, I, et al.
Cancer Res. 2008.68: 7165-75.
摘要
Targeting Cancer Stem Cells through L1CAM Suppresses Glioma Growth. Bao, S, et al.
Cancer Research. 2008.68:6043.
摘要
HTLV-1 tax-induced NF-kappaB activation is synergistically enhanced by 12-O-tetradecanoylphorbol-13-acetate: mechanism and implications for Tax oncogenicity. Azran-Shaish, I, et al.
J Mol Med. 2008.86: 799-814.
摘要
Control of AMPK-related kinases by USP9X and atypical Lys29/Lys33-linked polyubiquitin chains. Al-Hakim, AK, et al.
Biochem J. 2008.
摘要
Effect of Disrupting Seven-in-Absentia Homolog 2 Function on Lung Cancer Cell Growth. Ahmed, A, et al.
JNCI Journal of the National Cancer Institute. 2008.epublication ahead of print:.
摘要
Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212. Yang, L, et al.
J Biol Chem. 2007.282: 10981-7.
摘要
Targeting of FAK Ser910 by ERK5 and PP1delta in non-stimulated and phorbol ester-stimulated cells. Villa-Moruzzi, E, Biochem J. 2007.408: 7-18. 摘要
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40. Vander Haar, E, et al.
Nat Cell Biol. 2007.9: 316-23.
摘要
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis. Scholl, C, et al.
J Clin Invest. 2007.117: 1037-48.
摘要
Inhibition of RAS-mediated transformation and tumorigenesis by targeting the downstream E3 ubiquitin ligase seven in absentia homologue. Schmidt, RL, et al.
Cancer Res. 2007.67: 11798-810.
摘要
Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease. Sanchez-Sanchez, F, et al.
J Biol Chem. 2007.282: 27810-24.
摘要
The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Rizzi, M, et al.
J Leukoc Biol. 2007.81: 1599-608.
摘要
c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation. Ravitz, MJ, et al.
Cancer Res. 2007.67: 11209-17.
摘要
Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis. Qian, YW, et al.
J Lipid Res. 2007.48: 1488-98.
摘要
Expression of SMARCB1 modulates steroid sensitivity in human lymphoblastoid cells: identification of a promoter SNP that alters PARP1 binding and SMARCB1 expression. Pottier, N, et al.
Hum Mol Genet. 2007.16: 2261-71.
摘要
BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis. Patel, JH, et al.
J Biol Chem. 2007.282: 5-13.
摘要
Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse Development. Pallerla, SR, et al.
Dev Dyn. 2007.236: 556-63.
摘要
Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways. Neilson, LM, et al.
Mol Endocrinol. 2007.21: 2218-32.
摘要
HOXB13 promotes ovarian cancer progression. Miao, J, et al.
Proc Natl Acad Sci U S A. 2007.104: 17093-8.
摘要
Overexpression of HMGA1 promotes anoikis resistance and constitutive Akt activation in pancreatic adenocarcinoma cells. Liau, SS, et al.
Br J Cancer. 2007.96: 993-1000.
摘要
TTF-1 regulates growth hormone and prolactin transcription in the anterior pituitary gland. Lee, NO, et al.
Biochem Biophys Res Commun. 2007.362: 193-9.
摘要
Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein. Lee, H, et al.
Mol Cell Biol. 2007.27: 2103-19.
摘要
Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA. Kim, JS, et al.
Mol Cell Biol. 2007.27: 662-77.
摘要
GATA-6 mediates human bladder smooth muscle differentiation: involvement of a novel enhancer element in regulating alpha-smooth muscle actin gene expression. Kanematsu, A, et al.
Am J Physiol Cell Physiol. 2007.293: C1093-102.
摘要
A screen of shRNAs targeting tumor suppressor genes to identify factors involved in A549 paclitaxel sensitivity. Ji, D, et al.
Oncol Rep. 2007.18: 1499-505.
摘要
Non-classical export of epimorphin and its adhesion to alphav-integrin in regulation of epithelial morphogenesis. Hirai, Y, et al.
J Cell Sci. 2007.120: 2032-43.
摘要
cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis. Guicciardi, ME, et al.
Am J Physiol Gastrointest Liver Physiol. 2007.292: G1337-46.
摘要
Therapeutic application of RNAi: is mRNA targeting finally ready for prime time? Grimm, D, et al.
J Clin Invest. 2007.117: 3633-41.
摘要
Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. Gatot, JS, et al.
J Biol Chem. 2007.282: 31131-46.
摘要
Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles. Frohling, S, et al.
Cancer Cell. 2007.12: 501-13.
摘要
Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor. Fang, HL, et al.
J Pharmacol Exp Ther. 2007.323: 586-98.
摘要
Heat shock factor 1 is a powerful multifaceted modifier of Carcinogenesis. Dai, C, et al.
Cell. 2007.130: 1005-18.
