Technology Spotlights

NEW! PEPPSI™ Catalysts

NEW! Jamison Nickel (II) Precatalysts

NEW! SLAP Reagents for Piperazine Synthesis

NEW! KitAlysis™ High-Throughput Screening Platform

NEW! Reducing Organic Photoredox Catalysts for Visible Light-Driven Polymer and Small Molecule Synthesis

By Application Area

Peptide Synthesis

• Peptide Coupling Reagents Selection Guide (2017)

Cross-Coupling

• PEPPSI™ Catalysts (2018)
• SLAP Reagents for Piperazine Synthesis (2018)
• Reducing Organic Photoredox Catalysts for Visible Light-Driven Polymer and Small Molecule Synthesis (2018)
• SnAP Reagents (2015)
• Buchwald GT Capsules for Cross-Coupling (2015)
• G3 and G4 Buchwald Precatalyst (2015)
  
• Broad Application Doyle Nickel Precatalyst (2015)
• Fro-DO: Novel Ligand for Quaternary Carbon-Carbon Coupling (2015)
• Buchwald Portfolio - Precatalysts and Ligands (2015)
• Photoredox Iridium Catalyst for Single Electron Transfer (SET) Cross-Coupling (2015)
  
• PEPPSI™-IPent for Demanding Cross-Coupling Reactions (2015)
• Application Guide for Palladium Catalyzed Cross -Coupling Reactions (2011)
• DalPhos Ligands (2011)
• 2^nd Generation Buchwald Precatalysts (2011)
• Potassium Organotrifluoroborates (2011)
• New MIDA Boronates  (2011)

Chemical Biology

• Trifunctional Probe Building Blocks (2017)
• Heterocycle and Cyclic Peptide Formation with N-(isocyamino)triphenylphosphorane (Pinc) (2017)
• Probes for ¹⁹F Magnetic Resonance Imaging: PERFECTA (2017)
• Screening Library of Serine Hydrolase Inhibitors (2016)
• Arginine-Directed Bioconjugation (2016)
• Quorum Sensing Molecules (2016)
• Baseclick EdU Cell Proliferation Detection Kits: Improve Data Quality and Save Time (2015)

Innovative Molecules for Complex Synthesis

• Ynamides: Versatile and Enabling Building Blocks (2015)
• Inverse Electron Demand Diels–Alder Reactions (2015)
• Spirocyclic Building Blocks (2015)
• Yudin and Coworkers Develop a New Line of MIDA Boronate Esters: Amphoteric Alpha-Boryl Aldehydes (2012)

Asymmetric Synthesis

• Kwon Chiral Phosphines (2016)
• Homobenzotetramisole (HBTM): A General Organocatalyst for Asymmetric Acylations (2014)
• Highly Selective Ubaphox Iridium Catalysts for Asymmetric Hydrogenations (2012)
• JoSPOphos: A New Class of Ligands for Asymmetric Hydrogenation (2012)
• EZ-CrotylMix Reagents  (2011)

Synthetic Reagents

• Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions (2017)
• Preparing Terminal Alkynes: Vinyl N,N-Diisopropylcarbamate for Stereospecific Alkynylation of Chiral Boronic Esters (2017)
• Electrochemical Allylic C–H Oxidation with N-Hydroxytetrachlorophthalimide (TCNHPI) (2016)
• Deoxyfluorination with PyFluor (2015)
• DMPU-HF: Novel Nucleophilic Fluorination (2015)
• Stahl Aerobic Oxidation Solutions (2015)
• PhenoFluor™: A Deoxyfluorinating Reagent Convenient Enough to Use in the Hood (2015)
• Sulfonyl Fluorides (SuFEx): A New Click Reaction (2015)
• Palau’Chlor^®: Easily and Selectively Functionalize Lead Compounds (2014)
• Heterocyclic Aryne Precursors: New Opportunities for the Synthesis of Highly Substituted Indoles and Pyridines (2013)
• Application of Carbon Monoxide in Synthesis Made Simple and Safe by Prof. Skrydstrup and Coworkers (2013)
• New Diazoacetate Formulations (2011)
• Potassium Carbobenzyloxycyanamide: An Efficient Reagent for Amine Guanylation (2011)
• New Arene Trifluoromethylation Reagent: (Phen)Cu-CF₃ (2011)

Greener Methods

• Second-Generation, Designer-Surfactant Kits (2015)
• Nok – Third Generation Amphiphile for Cross-Coupling Chemistry in Water (2014)
• Greener Methods: Ester Hydrogenation (2013)
• Greener Methods: Catalytic Amide Bond Formation (2013)
• TPGS–750–M: Second Generation Amphiphile for Organometallic Chemistry in Water @ RT (2011)

C-H Functionalizations

• Modified Norbornene for Meta-C-H Alkylation and Arylation (2015)
• Quinoline Ligands: Pd-Catalyzed C-H Activation (2015)
• Diversinates™: Any-Stage Functionalization of (Hetero)aromatic Scaffolds (2014)
• Diversinates™: Linkers for Native Chemical Tagging of C–H Bonds (2014)
• Yu-Wasa Auxiliary for C(sp³)-H Activation (2014)

Catalysis

• Jamison Nickel (II) Precatalysts (2018)
  
• KitAlysis™ High-Throughput Screening Platform (2018)
• Reducing Organic Photoredox Catalysts for Visible Light-Driven Polymer and Small Molecule Synthesis (2018)
• Dehydrogenation through Cooperative Base Metal Catalysis (2017)
• AlPhos and [(AlPhosPd)₂•COD] for Pd-Catalyzed Fluorination (2016)
• Bode Kinetic Resolution (2016)
• Aldrich Micro Photochemical Reactor (2016)
• BisPhePhos XD Gold(I) Chloride for Cationic Gold Catalysis (2015)
• Hazari Pd Precatalyst Dimer (2015)
• Nicewicz Photoredox Catalysts for Anti-Markovnikov Alkene Hydrofunctionalization (2015)
• Simplified Olefin Isomerization by Cobalt/Silane (2015)
• Rovis N-Heterocyclic Carbene (RoNHC) Catalysts (2014)
• Photocatalysis (2014)
• Chiral Disulfonimides: New Products for Asymmetric Counteranion Directed Catalysis (ACDC) (2014)
• Hartwig Nickel Precatalysts (2014)
• Cationic Gold(I) Complexes Based on Bulky Phosphine Ligands: New Opportunity for Efficient Gold Catalysis (2013)

Organocatalysis

• Chiral Phosphoric Acids: Versatile Organocatalysts with Expanding Applications (2013)

Technology Spotlights Archive