Custom Capabilities

Sigma-Aldrich is a world-leading chemistry and biochemistry partner focused on meeting the special needs of customers across every phase of bringing new products to market. While we originally focused on providing high quality reagents aimed at discovery research, today’s Sigma-Aldrich brings customers a unique understanding of the highly-specialized requirements and capabilities associated with all phases of development and manufacturing.

From the timely procurement of supply chain raw materials, to regulatory guidance, to pilot and commercial scale custom manufacturing, more than 1.3 million customers annually depend upon Sigma-Aldrich to support their projects with customization beyond expectation.

We provide:

  Inside a distribution warehouse

Supply Chain
Streamline Procurement
Rely on Superior Supply Chain Expertise Including:

  • Lot-to-lot QC testing to ensure quality
  • Complete supply chain transparency and documentation
  • Purification and custom packaging as required
  • Leading global distribution expertise

  Worker in a manufacturing site

Contract Manufacturing
Accelerate Development
Sigma-Aldrich’s Unparalleled Expertise Includes:

  • Extensive range of chemical and biochemical synthesis capabilities
  • Broad inventory of key starting materials
  • 38 global manufacturing sites with over 50,000 procedures on file
  • Proven technology transfer
  • Project Management  that keeps project on track

  Man performing check

Quality Assurance
Mitigate Risk
Key Quality Assurance Program Components:

  • Comprehensive traceability and safety documentation
  • Change Control Notification (CCN) program linked with our quality assurance process
  • Corrective and Preventative Action Program (CAPA)
  • Certified manufacturing facilities ranging from ISO:9001 to cGMP

 Worker running product test

Quality Control
Understand Quality Requirements
Analytical Service Capabilities Include:

  • In-house quality control testing at 18 global locations
  • Statistical QC and process control for critical raw materials
  • Over 340 dedicated quality control specialists on-staff performing more than 500,000 tests annually
  • Comprehensive analytical technology range, including EDXRF, Maldi-TOF, Multinuclear FTNMR capability, ICPMS, LCMS and GC-MS/MS

  Rows of bottles



Unrivaled Flexibility
Packaging Formats Include:
  • Ampules
  • Bags
  • Bottles
  • Boxes
  • Cans
  • Cylinders
  • Drums
  • Returnable Containers
Key Packaging Capabilities:


  • Air sensitive materials
  • High purity materials
  • Hazardous chemicals
  • Sterile filtration
  • Suspension
  • Blending

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Contact Us
Customization Beyond Expectation
Sigma-Aldrich offers customers a unique combination of breadth and depth of manufacturing expertise. Our dedication to supply chain and quality allows us to deliver solutions to meet your raw material sourcing and development needs.

Contact us for more information on how our custom capabilities can exceed your expectations.

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