摘要
EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells. Cortina, C, et al.
Nat Genet. 2007.39: 1376-83.
摘要
Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer. Chiappetta, G, et al.
Endocr Relat Cancer. 2007.14: 405-20.
摘要
Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage. Cheng, A, et al.
J Neurosci. 2007.27: 3722-33.
摘要
Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification. Carrithers, MD, et al.
J Immunol. 2007.178: 7822-32.
摘要
Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor gamma and calcium signaling in human colorectal cancer cells. Bush, CR, et al.
J Biol Chem. 2007.282: 23387-401.
摘要
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Binne, UK, et al.
Nat Cell Biol. 2007.9: 225-32.
摘要
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Bar, EE, et al.
Stem Cells. 2007.25: 2524-33.
摘要
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Yousefi, S, et al.
Nat Cell Biol. 2006.8: 1124-32.
摘要
Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. Takeda, S, et al.
Genes Dev. 2006.20: 2397-409.
摘要
Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Sykes, SM, et al.
Mol Cell. 2006.24: 841-51.
摘要
Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling. Smoak, K, et al.
Mol Cell Biol. 2006.26: 9126-35.
摘要
Genome-scale loss-of-function screening with a lentiviral RNAi library. Root, DE, et al.
Nat Methods. 2006.3: 715-9.
摘要
Lentivirus-mediated RNA interference of HMGA1 promotes chemosensitivity to gemcitabine in pancreatic adenocarcinoma. Liau, SS, et al.
J Gastrointest Surg. 2006.10: 1254-62; discussion 63.
摘要
HMGA1 is a determinant of cellular invasiveness and in vivo metastatic potential in pancreatic adenocarcinoma. Liau, SS, et al.
Cancer Res. 2006.66: 11613-22.
摘要
Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Fu, Z, et al.
Mol Cell Biol. 2006.26: 8639-54.
摘要
PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0. Everett, RD, et al.
J Virol. 2006.80: 7995-8005.
摘要
Axl receptor activation mediates laminar shear stress anti-apoptotic effects in human endothelial cells. D'Arcangelo, D, et al.
Cardiovasc Res. 2006.71: 754-63.
摘要
Genome-wide application of RNAi to the discovery of potential drug targets. Ito, M, et al.
FEBS Lett. 2005.579: 5988-95.
摘要
Stable suppression of gene expression in murine embryonic stem cells by RNAi directed from DNA vector-based short hairpin RNA. Tang, FC, et al.
Stem Cells. 2004.22: 93-9.
摘要
Lentivirus-delivered stable gene silencing by RNAi in primary cells. Stewart, SA, et al.
RNA. 2003.9: 493-501.
摘要
Induction of an interferon response by RNAi vectors in mammalian cells. Bridge, AJ, et al.
Nat Genet. 2003.34: 263-4.
摘要
Promoter choice affects the potency of HIV-1 specific RNA interference. Boden, D, et al.
Nucleic Acids Res. 2003.31: 5033-8.
摘要
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Broad 论文
标题 作者/期刊 摘要
Forward RNAi screens in primary human hematopoietic stem/progenitor cells. Ali, N et al.
Blood 2009.  epublication ahead of print
摘要
Identification of RPS14 as a 5q-syndrome gene by RNA interference screen Ebert, BL et al. 
Nature 2008. 451: 335-9
摘要
Interferon regulatory factors are transciptional regulators of adipogenesis Eguchi, J et al. 
Cell Metab 2008. 7: 86-94
摘要
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity Firestein, R et al. 
Nature 2008. 455: 547-51
摘要
Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles Frohling, SC et al. 
Cancer Cell 2007. 12: 501-13
摘要
Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3 Jones, DC et al. 
Science 2006. 312:1223-7
摘要
Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL Oberdoerffer, S et al. 
Science 2008. 321: 686-91
摘要
A mitochondrial protein compendium elucidates complex I disease biology Pagliarini, DJ et al. 
Cell 2008. 134: 112-23
摘要
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis Scholl CD et al. 
JCI 2007. 117:1037-48
摘要
Inhibition of casein kinase 1-epsilon induces cancer-cellselective, PERIOD2-dependent growth arrest Yang WS, et al. 
Genome Biol 2008. 9: R92.
摘要
Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Boehm, J. S. et al.
Cell 2007. 129: 1065-1079.
摘要
Wild-type NRas and KRas perform distinct functions during transformation. Fotiadou, P. P., Takahashi, C., Rajabi, H. N., Ewen, M. E.
Mol. Cell. Biol. 2007. 27: 6742-6755.
摘要
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Kim, M. et al.
Cell 2006. 125: 1269-1281.
摘要
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Moffat, J. et al.
Cell 2006. 124: 1283-1298.
摘要
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Sancak, Y. et al.
Mol. Cell 2007. 25: 903-915.
摘要
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